(n.) One who contends with another, especially in combat; an adversary; an opponent.
(n.) A muscle which acts in opposition to another; as a flexor, which bends a part, is the antagonist of an extensor, which extends it.
(n.) A medicine which opposes the action of another medicine or of a poison when absorbed into the blood or tissues.
(a.) Antagonistic; opposing; counteracting; as, antagonist schools of philosophy.
Example Sentences:
(1) This death is also dependent on the presence of chloride and is prevented with the non-selective EAA antagonist, kynurenic acid, but is not prevented by QA.
(2) Microionophoretically applied excitatory amino acids induced firing of extracellularly recorded single units in a tissue slice preparation of the mouse cochlear nucleus, and the similarly applied antagonist 2-amino-5-phosphonovalerate (2APV) was demonstrated to be a selective N-methyl-D-aspartate (NMDA) receptor antagonist.
(3) Meanwhile the efficiency of muscarinic antagonists in inhibition of tremor reaction induced by arecoline administration is associated with interaction between the drugs and the M2-subtype.
(4) The anticonvulsant properties of the endogenous excitatory amino acid antagonist, kynurenic acid (KYA), were studied in prepubescent and adult rats using the amygdaloid kindling model of epilepsy.
(5) A novel bicyclic prostaglandin analogue, (1S)-[1 alpha,2 alpha(Z),3 alpha,4 alpha]-7-[3-[(hexylthio)methyl]-7- oxabicyclo [2.2.1]hept-2-yl]-5-heptenoic acid ((-)-10), and its cogeners were found to be potent antagonists at the TxA2 receptor.
(6) This difference was abolished by exposure of the slices to propranolol, a beta-adrenergic receptor antagonist.
(7) The TxA2 antagonistic effects of KW-3635 were compared with that of daltroban in PRP from various animals species.
(8) In experiments performed to determine whether PtdIns(4,5)P2 hydrolysis induced by TRH may have been caused by the elevation of [Ca2+]i, the following results were obtained: the effect of TRH to decrease the level of PtdIns(4,5)P2 was not reproduced by the calcium ionophore A23187 or by membrane depolarization with 50 mM K+; the calcium antagonist TMB-8 did not inhibit the TRH-induced decrease in PtdIns(4,5)P2; and, most importantly, inhibition by EGTA of the elevation of [Ca2+]i did not inhibit the TRH-induced decrease in PtdIns(4,5)P2.
(9) Similarly, 50 microM D-600, a Ca+2 channel antagonist, significantly (P less than 0.01) reduced basal and 5-HETE-induced PRL release.
(10) Selective removal of endothelium had no effect on BK-induced contraction or the action of the antagonists.
(11) The second experiments entailed use of the nonspecific opiate antagonist, naloxone, as well as the specific delta antagonist, ICI 154,129, against seizures induced by icv-administered morphine, morphiceptin, DADL, or DSLET.
(12) These antagonists reverse NMDA-mediated long term influence in these brain areas.
(13) This novel mechanism of receptor regulation, named transmodulation, should be distinguished from the reduction in total receptor number caused by the homologous ligand (downregulation) and from the change in affinity produced by the binding of agonists or antagonists to the same receptor site.
(14) Furthermore, the ability of a vasopressin antagonist to lower arterial pressure in NTS hypertensive rats was markedly attenuated by clonidine treatment.
(15) All of the serotonergic antagonists studied had additional effects on the response of the coronary artery to electrical stimulation or to norepinephrine.
(16) Their receptive fields comprise a temporally and spatially linear mechanism (center plus antagonistic surround) that responds to relatively low spatial frequency stimuli, and a temporally nonlinear mechanism, coextensive with the linear mechanism, that--though broad in extent--responds best to high spatial-frequency stimuli.
(17) The effects of low doses of dihydropyridine (DHP) calcium channel antagonists nimodipine, nifedipine, (-)-R-202-791, and amlodipine, the DHP calcium channel agonist BAY K 8644 were investigated on clonic convulsions to pentylenetetrazole (PTZ) in mice.
(18) Addition in the cultures of 4-deoxypyridoxine, a potent antagonist of vitamin B6 coenzymes, concurrently with the mitogen, inhibits the induction of serine hydroxymethyltransferase.
