(n.) A carpentry obstruction, stockade, or other obstacle made in a passage in order to stop an enemy.
(n.) A fortress or fortified town, on the frontier of a country, commanding an avenue of approach.
(n.) A fence or railing to mark the limits of a place, or to keep back a crowd.
(n.) An any obstruction; anything which hinders approach or attack.
(n.) Any limit or boundary; a line of separation.
Example Sentences:
(1) Here we have asked whether protection from blood-borne antigens afforded by the blood-brain barrier is related to the lack of MHC expression.
(2) We conclude that chloramphenicol resistance encoded by Tn1696 is due to a permeability barrier and hypothesize that the gene from P. aeruginosa may share a common ancestral origin with these genes from other gram-negative organisms.
(3) The findings clearly reveal that only the Sertoli-Sertoli junctional site forms a restrictive barrier.
(4) This suggests that a physiological mechanism exists which can increase the barrier pressure to gastrooesophageal reflux during periods of active secretion of the stomach, as occurs in digestion.
(5) Comparison of the 50% binding concentrations of the compounds for the various PBPs of the five strains with their antibacterial activity indicates that the different antibiotics are excluded to a greater or lesser degree by the outer membrane permeability barrier and that the exclusion is most pronounced in P. aeruginosa.
(6) Preservation of dopaminergic and H1 neurotransmission, probably within the blood barrier, is needed to allow the neuroendocrine transduction of cholinergic inputs, whereas the role of 5-HT neurotransmission remains uncertain.
(7) Their levels in urine are a useful indicator of the integrity of membrane barriers of the kidney glomerular capillary wall.
(8) The IgG index (formula: see text) corrects for the influence of serum protein abnormalities as well as a bloodbrain barrier damage and is, therefore, a better measure for the presence of an IgG elevation in CSF due to IgG synthesis, when compared with other IgG quotients commonly used.
(9) In the far east is the arid, depressed country leading down Hell’s Canyon, which bottoms out at the Snake River, which the wolves crossed when they moved from Idaho, and which they now treat more as a crosswalk than a barrier.
(10) No signs of the blood-brain barrier disruption were observed.
(11) Although no anatomical 'barrier' has been described, it has been suggested that the gel mucus and epithelial phospholipids are constituents.
(12) Despite their wide dispersion, Vmax and the stereological determinations correlated strongly at 2 mo of age, confirming that Vmax is a robust indicator of the surface area of the air-blood barrier.
(13) Developmental changes are delineated, with particular reference to recent work on the ovine blood-brain barrier.
(14) Features of barrier island physiography and ecology were studied relative to selective bait deployment and site biosecurity.
(15) This study sought to determine if and why barriers to the over-the-counter purchase of syringes in the St. Louis metropolitan area might exist, given that no ordinance prohibits such a sale there.
(16) It is suggested that the intercalated disc functioned as a barrier to the freezing process.
(17) To explain some of these results a theoretical model is presented to demonstrate that while short circuiting can block the passive ionic movement, it will cause an increase in the energy consumption of the system and introduce certain important changes in the ionic barriers and e.m.fs.
(18) Our results show that paramagnetic enhancement with T1-weighted imaging adds specificity and enables rapid assessment of abnormalities of the blood-brain barrier.
(19) A functional impairment of the amino acid transport systems at the level of the blood-brain barrier seems to play a crucial role in causing deleterious modifications of the synaptic neurotransmission in the central nervous system.
(20) There was a significant correlation between the lesion index and the PD reduction, although the integrity of the resting gastric mucosal barrier remained unaltered.
Hinder
Definition:
(a.) Of or belonging to that part or end which is in the rear, or which follows; as, the hinder part of a wagon; the hinder parts of a horse.
(a.) To keep back or behind; to prevent from starting or moving forward; to check; to retard; to obstruct; to bring to a full stop; -- often followed by from; as, an accident hindered the coach; drought hinders the growth of plants; to hinder me from going.
(a.) To prevent or embarrass; to debar; to shut out.
(v. i.) To interpose obstacles or impediments; to be a hindrance.
Example Sentences:
(1) The blocking action may have masked and hindered detection of the stimulatory action of barium in other systems.
(2) Diffusional anisotropy of water protons, induced by nonrandom, directional barriers which hinder or retard water motion, is measurable by MRI.
(3) The power of the landed elite is often cited as a major structural flaw in Pakistani politics – an imbalance that hinders education, social equality and good governance (there is no agricultural tax in Pakistan).
(4) Mapping of susceptibility is hindered by the limitations of conventional tissue typing techniques, and by strong linkage disequilibrium within this part of the genome.
(5) From these results, we presume that light induces a protein that hinders the interaction of gp70 in HM1 cells with its receptor on the NC4 cell surface and thereby inhibits the sexual process between these strains.
(6) This in vivo incorporation of tungsten was competitively hindered by molybdenum.
(7) If a prisoner is in the process of taking a programme this can hinder or even curtail their progress – many prisons don't offer certain programmes so if you are moved to a prison without a particular course you are back to square one when it comes to the crucial Parole Board assessment.
(8) From the outset the former Leicester University economics professor has made no secret of the fact this his “dysfunctional relationship” with Anastasiades and other central Bank board members had hindered his role in the post.
(9) The inhibition of Na+K+ ATPase and Mg2+ ATPase activity which may affect the release and uptake of biogenic amines in CNS, hinders the maturation of human fetal brain.
(10) The identification of patients usually refractory to outpatient treatment was hindered by the constant flux in the population base as illustrated by an 85% increase in the asthma registry over the succeeding 12-mo period.
(11) OKT4 and OKT8 monoclonal antibodies slightly hindered depolarization by CsA while OKT3, OKT11 and OKIa1 antibodies had no such effect.
(12) The Communist party and the liberal Yabloko party complained on Sunday of extensive election violations aimed at boosting United Russia's vote count, including party observers being hindered in their work.
(13) These data indicate that the basic model presented here provides a suitable vehicle for future studies into the biochemical events that may cause skeletal muscle enlargement during resistance training but, based on limited data, suggests that an increased frequency of training days may hinder muscle enlargement in this model.
(14) If this geometry was changed, a decrease in affinity was observed and if the ligand binding was sterically hindered, a spectral shift to a five-coordinated complex absorbing at 390 nm occurred.
(15) Administrative inefficiency hinders even more the appropriate utilization of resources.
(16) Thus, the product of natural processing of equine myoglobin probably has hindering structures in the regions flanking the core epitope 102-118 that interfere with presentation by I-Ak but not I-AS.
(17) Many tropical diseases cause disability and hinder the socio-economic development of the Third World countries where they rage.
(18) The difficulties encountered in casting titanium and its alloys have until recently hindered any widespread use of titanium in restorative dentistry.
(19) Warming water will make it hard for many of the reef’s corals to survive, while the acidification of the oceans will hinder the ability of remaining corals to form their skeletons.
(20) The 3-nitrocatechol-structure of nitecapone seems to hinder nitro-reduction, catechol-O-methylation, and sulfation reactions.