(n.) The fluid essence or pure spirit obtained by distillation.
(n.) Pure spirit of wine; pure or highly rectified spirit (called also ethyl alcohol); the spirituous or intoxicating element of fermented or distilled liquors, or more loosely a liquid containing it in considerable quantity. It is extracted by simple distillation from various vegetable juices and infusions of a saccharine nature, which have undergone vinous fermentation.
(n.) A class of compounds analogous to vinic alcohol in constitution. Chemically speaking, they are hydroxides of certain organic radicals; as, the radical ethyl forms common or ethyl alcohol (C2H5.OH); methyl forms methyl alcohol (CH3.OH) or wood spirit; amyl forms amyl alcohol (C5H11.OH) or fusel oil, etc.
Example Sentences:
(1) These variants may serve as useful gene markers in alcohol research involving animal model studies with inbred strains in mice.
(2) PMS is more prevalent among women working outside the home, alcoholics, women of high parity, and women with toxemic tendency; it probably runs in families.
(3) The 14C-aminopyrine breath test was used to measure liver function in 14 normal subjects, 16 patients with alcoholic cirrhosis, 14 alcoholics without cirrhosis, and 29 patients taking a variety of drugs.
(4) The pancreatic changes are unlikely to be an artefact, but rather a direct toxic effect of the alcohol as confirmed by the biochemical changes.
(5) Evidence of fetal alcohol effects may be found for each outcome category.
(6) The difference in HDL and HDL2 cholesterol concentrations between the MI+ and MI- groups or between the MI+ and CHD- groups persisted after adjustment by analysis of covariance for the effect of physical activity, alcohol intake, obesity, duration of diabetes, and glycemic control.
(7) Veterans admitted to a 90-day alcoholism treatment program were administered the MMPI, and those who completed the program were retested before discharge.
(8) 1 The effects of chronic ethanol intake on the elimination kinetics of antipyrine were determined in nineteen male alcoholic subjects with comparison made to fourteen male volunteers.
(9) This study examines the costs of screening patients for alcohol problems.
(10) Alcohol abuse remains the predominant cause of chronic liver disease in the Western world.
(11) The acute effect of alcohol manifested itself by decreasing mitochondrial respiration, compensated by increased glycolytic activity of the myocardium so that myocardial energy phosphate concentration remained unchanged.
(12) The transmission of alcoholism and its effects are thereby lessened for future generations of children of alcoholics.
(13) More chronic use of alcohol resulted in a suppression of LH.
(14) Because of increasing alcoholism the importance of alcoholic organ lesions is also increasing.
(15) Allergic photocontact dermatitis developed in a patient to a commercial sunscreen preparation containing para-aminobenzoic acid (PABA) in an alcohol base.
(16) The patients had a high AP, consumed more alcohol, were more well-fed, older and consumed more refined carbohydrates per 1 kg bw and less cholesterol and vegetable protein.
(17) We found that whereas idarubicin was 2-5 times more potent than the other three anthracycline analogs against these tumor cell lines, idarubicinol was 16-122 times more active than the other alcohol metabolites against the same three cell lines.
(18) The phenomenon can be ascribed to the decrease in charge density due to the incorporation of dodecyl alcohol into SDS micelles.
(19) Most of the progressive cases were alcoholic, and some showed progression to advanced pancreatitis within 4 years.
(20) These data indicate that the development of HCC in HBV-negative alcoholics with cirrhosis occurs in relation to the development of macronodules and loss of liver weight, most likely along with the prolongation of the life span.
Tetrol
Definition:
(n.) A hypothetical hydrocarbon, C4H4, analogous to benzene; -- so called from the four carbon atoms in the molecule.
Example Sentences:
(1) The amount of administered tetrol recovered unchanged ranged from 1 to 88%.
(2) Studies were designed to elucidate the origin of estetrol (15alpha-hydroxyestriol (estra-1,3,5(10)triene-3,15alpha,17beta-tetrol) or E4) during late human pregnancy.
(3) To improve the identification of the DNA adducts formed, an acid hydrolysis technique was used to convert the BPD- and anti-BPDE-deoxyribonucleoside adducts formed in mouse and rat skin to BP tetrols.
