(v. t.) To render larger, more extended, or more intense, and the like; -- used especially of telescopes, microscopes, etc.
(v. t.) To enlarge by addition or discussion; to treat copiously by adding particulars, illustrations, etc.; to expand; to make much of.
(v. i.) To become larger.
(v. i.) To speak largely or copiously; to be diffuse in argument or description; to dilate; to expatiate; -- often with on or upon.
Example Sentences:
(1) We used the polymerase chain reaction (PCR) to amplify the breakpoint area of alpha-thalassemia-1 of Southeast Asia type and several parts of the alpha-globin gene cluster to make a differential diagnosis between alpha-thalassemia-1 and Hb Bart's hydrops fetalis.
(2) We have investigated the increase in the spcDNA population upon cycloheximide treatment of individual sequences, which are found to amplify differentially.
(3) We conclude that only one of the alleles was amplified and that either allele could be amplified with respect to both the SphI and PvuII polymorphisms.
(4) RNA preparations were reverse-transcribed, amplified by a polymerase chain reaction (PCR), and separated by electrophoresis.
(5) It was previously demonstrated that multidrug-resistant Chinese hamster cell lines contain an amplified, transcriptionally active DNA sequence designated mdr.
(6) Chloroquine increased the binding of 125I-labeled insulin to rat hepatoma cells (R-Y121B) at 4 degrees C. The effect of chloroquine on insulin binding was amplified at 23 degrees C, and a large increase in cell-associated radioactivity was observed.
(7) Overexpression of asparagine synthetase in beta-aspartyl hydroxamate-resistant lines without amplified copies of the gene was also correlated with DNA hypomethylation.
(8) (iii) The insertion plasmid pRSD102(R388::Tn1721) has conserved the capacity of the original plasmid pRSD1 to amplify the 3.55 Mdal-tet region.
(9) To identify the molecular defect in a patient with the intermediate form of the disease, arylsulfatase B mRNA from his fibroblasts was reverse-transcribed, amplified by the polymerase chain reaction, and subcloned.
(10) In addition to the fatigue tester and the pulse duplicator, a signal conditioner, a DC amplifier, an analog-to-digital converter, and a digital microcomputer comprised the essential hardware.
(11) The sensitivity of a PCR system to amplify the long terminal repeat (LTR) sequence of HIV-1 was not affected by the irradiation procedure; however, the ultimate sensitivity of a PCR system for the amplification of an early gene promotor sequence of the CMV genome was reduced 1000-fold.
(12) Thus MTX combined with PALA selected cells with an 'amplificator' phenotype (an increased ability to amplify parts of the genome).
(13) HDV cDNA was then directly amplified with Taq polymerase using three pairs of specific primers.
(14) As an extension to the variety of existing techniques using polymorphic DNA markers, the Random Amplified Polymorphic DNA (RAPD) technique may be used in molecular ecology to determine taxonomic identity, assess kinship relationships, analyse mixed genome samples, and create specific probes.
(15) cDNA was prepared by reverse transcription of peripheral blood mRNA and amplified by the polymerase chain reaction (PCR) using primers corresponding to sequences 400 bp apart on the cDNA, spanning the last three exons (X, Y, Z) of the beta-Sp gene.
(16) Whether we would use that to support and amplify the community ideals already present or go the way of gentrification remained to be seen.
(17) Optimum specific amplification resulted when the primer annealing temperature was 60 degrees C. The gene fragment was amplifiable in 25 different Brucella species and strains.
(18) The action of exogenous etiologic agents is usually mediated in part or amplified by endogenous mediators that very often exert biphasic, i.e., damaging and protective, effects.
(19) By using primer 1 (5'-AAAGAATTCATGGAATCCAGGATCTG-3', upstream nucleotides 157 to 2877), primer 2 (5'-AAAGAATTCATGAACGTGAAGGAATCG-3', upstream nucleotides 1846 to 2877), and primer 4(5'-ATAAAGCTTAATCAGACGTTCTCTTCTTC-3', downstream nucleotides 157 to 2877 and 1846 to 2877), the HCMV B gene code region sequence and its glycoprotein 52 kd antigenic domain sequence were amplified from the recombinant plasmid pBH1 DNA containing the HCMV B gene.
