(1) The presence of proteins antigenically related to Bothrops asper myotoxins in various snake venoms, mainly from South America, was investigated by using polyclonal and monoclonal antibodies.
(2) The myotoxin shows partial immunologic identity with a myotoxic phospholipase A2 isolated from Bothrops asper venom.
(3) Mice that received antivenom (0.4 ml) by the iv or im route 15 min after im injection of B. asper venom (100 micrograms) had lower levels of plasma anti-myotoxin antibodies than controls injected with antivenom only, suggesting that at least a fraction of the antibodies combines with myotoxins in vivo.
(4) Metalloproteinase from the venom of Bothrops asper (proteinase G) is a glycoprotein with 1% neutral hexose and 3.5 moles of sialic acid per mole of protein.
(5) A new instrumentation for posterior spinal surgery consists of metallic rods carved with diamond-shaped asperities on which vertebral hooks or screws can be screwed in any position, level, or degree of rotation.
(6) Conditions that inhibited phospholipase A2 activity, i.e., substitution of calcium by EDTA, reduced liposome-disrupting activity of Bothrops asper myotoxin I and Bothrops atrox myotoxin, both of which have high phospholipase A2 activity, but did not affect the action of B. asper myotoxin II and Bothrops moojeni myotoxin II, which have extremely low phospholipase A2 activity.
(7) The time-course and composition of inflammatory infiltrate in mouse gastrocnemius injected with Bothrops asper venom was studied.
(8) Also, the organization of these asperities is directly related to cellular cytoskeletal elements.
(9) The neutralization of two myotoxic phospholipases A2 from the venom of Bothrops asper, myotoxins I and II, by two murine monoclonal antibodies is reported.
(10) Seventeen batches of ICP antivenom were analyzed by EIA, using B. asper myotoxin II as antigen.
(11) No major differences in the DNase electrophoretic pattern were observed between individual venoms of adult B. asper specimens nor between lyophilized and frozen venoms.
(12) It is suggested that muscle regeneration is partially impaired after myonecrosis induced by Bothrops asper venom, probably due to the damage induced by this venom on muscle microvasculature and nerves.
(13) He used fine needle asperation or scraping of pathological tissue and hematoxylin-eosin staining of smears.
(14) Immunochemical results indicate a close immunological relationship between venoms of B. asper, B. nummifer and C. d. durissus collected in Honduras and Guatemala with those of the same species collected in Costa Rica.
(15) A new muscle damaging toxin, myotoxin II, was purified from the venom of Bothrops asper by ion-exchange chromatography on CM-Sephadex C-25.
(16) Ouchterlony immunodiffusion analysis of purified antibodies showed two precipitation bands with a pattern of complete immunologic identity between samples of crude B. asper venoms from specimens collected in the Atlantic and Pacific regions of Costa Rica.
(17) Myotoxin is an abundant component in adult B. asper venom.
(18) Five polyvalent antivenoms (Crotalidae; Orient, North, Central and South Africa) were tested for their ability to neutralize the thrombin-like activity of snake venoms (Bitis gabonica, Agkistrodon acutus, Bothrops asper, B. atrox, Crotalus adamanteus).
(19) A myotoxic, basic phospholipase A2 (pI greater than 9.5) with anticoagulant activity has been purified from the venom of Bothrops asper, and its amino acid sequence determined by automated Edman degradation.
(20) The effects of a myotoxic phospholipase A2 isolated from the venom of the crotaline snake Bothrops asper on skeletal muscle myofibrils were studied by histological, ultrastructural, immunohistochemical, and biochemical parameters.
Bitter
Definition:
(n.) AA turn of the cable which is round the bitts.
(v. t.) Having a peculiar, acrid, biting taste, like that of wormwood or an infusion of hops; as, a bitter medicine; bitter as aloes.
(v. t.) Causing pain or smart; piercing; painful; sharp; severe; as, a bitter cold day.
(v. t.) Causing, or fitted to cause, pain or distress to the mind; calamitous; poignant.
(v. t.) Characterized by sharpness, severity, or cruelty; harsh; stern; virulent; as, bitter reproach.
(1) Since the election on 7 March there has been a bitter contest for power in Iraq led by Iran, Saudi Arabia and Turkey.
(2) If bitter, pour it out and measure 1.4 litres of water.
(3) The dumplings could also be served pan-fried in browned butter and tossed with a bitter leaf salad and fresh sheep's cheese for a lighter, but equally delicious option.
(4) The first was a passive avoidance task in which the chicks were allowed to peck at a green training stimulus (a small light-emitting diode, LED) coated in the bitter liquid, methylanthranilate, giving rise to a strong disgust response and consequent avoidance of the green stimulus.
(5) In the QHCl-sucrose condition components separated by the tongue's midline and those spatially mixed produced equal amounts of bitterness suppression.
(6) At the interview those with conventional ileostomies expressed better preoperative comprehension of the procedure and more satisfaction about its life-saving nature; nevertheless, they experienced more negative emotional reactions, such as bitterness, after the operation.
(7) The higher analogues of the cycloalkane series containing alpha-aminocycloheptanecarboxylic acid methyl ester and alpha-aminocyclooctanecarboxylic acid methyl ester are bitter.
(8) It's almost starting to feel like we're back in the good old days of July 2005, when Paris lost out to London in the battle to stage the 2012 Olympic Games, a defeat immediately interpreted by France as a bitter blow to Gallic ideals of fair play and non-commercialism and yet another undeserved triumph for the underhand, free-market manoeuvrings of perfidious Albion.
(9) Hollande ended up defending until to the bitter end Jérôme Cahuzac , a finance minister responsible for fighting tax evasion who turned out to have used a secret Swiss bank account to avoid paying taxes in France.
(10) The sensitivity of the taste system to the various qualities was, in decreasing order, salty, sweet, sour, and bitter.
(11) Grace's ascent has also thrown a grenade into the bitter succession battle within Zanu-PF, which Mugabe has divided and ruled for decades.
(12) Denatonium, a very bitter substance, caused a rise in the intracellular calcium concentration due to release from internal stores in a small subpopulation of taste cells.
(13) I see myself in exactly the same situation as I saw myself yesterday, though obviously with the bitter disappointment of the failure of being knocked out.
(14) Stephen Joseph, its chief executive said: "This is bitter news for everyone who relies on the train to get to work, not least the large number of commuters in marginal constituencies who will be a key group at the next election."
(15) Lewis Wind Power, the joint venture company set up by Amec and British Energy, said it was "bitterly disappointed" by the decision.
(16) As night fell in Paris, despite the bitter cold, more than 5,000 people gathered under the imposing statue of Marianne, the symbol of the republic, to show their anger, grief and solidarity.
(17) The present alternative model of health care in China has evolved after prolonged and often bitter debate extending over twenty years.
(18) It is much less soluble and bitter and poses few stability problems when capsulated or tableted with aspirin.
(19) "They have given Mexicans the most bitter Christmas," Armando Martínez, the president of the College of Catholic Attorneys, told reporters.
(20) He says he is not bitter but his words are laced with hostility.