(n.) A iron instrument which is attached to a ship by a cable (rope or chain), and which, being cast overboard, lays hold of the earth by a fluke or hook and thus retains the ship in a particular station.
(n.) Any instrument or contrivance serving a purpose like that of a ship's anchor, as an arrangement of timber to hold a dam fast; a contrivance to hold the end of a bridge cable, or other similar part; a contrivance used by founders to hold the core of a mold in place.
(n.) Fig.: That which gives stability or security; that on which we place dependence for safety.
(n.) An emblem of hope.
(n.) A metal tie holding adjoining parts of a building together.
(n.) Carved work, somewhat resembling an anchor or arrowhead; -- a part of the ornaments of certain moldings. It is seen in the echinus, or egg-and-anchor (called also egg-and-dart, egg-and-tongue) ornament.
(n.) One of the anchor-shaped spicules of certain sponges; also, one of the calcareous spinules of certain Holothurians, as in species of Synapta.
(v. t.) To place at anchor; to secure by an anchor; as, to anchor a ship.
(v. t.) To fix or fasten; to fix in a stable condition; as, to anchor the cables of a suspension bridge.
(v. i.) To cast anchor; to come to anchor; as, our ship (or the captain) anchored in the stream.
(v. i.) To stop; to fix or rest.
(n.) An anchoret.
Example Sentences:
(1) The haplotype of the recombinant X chromosome of each of 241 backcross progeny has been established using the X-linked anchor loci Otc, Hprt, Dmd, Pgk-1, and Amg and the additional probes DXSmh43 and Cbx-rs1.
(2) The popularly used procedure in Great Britain is that in which a sheet of Ivalon sponge is sutured to the sacrum and wrapped around the rectum thus anchoring it in place.
(3) The company also confirmed on Thursday as it launched its sports pay-TV offering at its new broadcasting base in the Olympic Park in Stratford, east London, that former BBC presenter Jake Humphrey will anchor its Premier League coverage.
(4) Since the introduction of osseointegrated titanium implants for bone-anchored facial and dental prostheses, an increasing number of irradiated patients are being treated with this technique.
(5) The brain enzyme did not contain components characteristic of the glycolipid anchors of erythrocyte acetylcholinesterases.
(6) Our findings support the proposal that bcd transcripts are selectively recognized and trapped as they enter the anterior tip of the oocyte, and suggest that this localization process is mediated by anchored sequence-specific receptors in the oocyte cytoplasm.
(7) Sanders, the Vermont senator and self-described democratic socialist, first answered questions from Fox News anchor Bret Baier over his comments in Sunday’s debate that white people “don’t know what it’s like to be living in a ghetto”.
(8) A truncated anchor-minus form of the G2 glycoprotein was found to be secreted into the culture medium, but was retained in the Golgi complex when coexpressed with the G1 glycoprotein.
(9) Major histocompatibility complex (MHC) class 1 molecules that were either transmembrane- (H-2Db) or glycosylphosphatidylinositol (GPI)-anchored (Qa2) were labeled with antibody-coated gold particles and moved across the cell surface with a laser optical tweezers until they encountered a barrier, the barrier-free path length (BFP).
(10) This lipid has a hybrid nature of an archaeal feature in alkyl glycerol diether core portion and an eucaryal feature in the polar head group identical to the conserved core structure (GlcNp(alpha 1-6)-myo-inositol 1-phosphate) of glycosylated phosphatidylinositol which serves as a membrane protein anchor in eucaryal cells.
(11) Ultrastructurally these glands had apical microvilli with associated glycocalyx and long anchoring rootlets.
(12) This was confirmed by the crystal structures, which also showed that the Gln46 amide is hydrogen bonded to the Phe100 N and O atoms, and tightly anchored in this position.
(13) Each of the two chemically identical subunits folds into a three-layer domain anchored by a large six-stranded mixed beta sheet.
(14) A group of proteins anchored to the cell by phosphatidylinositol (PI) has recently been identified.
(15) In conclusion, the N-linked sugar chains are not required for in vitro activity but required for in vivo activity, acting as anchors for the essential terminal sialic acids.
(16) Replacement of the COOH-terminal hydrophobic domain with a signal peptide that normally functions in membrane translocation, or with a random hydrophobic sequence, results in efficient and correct processing, producing GPI-anchored DAF on the cell surface.
(17) Since the corresponding keto analogue, N-[(R)-2-benzyl-5-cyano-4-oxopentanyl]-L-phenylalanine (compound 4), does not inactivate the enzyme, it is suggested that the NH in compound 1 is critical for the proper active-site anchoring of the inhibitor for the inactivation process to take place.