(4) Four substances from the urine of a hypertensive newborn girl were partially characterized and shown to be 17alpha-hydroxy-5beta-pregnane-1,3,20-trione, 3alpha,17alpha-dihydroxy-5beta-pregnane-1,20-dione, 3alpha,17alpha,20alpha-trihydroxy-5beta-pregnan-1-one and 5beta-pregnane-1beta,3alpha,17alpha,20alpha-tetrol.
(5) The 5beta-[24-14C]cholestane-3alpha, 7alpha, 25-triol was hydroxylated in the liver at the 12alpha position to yield the corresponding 5beta-cholestane-3alpha, 7alpha, 12alpha, 25-tetrol.
(6) The major ethylacetate extractable metabolites of BP formed by peripheral lung were tetrols and trans-7,8-diol.
(7) and mass-spectral examination of which suggested the structure 5alpha-cholane-3alpha,7alpha,12alpha,24-tetrol.
(8) The following materials were obtained by this method: 5 alpha-anhydrocyprinol, 5 alpha-cholestane-3 alpha,7 alpha,12 alpha,25-tetrol, 5 alpha-cholestane 3 alpha,7 alpha,12 alpha,26-tetrol, an unidentified sterol from the neutral lipid fraction, allocholic acid and allochenodeoxycholic acid from the bile acid fraction.
(9) The major metabolite in all incubations was very similar, but not identical, in chemical and chromatographic properties to 5 beta-pregnane-3 alpha, 6 alpha, 17,20 beta-tetrol.
(10) Thus, this study indicates that 5 beta-cholestane-3 alpha, 7 alpha, 12 alpha, 25-tetrol is an inefficient substrate for cholic acid biosynthesis in man and that the major route of cholic acid synthesis probably involves the 26-hydroxylated intermediate.
(11) Small amounts of the sulphate conjugate, 9-hydroxy-benzo[a]pyrene and the tetrols were also detected.
(12) We have evaluated both electron ionization (EI) and negative-ion chemical ionization (NICI) methods for the analysis of trimethylsilyl derivatives of a series of polycyclic aromatic hydrocarbon (PAH) alcohols including styrene diol, benzo[e]pyrene diol and tetrols, cyclopenta[c,d]pyrene diols, benzo[a]pyrene-4,5-diols, chrysene tetrols, benz[a]anthracene tetrols I and II, and syn- and anti-benzo[a]pyrene tetrols.
(13) The structure of tetrol 4 was confirmed by X-ray diffraction.
(14) The main toxin of both species was identified by mass spectrometric and nuclear magnetic resonance analyses as the 2,2'-bipyridine-3,3',4,4'-tetrol-1,1'-dioxide, which is identical to orellanine.
(15) A major metabolite, present in all three fractions, was tentatively identified as 5 alpha-pregnane-3 beta,7 alpha,17,20 beta-tetrol.
(16) The percentage of 20 beta-epimers of 3 alpha, 17 alpha, 20-trihydroxy-5 beta-pregnan-11-one, 5 beta-pregnane-3 alpha, 11 beta, 17 alpha, 20-tetrol (in the normotensive CAH, PVS and POS) and 5 alpha- or 5 beta-pregnane-3 alpha, 17 alpha, 20, 21-tetrol (in the hypertensive CAH) varied from nil to 76%.
(17) The assay for BaP-globin adducts was based on the release of tetrahydroxy-BaP (BaP-tetrols) from globin by mild acid hydrolysis.
(18) BaP-tetrol levels were measured in rats dosed intraperitoneally with 242, 71 and 24 mumol BaP kg-1 body weight in corn oil.
(19) The structure of clinopodiside A was elucidated by spectroscopic and X-ray diffraction analysis as 3-O-beta-D-glucopyranosyl (1----6)-[beta-D-glucopyranosyl (1----4)]-beta-D-glucopyranosyl-olean-11, 13 (18)-diene-3 beta, 16 beta, 23, 28-tetrol.
(20) BP-tetrols were detected in extracts from 8 placentas: 5 of 7 from smokers and 3 of 9 from nonsmokers.