(19) These results suggest that prevention of xenograft rejection using PAF-antagonist in association with other methods should be further investigated.
(20) The high concentrations of gonadotropins present in immature female rats by the end of the second week of life were suppressed by treatment with an antagonist against luteinizing hormone-releasing hormone (LHRH-A; Org.
Opponent
Definition:
(a.) Situated in front; opposite; hence, opposing; adverse; antagonistic.
(n.) One who opposes; an adversary; an antagonist; a foe.
(n.) One who opposes in a disputation, argument, or other verbal controversy; specifically, one who attacks some theirs or proposition, in distinction from the respondent, or defendant, who maintains it.
Example Sentences:
(1) Certainly, Saunders did not land a single blow that threatened to stop his opponent, although he took quite a few himself that threatened his titles in the final few rounds.
(2) The odds are that Zuckerberg will one day face an opponent that can't be bought."
(3) He has also been a vocal opponent of gay marriage, appearing on the Today programme in the run-up to the same-sex marriage bill to warn that it would "cause confusion" – and asking in a Spectator column, after it was passed, "if the law will eventually be changed to allow one to marry one's dog".
(4) He is not the only jailed or exiled opponent of the CCP.
(5) After the impact … I lost my balance, making my body unstable and falling on top of my opponent,” he said in his submission to the panel, which met on Wednesday, a day after Uruguay had beaten Italy 1-0 in a decisive group-stage match.
(6) Free speech has protected hate speech, and opponents of censorship have consistantly defended the rights of unscrupulous populists and incendiarists.
(7) Arsenal’s 10 men fall at the first hurdle against Dinamo Zagreb Read more This win, even against such feeble opponents, was celebrated, with the locals chorusing their manager’s name amid a wave of relief given so much of the team’s domestic campaign to date has been dismal.
(8) The phrase “self-inflicted blow” was one he used repeatedly, along with the word “glib” – applied to his Vote Leave opponents.
(9) His teacher was the charismatic Father Matta el-Meskin (Matthew the Poor), later to become an opponent.
(10) We have to improve our playing style and beat our opponents more easily.” Van Gaal was also careful to provide an exact statement on the England full-back Luke Shaw, who suffered an ankle injury against Arsenal.
(11) In a single letter in February 2005, Charles urged a badger cull to prevent the spread of bovine tuberculosis – damning opponents to the cull as “intellectually dishonest”; lobbied for his preferred person to be appointed to crack down on the mistreatment of farmers by supermarkets; proposed his own aide to brief Downing Street on the design of new hospitals; and urged Blair to tackle an EU directive limiting the use of herbal alternative medicines in the UK.
(12) The typical balance of power on Capitol Hill over surveillance is such that opponents of renewing Section 702 face strong political headwinds.
(13) Around the same time Kadyrov said Mikhail Khodorkovsky, the former oligarch who became an opponent of Putin and now resides in Switzerland after spending a decade in prison, was now his “personal enemy”.
(14) A number of MPs and senior party figures supported a wrecking amendment that would have robbed the motion of its primary purpose, opponents said.
(15) Facebook Twitter Pinterest Trump ‘sways malevolently’ behind Hillary Clinton Instead, he began the night by assembling a group of women in a press conference to revisit alleged sexual assaults by Bill Clinton, before confronting his opponent hardest on her private email server.
(16) But what was, perhaps, even more fun than a win in the offing was that the desperation of opponents of same-sex marriage leading up to today’s argument in Obergefell v Hodges was palpable.
(17) But pipeline opponents say that by moving beetles from the Nebraska sandhills and mowing miles of grass where the insects once lived, TransCanada has illegally begun construction on the project.
(18) Despite mounting criticism during the Duma campaign, both supporters and opponents acknowledge his perceived achievement in restoring Russia's standing in the world following Boris Yeltsin's chaotic 1990s decade.
(19) These differences in hormonal responses to the fight are attributed to the more aggressive behavior displayed by the victorious opponents (winners) over their defeated competitors (losers).
(20) Koji Uehara, the one without a beard, just picked up from where he left off in the regular season, and continued to destroy opponents.