(superl.) Wanting good qualities, whether physical or moral; injurious, hurtful, inconvenient, offensive, painful, unfavorable, or defective, either physically or morally; evil; vicious; wicked; -- the opposite of good; as, a bad man; bad conduct; bad habits; bad soil; bad health; bad crop; bad news.
() of Bid
Example Sentences:
(1) City badly missed Yaya Touré, on international duty at the Africa Cup of Nations, and have not won a league match since last April when he has been missing.
(2) For viewers in the US, you get the worst possible in-game managerial interview in Mike Matheny, one that's so bad, it's actually great!
(3) Former lawmaker and historian Faraj Najm said the ruling resets Libya “back to square one” and that the choice now faced by the Tobruk-based parliament is “between bad and worse”.
(4) In London, diesel emissions are now so bad that on several days earlier this summer, children, older people and vulnerable adults were warned not to venture outside .
(5) Following mass disasters and individual deaths, dentists with special training and experience in forensic odontology are frequently called upon to assist in the identification of badly mutilated or decomposed bodies.
(6) "Seller reports are key to identifying bad buyers and ridding them from our marketplace," says eBay.
(7) Botswana, Kenya, Somalia and the Democratic Republic of the Congo have also been badly hit.
(8) We are better off in.” Out campaigners have claimed that the NHS could be badly hit by a decision to stay in the EU.
(9) However, the City focused on the improvement in the fortunes of its Irish business, Ulster bank, and its new mini bad bank which led to a 1.8% rise in the shares to 368p.
(10) Urban hives boom could be 'bad for bees' What happened: Two professors from a University of Sussex laboratory are urging wannabe-urban beekeepers to consider planting more flowers instead of taking up the increasingly popular hobby.
(11) Pupils who disrupt the learning of their classmates are dealt with firmly and, in many cases, a short suspension is an effective way of nipping bad behaviour in the bud."
(12) On a weekend that sees the country celebrate 50 years of independence it is certain that despite all things – good and bad – that have taken place in 2013, the next 50 years will be transformed by personal technology, concerned citizens and the media.
(13) Meanwhile the Brooklyn Nets, who have been dealing with nothing but bad news since the start of the regular season, will be without Paul Pierce for 2-4 weeks, also due to a right hand fracture.
(14) It's bad enough that they're so thin,” said Kilbourne.
(15) "I am in a bad situation, psychologically so bad and confused," one father said, surrounded by his three other young sons.
(16) Later, Lucas, also a former party leader, strongly defended Bennett, saying it was a “bad day for Natalie” but there was also “kind of a gloating tone that strikes one as having something to do with her being a woman in there too”.
(17) Another five years of Tory rule with all the terrible consequences that will have is bad enough.
(18) We suggest that sick districts can be affirmed on the basis of the total amount of fluoride intake, the prevalence rates of dental fluorosis, bad incomplete teeth, milk-teeth and the mean output of urinary fluoride between 8 and 15 years of age.
(19) Two hundred forty-six fetuses had at least one abnormal biophysical profile variable with the risk of bad outcome, for a single abnormal variable, ranging from 8% (body movements) to 100% (tone) and increasing from 14% (any variable abnormal) to 63% (all variables abnormal).
(20) This is bad constitutional reform, but it is a reform anyway.
Fad
Definition:
(n.) A hobby ; freak; whim.
Example Sentences:
(1) Either reagent dislocates FAD from the holoenzyme, leaving a characteristic mercaptide derivative of the apoenzyme.
(2) After restrained least-squares refinement of the enzyme-substrate complex with the riboflavin omitted from the model, additional electron density appeared near the pyrophosphate, which indicated the presence of an ADPR molecule in the FAD binding site of PHBH.
(3) RR spectra of fatty acyl-CoA and its complexes are consistent with the previous hypothesis that visible spectral shifts observed during formation of acetoacetyl-CoA and crotonyl-CoA complexes of fatty acyl-CoA dehydrogenase result from charge-transfer interactions in which the ground state is essentially nonbonding as opposed to interactions in which complete electron transfer occurs to form FAD semiquinone.
(4) Her full name is Kitty White, and she has a family and lives in London (due to a Japanese fad for all things British in the mid-1970s).
(5) D-Amino acid oxidase purified from the yeast Rhodotorula gracilis is a flavoenzyme which does not require exogenous FAD for maximum activity.
(6) Flavin adenine dinucleotide (FAD) was covalently attached to an electron-conducting support, i.e., glassy carbon.
(7) Transient kinetic analysis for the interaction of MCAD-FAD with IACoA suggests that the formation of the enzyme-IACoA complex proceeds in two steps.
(8) Alignment of these sequences with that of squash defines domains of nitrate reductase that appear to bind its 3 prosthetic groups (molybdopterin, heme-iron, and FAD).
(9) With so many superfoods jostling for attention in the media and on supermarket shelves, it’s not always easy to separate the fad from the genuinely healthy.
(10) The depth of FAD incorporation into the enzyme molecule as calculated according to the outer sphere electron transfer theory is 6.1 A.
(11) The half-life of the solubilized oxidoreductase stored at 2-4 degrees C in the presence of 25% glycerol at pH 8.6 is approximately 30 h. The oxidoreductase contains a flavoprotein identifiable by its fluorescence spectrum for FAD which binds weakly to concanavalin A-Sepharose and elutes from gel sieving columns at a molecular weight range of approximately 51,000.
(12) Lifetime risk of dementia in early-onset FAD kindreds is consistent with an autosomal dominant inheritance model.
(13) Thus, ETF appears to contain one flavin (at least 90% FAD, by chromatographic and fluorescence characteristics) per 26,000 M-r, and therefore may be composed of two subunits with one flavin each.
(14) Microcoulometric titrations of NADH:nitrate reductase at 25 degrees C in Mops buffer, pH 7.0, showed that the native enzyme, containing functional FAD, haem and Mo, required addition of five electrons for complete reduction.
(15) An automated AutoAnalyzer method using 5:5'-dithiobis-2-nitrobenzoic acid is described for determining whole blood glutathione reductase (BGR) activity and for measuring in vitro activation of BGR with flavin adenine dinucleotide (FAD).
(16) The kinetic course of the reaction of methanol and deutero-methanol with FAD-dependent alcohol oxidase was investigated under single-turnover conditions [kred approximately equal to 15000 min-1 (1H3COH) and approximately equal to 4300 min-1 (2H3COH)] and multiple-turnover conditions [TNmax approximately equal to 6000 min-1 (1H3COH) and approximately equal to 3100 min-1 (2H3COH)].
(17) It had been shown that thyroxine regulates the conversion of riboflavin to riboflavin mononucleotide and flavin adenine dinucleotide (FAD) in laboratory animals.
(18) The value of P of the enzyme is dependent on its concentration, indicating that the degrees of dissociation of FAD in the monomer and dimer are different.
(19) We now provide evidence for a major early onset FAD locus on the long arm of chromosome 14 near the markers D14S43 and D14S53 (multipoint lod score z = 23.4) and suggest that the inheritance of FAD may be more complex than had initially been suspected.
(20) Thus, the low activity resulting from an inherited deficiency of FAD is decreased further.