(n.) Want of feeling; privation of passion, emotion, or excitement; dispassion; -- applied either to the body or the mind. As applied to the mind, it is a calmness, indolence, or state of indifference, incapable of being ruffled or roused to active interest or exertion by pleasure, pain, or passion.
Example Sentences:
(1) In his letter Abd El Fattah highlights the arbitrary nature of many of their detentions, the torture to which thousands have probably been subjected – and the apathy towards, and often enthusiasm for, such malpractice among the public.
(2) Apathy may still be the enemy for the remain campaign, and although most of our participants, after an evening spent discussing the referendum, said they were likely to vote, they were far from certain about it.
(3) Partial and total results under the 6 factors of the questionaire: General anxiety and regression, anxiety about separation, anxiety about sleeping, eating disturbances, agressiveness against authority, apathy and isolation.
(4) The best results were observed in hebephrenic forms and depressive syndroms during the illness; in these indications, carpipramine exerts a clear psychomotor stimulating activity which is useful in decreasing indifference, apathy and ideomotor slowness.
(5) Apathy is defined as diminished motivation not attributable to diminished level of consciousness, cognitive impairment, or emotional distress.
(6) For several reasons, including public apathy, the role of interest groups, and experience with other social insurance programs, it seems likely that basic structural shifts will not occur in the near future.
(7) Other negative emotions – self-pity, guilt, apathy, pessimism, narcissism – make it a deeply unattractive illness to be around, one that requires unusual levels of understanding and tolerance from family and friends.
(8) In the mid-20th century, the customary political apathy of youth did not matter overmuch.
(9) The risk factors for incontinence were consciousness disturbance, urinary urgency, impaired mobility and dementia, and those for severe leakage were apathy, loss of urinary sensation, dementia and impaired mobility.
(10) Politicians need to deal with the problem of voter apathy in the face of statistics showing only one in 10 young people firmly intends to vote, David Blunkett , the former home secretary, has warned.
(11) Because of that, in infants with muscular hypotonia, growth arrest, constipation and apathy the possibility of idiopathic hypercalcaemia, apart from rickets, should be considered.
(12) Clinical manifestations of all three cases were severe headaches; bilateral pyramidal, pseudobulbar, cerebellar, and frontal release signs; gait disturbances; euphoria, or apathy; epileptic seizures; and dementia.
(13) Despite the handicaps of shortage of staff, lack of a broad health insurance program, and the apathy of most of the medical profession, we managed to establish a Cancer Registry that is achieving near completeness in registration of cancers at certain sites.
(14) Severe enteric colibacillosis, characterized by profuse watery diarrhea, dehydration, apathy, hypothermia, and inability to stand, was produced in seven of eight newborn, colostrum-fed calves from nonvaccinated dams after oral challenge of calves with 10(11) viable cells of Escherichia coli strain B44.
(15) Apathy, carelessness, and indifference may even increase as a by-product of technology, unless curbed by moral, ethical and legal constraints.
(16) The poll will go ahead despite fears that the turnout in the middle of August will set a new apathy record for an election.
(17) A distinction is made between cases where the gamble with death is merely consequential (i.e., arising from ignorance, apathy, indifference) and cases where it is the very essence of the act.
(18) All were chronic patients with a symptomatic profile of apathy, lack of initiative but with the personality relatively well preserved in 56 patients.
(19) The lack of information has been an issue, as well as public apathy over the new post.
(20) This results were confirmed by factorial analysis which identified three distinct clusters of symptoms: the negative syndrome (affective flattening, alogia, abolition-apathy, and anhedonia-asociality), the disorganizative syndrome (positive formal thought disorder, and attentional impairment) and the positive syndrome (delusions and hallucinations).
Opiate
Definition:
(n.) Originally, a medicine of a thicker consistence than sirup, prepared with opium.
(n.) Any medicine that contains opium, and has the quality of inducing sleep or repose; a narcotic.
(n.) Anything which induces rest or inaction; that which quiets uneasiness.
(a.) Inducing sleep; somniferous; narcotic; hence, anodyne; causing rest, dullness, or inaction; as, the opiate rod of Hermes.
(v. t.) To subject to the influence of an opiate; to put to sleep.
Example Sentences:
(1) The second experiments entailed use of the nonspecific opiate antagonist, naloxone, as well as the specific delta antagonist, ICI 154,129, against seizures induced by icv-administered morphine, morphiceptin, DADL, or DSLET.
(2) Opiate agonists and endogenous opioid peptides inhibit electrolyte secretion both in vitro and in vivo.
(3) It appears that tricyclic antidepressants act in a fashion different from opiate drugs that alter the sensory discriminative component of pain.
(4) The results are discussed with reference to the possible mechanism(s) via which injected and endogenous opiates may affect motor performance by attenuating GABA transmission in the nigra.
(5) Pharmacological data suggest that opiates, acting indirectly via the catecholaminergic system, are involved in the inhibition of LH release and the stimulation of PRL secretion.
(6) Such disturbances may be induced by opiates, benzodiazepines, phenothiazines, butyrophenones, ketamine, etomidate, propofol, nitrous oxide, and halogenated inhalation anesthetics as well as by H2-blocking agents such as cimetidine.
(7) From these results, we conclude that opiate peptides are released in response to the suckling stimulus in the cynomolgus monkey and that they mediate the effects of suckling on PRL secretion in both gonadal-intact and agonadal cynomolgus monkeys.
(8) Its potency is 4-5 times greater than that of the opiate antagonist naloxone.
(9) A cost-effective immunoassay for the detection of opiates in urine has been developed using commercial reagents on a centrifugal analyser.
(10) Drugs used to promote food intake and weight gain, such as cyproheptadine, amitriptyline, clonidine and opiate antagonists, have provided disappointing results.
(11) An alternative approach, which correlates the structure-activity data of opiate compounds with that of the enkephalins, is described and shown to produce a model consistent with the available structure-activity data.
(12) However, opiate treatment is not a new therapeutic concept in psychiatry.
(13) The inhibitory response was not decreased by treatment with atropine, hexamethonium, yohimbine or naloxone, suggesting that muscarinic, nicotinic, alpha 2 adrenergic or opiate receptors were not being stimulated.
(14) The hypothesis that opiate agonism requires an N substituent in the axial position does not appear to be consistent with the increased potency of beta isomers in which axial N substituents are thermodynamically more unstable.
(15) We report that exposure of rat spinal cord-dorsal root ganglion cocultured neurons to kappa-opiate agonist is accompanied by a 60-70% reduction in the level of the alpha i subunit of GTP-binding proteins.
(16) Cerebrospinal fluid (CSF) opiate activity has been found to be elevated in two studies.
(17) PBEir increased with both opiates immediately after initiation of CPB and remained so during the rest of the study.
(18) Diclofenac is an alternative to opiates in the management of postoperative pain.
(19) On the other hand, if the tissue-derived opiates were from prodynorphin, only Leu-enkephalin should be found.
(20) Analysis of patient questionnaires suggests more enthusiasm for patient-controlled analgesia, but in this study, it was difficult to clearly demonstrate any significant advantage for pain management or amount of opiate administered.