(20) The PCR amplified a 375-bp DNA fragment which was cloned and sequenced; the deduced amino acid sequence had significant identity with known TS sequences, including strict conservation of all phylogenetically invariant TS amino acid residues.
Muffle
Definition:
(n.) The bare end of the nose between the nostrils; -- used esp. of ruminants.
(v. t.) To wrap up in something that conceals or protects; to wrap, as the face and neck, in thick and disguising folds; hence, to conceal or cover the face of; to envelop; to inclose; -- often with up.
(v. t.) To prevent seeing, or hearing, or speaking, by wraps bound about the head; to blindfold; to deafen.
(v. t.) To wrap with something that dulls or deadens the sound of; as, to muffle the strings of a drum, or that part of an oar which rests in the rowlock.
(v. i.) To speak indistinctly, or without clear articulation.
(v. t.) Anything with which another thing, as an oar or drum, is muffled; also, a boxing glove; a muff.
(v. t.) An earthenware compartment or oven, often shaped like a half cylinder, used in furnaces to protect objects heated from the direct action of the fire, as in scorification of ores, cupellation of ore buttons, etc.
(v. t.) A small oven for baking and fixing the colors of painted or printed pottery, without exposing the pottery to the flames of the furnace or kiln.
(v. t.) A pulley block containing several sheaves.
Example Sentences:
(1) Weirdly, the muffled Doppler effects of several thousand passing SUVs was quite soothing.
(2) True diastolic pressure is usually closer to the disappearance point of Korotkoff sounds than to the muffling phase.
(3) Hence his fondness for placing the camera far away from its subjects: Hidden coolly watches as a child's small world falls apart, his cries muffled by the intervening space; and Code Unknown concludes by showing how life, likened by Haneke to a flea circus, indifferently unravels on a Paris boulevard.
(4) The presence of a muffled voice led to radiologic and indirect laryngoscopic examination confirming the diagnosis.
(5) The effect of El Niño during these years compounded the muffling effect of greenhouse gases and lead to exceptionally hot global temperatures.
(6) I heard about three or four shots fired, but they were muffled, as if taking place indoors,” one witness told Agence France-Presse.
(7) Common symptoms include fever, swollen neck, difficult swallowing, muffled voice and hyperextension of the head and neck.
(8) In places there were moans and muffled cries beneath the ruins, spurring frantic efforts to dig people out with bare hands and improvised tools.
(9) The determinations of calcium, magnesium, and phosphorus in dentine showed no significant differences between LTA, muffle furnace ashing (MFA), and wet ashing.
(10) The policemen closed the doors, but the muffled screams continued outside.
(11) The samples of the mentioned tissues were dried and ashed in the muffle furnace.
(12) Questions will undoutedly be asked about Brown's vocal capabilities – once described by Guardian critic Alexis Petridis as "a muffled, gloomy honk, like a despondent goose wearing a balaclava" – and whether the band, now in middle-age, will be able to capture the heady excitement of their early days.
(13) For some it sounded muffled and far away, as though somewhere in the distance a big balloon had popped.
(14) Once again, Vince Cable is a rather lonely prophet worrying where this will lead, but this time a voice of warning somewhat muffled by collective responsibility.
(15) Fabricant, who was strongly involved in the Tory campaign in Eastleigh, tweeted: "The Conservative voice is muffled and not crisp.
(16) But instead of a traditional riot or at least some minor destruction, the place was filled with well-behaved individuals, talking in the "inside voices" with muffled jubilation (even when the US won!).
(17) Abnormal or muffled heart sounds associated with pericarditis and epicarditis was the most common sequela, occurring in 40 cases.
(18) The polite approach of London Citizens has so far yielded muffled responses, but the issue will be raised at a November board meeting: if there is no decisive yes, expect the gloves to come off, and more direct action, including a shoppers' boycott.
(19) Inadequate velopharyngeal function, whether congenital or subsequent to palatal repair, may be masked by the presence of other speech problems in this syndrome, particularly by the "muffled" voice quality which appears to be associated with an elevated and retracted tongue posture.
(20) Extreme sore throat, pooling of oral secretions, muffled voice, and elevated temperature were uncommon.