(n.) Opposition of action; counteraction or contrariety of things or principles.
Example Sentences:
(1) Intrathecal injection of zopiclone potentiated morphine antinociception, while the intracerebroventricular injection of zopiclone failed to enhance morphine antinociception and the intracerebroventricular injection of flumazepil to antagonize the intraperitoneal-zopiclone-induced increase in morphine antinociception.
(2) of PLA2 caused marked degranulation of mast cells in the rat mesentery which was facilitated by addition of calcium ion (10 mM) but antagonized by pretreating with three antiinflammatory agents.
(3) [Ca2+]i exhibited a sigmoidal dependence on [Na+]o. Mg2+, a competitive inhibitor of Na2+-Ca2+ antiport in these cells, antagonized the increase in [Ca2+]i produced by lowering [Na+]o.
(4) Increases in extracellular calcium antagonized the negative inotropic effect.
(5) In K+-depolarized basilar arteries, ifenprodil competitively antagonized the response to Ca2+, and this was enhanced by pre-incubation in calcium hopantenate.
(6) During the postovulatory phase, endogenous progesterone and the production of metabolites antagonized this effect.
(7) An antagonism is unlikely when ciprofloxacin is combined with one of the beta-lactams studied or with tobramycin.
(8) Co-application of CGS 9896, a benzodiazepine receptor antagonist, did not antagonize the guanidino compound-induced inhibition of GABA responses.
(9) Aortic rings from the rabbit were similarly potently antagonized by the protein kinase C inhibitors, however, K(+)-induced contractions were also equally sensitive to these agents in both rat and rabbit tissues.
(10) The biphasic response to (-)-(S)-Bay K 8644 and (+)-(S)-202-791 suggests that the properties of Ca++ channel activation and antagonism may reside within a single 1,4-dihydropyridine molecule.
(11) We have investigated the bacterial antagonism exerted in oral secretion by alpha-hemolytic streptococci against S. aureus and S. epidermidis.
(12) The marine natural product lophotoxin has produced a non-reversible antagonism of parasympathetic and sympathetic functions that are known to be mediated by C6 sub-type nicotinic receptors.
(13) Strains showing occasional antagonism at a particular proportion of concentrations of the test combination, were found to only be indifferent when the mean index of the fractional inhibition concentration of all checkerboard combinations was calculated.
(14) The omission of glucose induced a marked increase in the efflux of [3H]GABA, which was antagonized by TTX (1 microM), but not by MK 801 (1 microM) or DNQX (100 microM).
(15) The hyperthermia in rabbits caused by the serotonergic stimulants cited above is also antagonized by pretreatment with MS.
(16) The neuroleptic agents haloperidol, fluphenazine, domperidone, sulpiride and tiapride also antagonized emesis induced by cisplatin but only a proportion of the animals were completely protected and diazepam and prednisolone only reduced the intensity of the response.
(17) These results suggest that formoterol modifies allergen-induced airway responses through functional antagonism rather than the inhibition of inflammatory cell infiltration.
(18) Depolarizations induced by acetyl-Arg6-septide, a NK1-receptor selective agonist, were also antagonized by spantide with a pA2 of 6.5.
(19) 5-Hydroxytryptamine contracted the musculature from all parts of the respiratory tract-an effect which was specifically antagonized by both methysergide and atropine.4.
(20) K showed little activity against LTC4 but could antagonize more selectively H- and ACh-mediated effects.
Aversion
Definition:
(n.) A turning away.
(n.) Opposition or repugnance of mind; fixed dislike; antipathy; disinclination; reluctance.
(n.) The object of dislike or repugnance.
Example Sentences:
(1) Consequently, the present data indicate that training-induced changes in the CS-evoked activity of PFCm cells are significantly related to aversively conditioned bradycardia in rabbits.
(2) It is concluded that in the mouse model the ability of buspirone to reduce the aversive response to a brightly illuminated area may reflect an anxiolytic action, that the dorsal raphe nucleus may be an important locus of action, and that the effects of buspirone may reflect an interaction at 5-hydroxytryptamine receptors.
(3) The electrical stimulation of the tail associated to a restraint condition of the rat produces a significant increase of immunoreactive DYN in cervical, thoracic and lumbar segments of spinal cord, therefore indicating a correlative, if not causal, relationship between the spinal dynorphinergic system and aversive stimuli.
(4) Cadavers have a multitude of possible uses--from the harvesting of organs, to medical education, to automotive safety testing--and yet their actual utilization arouses profound aversion no matter how altruistic and beneficial the motivation.
(5) Fish were trained monocularly via the compressed or the normal visual field using an aversive classical conditioning model.
(6) A sequence of seven pairings of chili-flavored diet with prompt recovery from thiamine deficiency did significantly attenuate the innate aversion and may have induced a chili preference in at least one case.
(7) Testing of CGRP (ICV) in both single bottle conditioned-aversion and differential starvation paradigms was done.
(8) The differential results obtained in the present series of experiments with vagotomy and NaCl-induced short-term and long-term aversion learning suggest that the vagal system plays a decisive role in tasks requiring the rapid detection of an aversive substance in the gastrointestinal tract (short-term tasks).
(9) An experimental investigation of acupuncture's analgesic potency, separated from suggestion effects, is described, in which judgments of shock-elicited pain of the forearm were recorded along two separate scales: intensity and aversiveness.
(10) It was possible to achieve this very clear result although a strong aversion to animal experiments and a critical attitude toward biological research exist in Switzerland, as well as in other European countries.
(11) The characteristic heart rate deceleration shown immediately prior to the aversive stimulus by control subjects was absent in the schizophrenic group.
(12) The threshold for stimulation-produced analgesia or aversion, whichever was lowest, was determined before and after drug administration.
(13) However, they do indicate that cocaine is only a weak aversion-inducing agent.
(14) Insecure infant attachment at 16 months was associated with maternal perception of overcontrol, depressed mood state, and aversive conditioning to the impending cry in the laboratory task at the 5-month period.
(15) When the rats were given the two-bottle taste aversion test neither compound was found to be aversive.
(16) These results suggest that pharmacological doses of CCK-8 can act as an aversive stimulus during conditioning.
(17) In contrast, periadolescent animals demonstrated a marked resistance to amphetamine's taste aversion inducing properties when compared with either infant or young adult animals.
(18) In the first experiment operated rats were compared with control rats in the acquisition of a learned alcohol aversion.
(19) In the WikiLeaks cables, the US ambassador in Berlin characterised the chancellor as "risk-averse and seldom creative".
(20) In the 2 hr condition, weaker aversions were exhibited and again the 35% EDC group showed the least aversion.