(18) Facebook Twitter Pinterest Donald Trump questions US citizenship of ‘anchor babies’.
(19) This tissue may anchor the lead so that it is difficult, dangerous, or impossible to remove it.
(20) The anchoring wire can also be retracted and repositioned.
Target
Definition:
(n.) A kind of small shield or buckler, used as a defensive weapon in war.
(n.) A butt or mark to shoot at, as for practice, or to test the accuracy of a firearm, or the force of a projectile.
(n.) The pattern or arrangement of a series of hits made by a marksman on a butt or mark; as, he made a good target.
(n.) The sliding crosspiece, or vane, on a leveling staff.
(n.) A conspicuous disk attached to a switch lever to show its position, or for use as a signal.
Example Sentences:
(1) The resulting dose distribution is displayed using traditional 2-dimensional displays or as an isodose surface composited with underlying anatomy and the target volume.
(2) The hypothesis that proteins are critical targets in free radical mediated cytolysis was tested using U937 mononuclear phagocytes as targets and iron together with hydrogen peroxide to generate radicals.
(3) The fraction of the viral dose which became cell associated was independent of the incubation temperature and increased with increasing target membrane concentration.
(4) The binding properties of formalin-fixed amelanotic melanoma cells were not identical to those of endothelial or unfixed target cells.
(5) It has been generally believed that the ligand-binding of steroid hormone receptors triggers an allosteric change in receptor structure, manifested by an increased affinity of the receptor for DNA in vitro and nuclear target elements in vivo, as monitored by nuclear translocation.
(6) We sought additional evidence for an inverse relationship between functional CTL-target cell affinity on the one hand, and susceptibility of the CTL-mediated killing to inhibition by alpha LFA-1 and alpha Lyt-2,3 monoclonal antibodies on the other hand.
(7) After midazolam infusion, there was a 50% decrease in amplitude of P3 in response to target tones (P less than 0.006), whereas N3 latency increased by 40 ms (P less than 0.05).
(8) In the absence of an authentic target for the MASH proteins, we examined their DNA binding and transcriptional regulatory activity by using a binding site (the E box) from the muscle creatine kinase (MCK) gene, a target of MyoD.
(9) Despite a 10-year deadline to have the same number of ethnic minority officers in the ranks as in the populations they serve, the target was missed and police are thousands of officers short.
(10) A 24-h test trial employing a dry target demonstrated a robust memory for the training manifested in passive avoidance behavior.
(11) For related pairs, both the primes (first pictures) and targets (second pictures) varied in rated "typicality" (Rosch, 1975), being either typical or relatively atypical members of their primary superordinate category.
(12) The following conclusions emerge: (i) when the 3' or the 3' penultimate base of the oligonucleotide mismatched an allele, no amplification product could be detected; (ii) when the mismatches were 3 and 4 bases from the 3' end of the primer, differential amplification was still observed, but only at certain concentrations of magnesium chloride; (iii) the mismatched allele can be detected in the presence of a 40-fold excess of the matched allele; (iv) primers as short as 13 nucleotides were effective; and (v) the specificity of the amplification could be overwhelmed by greatly increasing the concentration of target DNA.
(13) Charge data from the target hospital showed a statistically significant reduction in laboratory charges per patient in the quarter following program initiation (P = 0.02) and no evidence for change in a group of five comparison hospitals.
(14) Consequently, it is important to predict accurately dose for such fields to ensure adequate coverage of the target region and sparing of healthy tissues.
(15) Three effector: target ratios (6.2:1, 25:1, and 50:1) were studied in quadruplicate using 3, 4 and 5-h incubations.
(16) It is proposed that microoscillations of the eye increase the threshold for detection of retinal target displacements, leading to less efficient lateral sway stabilization than expected, and that the threshold for detection of self motion in the A-P direction is lower than the threshold for object motion detection used in the calculations, leading to more efficient stabilization of A-P sway.
(17) However, since these levels were unaltered by reducing the antiandrogen dosage, the main action of the therapy is probably that of the antiandrogen within the target cells.
(18) We are pleased to see the process moving forward and look forward to its resolution,” a Target spokeswoman, Molly Snyder, said in an emailed statement.
(19) The matter is now in the hands of the Guernsey police and the law officers.” One resident who is a constant target of the paper and has complained to police, Rosie Guille, said the allegations had a “huge impact on morale” on the island.
(20) This article describes a method of selecting a potentially successful strategy using a combination of two factors: change target and level of change willingness and ability.