What's the difference between anaplerotic and remedy?

Anaplerotic


Definition:

  • (a.) Filling up; promoting granulation of wounds or ulcers.
  • (n.) A remedy which promotes such granulation.

Example Sentences:

  • (1) 212, 58-62) for measuring the relative flux of molecules through the oxidative versus anaplerotic pathways involving the citric acid cycle of the rat heart has been extended to include a complete analysis of the entire glutamate 13C spectrum.
  • (2) In Saccharomyces cerevisiae, pyruvate carboxylase [EC 6.4.1.1] has an important anaplerotic role in the production of oxaloacetate from pyruvate.
  • (3) The net alanine formation in ischemia was approximately a stoichiometric glutamate decrease; the increase in the tissue malate content corresponded to the aspartate----oxaloacetate----malate anaplerotic flux, the succinate production being commensurable to alpha-ketoglutaric acid formation in the alanine aminotransferase reaction.
  • (4) These findings suggest an anaplerotic role for the enzyme and an allosteric modulation of its activity by acetyl CoA and tricarboxylic acid cycle intermediates.
  • (5) The results indicate that glutamate metabolism offers considerable anaplerotic potentials following impaired energy state after 6-AN treatment.
  • (6) During growth of Escherichia coli on acetate, isocitrate dehydrogenase (ICDH) is partially inactivated by phosphorylation and is thus rendered rate-limiting in the Krebs cycle so that the intracellular concentration of isocitrate rises which, in turn, permits an increased flux of carbon through the anaplerotic sequence of the glyoxylate bypass.
  • (7) Because acetylglutamate is regenerated as ornithine is formed, the enzyme has only a catalytic or anaplerotic role in the pathway, maintaining "bound" acetyl groups during growth.
  • (8) When cells were grown on glucose the anaplerotic function was probably fulfilled by pyruvate carboxylase, although phosphoenolpyruvate carboxylase was also present.
  • (9) The reaction may be considered as an anaplerotic sequence.
  • (10) Although still simple in practice, this more sophisticated model allows an evaluation of 13C fractional enrichment of molecules entering both the oxidative and anaplerotic pathways under steady-state conditions.
  • (11) Two different assays show that the mutant phenotype is due to a deficiency of pyruvate carboxylase (EC 6.4.1.1), an important anaplerotic enzyme.
  • (12) The model indicated that the glycolytic flux is partitioned one-third to pyruvate and two-thirds to oxalacetate and is therefore mainly anaplerotic.
  • (13) And finally, during exercise and recovery, amino acids likely play important anaplerotic functions sustaining the whole metabolic apparatus.
  • (14) The properties of this mutant confirm the anaplerotic role of this enzyme in the utilization for growth of compounds like glucose and lactate which are catabolized via pyruvate.
  • (15) In each case, the amount of [2-13C]acetate being oxidized and the relative carbon flux through anaplerotic versus oxidative pathways are evaluated.
  • (16) Mathematical models of the TCA cycle derived previously for 14C tracer studies have been extended to 13C NMR to measure the 13C fractional enrichment of [2-13C]acetyl-CoA entering the cycle and the relative activities of the oxidative versus anaplerotic pathways.
  • (17) The genes that code for isobutyrate and essential anaplerotic and amphibolic metabolism are chromosomal.
  • (18) The increase in malate in ischemic myocardium corresponded to the anaplerotic flux aspartate----oxaloacetate----malate; the succinate production being commensurable to alpha-ketoglutarate formation in the alanine aminotransferase reaction.
  • (19) The replenishment of TCA intermediates could, in theory, occur by several anaplerotic reactions, mainly those catalysed by pyruvate-carboxylase and malic enzyme.
  • (20) The foregoing evidence indicates that malate synthase G plays an anaplerotic role during growth with glycolate or acetate as the carbon source.

Remedy


Definition:

  • (n.) That which relieves or cures a disease; any medicine or application which puts an end to disease and restores health; -- with for; as, a remedy for the gout.
  • (n.) That which corrects or counteracts an evil of any kind; a corrective; a counteractive; reparation; cure; -- followed by for or against, formerly by to.
  • (n.) The legal means to recover a right, or to obtain redress for a wrong.
  • (n.) To apply a remedy to; to relieve; to cure; to heal; to repair; to redress; to correct; to counteract.

Example Sentences:

  • (1) This questionnaire asked about the patients' own diagnosis of symptoms, previous remedies and their source.
  • (2) This case study described the success of a technique labeled Multiple Oral Rereading (MOR) in the remediation of a case of acquired alexia in an adult male.
  • (3) The Conservatives are offering the gay community no new measures to remedy the remaining vestiges of homophobia and transphobia .
  • (4) A recent UN study ranked Brazil 116th out of 143 countries in terms of the proportion of women in the national legislature and efforts to remedy this with a quota system – such as those adopted by neighbouring Argentina and Bolivia – have made little headway, despite Suplicy's heavy campaigning.
  • (5) These effects are due to residual silanols on the surface of the column material and may be remedied by adding suitable amines or quaternary ammonium ions to the eluent as anti-tailing agents.
  • (6) The austerity programmes administered by western governments in the wake of the 2008 global financial crisis were, of course, intended as a remedy, a tough but necessary course of treatment to relieve the symptoms of debts and deficits and to cure recession.
  • (7) Future research should emphasize the assessment of remedial interventions.
  • (8) While interest in herbal therapy is clearly increasing in Western countries, there are few available data about hepatotoxicity of herbal remedies.
  • (9) The rich ethnopharmacological descriptions in the ancient books of herbal remedy and those scattered in the folklore medicine contribute the possibility of this approach.
  • (10) Many of the factors that make jobs difficult can be remedied without extensive cost to the employer.
  • (11) Early diagnosis, particularly at the time of operation, and remedial treatment reduce mortality.
  • (12) Organic and ionic solutes proved to be equally effective in inducing the osmotic remedial response.
  • (13) Poor crossing undermined Liverpool in the first leg, Klopp had claimed, but the flaw was remedied quickly in the return.
  • (14) Subsequent to baseline, participants used written checklists that identified potential in-home hazards but did not prompt behaviors necessary for hazard remediation.
  • (15) Continued escalation of claims frequency, however, and average paid-claim costs mean that other remedies will have to be sought if the professional liability problem is to be solved.
  • (16) Among the 630 mothers studied, it was observed that a majority of mothers (92%) would take remedial action for diarrhoea when the stool frequency was 3 or more per 12-hour period.
  • (17) Forty mutants are osmotic remedial; 17 of these, and no others, are also temperature-sensitive.
  • (18) The experiments have implications for the nonaversive remediation of self-injury in individuals who are restrained, as well as for the development and maintenance of self-injury in natural settings.
  • (19) A remedial effect other than osmotic protection of these effectors and an adaptive regulatory mechanism for PE formation are suggested.
  • (20) Those of most importance involve interaction with guanethidine-type agents and tricyclic antidepressants, amphetamine-type anorexiants or phenolpropanolamine-type common cold remedies; combined use of potassium retaining diuretics with potassium supplements; and incautious use of diuretics with cardiac glycosides.

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