(n.) The foundation of anything; that on which a thing rests.
(n.) The pedestal of a column, pillar, or statue.
(n.) The ground work the first or fundamental principle; that which supports.
(n.) The principal component part of a thing.
Example Sentences:
(1) Arachidic acid was without effect, while linoleic acid and linolenic acid were (on a concentration basis) at least 5-times less active than arachidonic acid.
(2) The combined analysis of pathogenesis and genetics associated with the salmonella virulence plasmids may identify new systems of bacterial virulence and the genetic basis for this virulence.
(3) On the basis of 180 interventions, they describe in detail the use of fibrin glue in myringo- and tympanoplasty for correct fixing of grafts.
(4) For the first time it was organized on the basis of population.
(5) The purpose of these studies was to better understand the molecular basis of chromosome aberration formation after mitomycin C treatment.
(6) Acquired drug resistance to INH, RMP, and EMB can be demonstrated in M. kansasii, and SMX in combination with other agents chosen on the basis of MIC determinations are effective in the treatment of disease caused by RMP-resistant M. kansasii.
(7) A novel prostaglandin E2 analogue, CL 115347, can be administered transdermally on a long-term basis.
(8) In this phase the educational practices are vastly determined by individual activities which form the basis for later regulations by the state.
(9) The structures of 1 and 2 were established mainly on the basis of nmr spectroscopic data.
(10) Determination of the primary structure for factor V has provided the basis for examination of structure-function relationships.
(11) The Bohr and Root effects are absent, although specific amino acid residues, considered responsible of most of these functions, are conserved in the sequence, thus posing new questions about the molecular basis of these mechanisms.
(12) On the basis of obtained data on the uniformity of chemical compounds of the secretion of glands belonging to different groups their common origin has been suggested.
(13) The stepped approach is cost-effective and provides an objective basis for decisions and priority setting.
(14) On the basis of primary sequence homology with other known Pseudomonas lipases, a number of putative active site residues located in conserved areas were found.
(15) If, indeed, there is an immunologic basis for pre-eclampsia, it is more subtle than the methodology used in this study is capable of detecting.
(16) "These developments are clearly unwarranted on the basis of economic and budgetary fundamentals in these two member states and the steps that they are taking to reinforce those fundamentals."
(17) On the basis of mathematical models of the obtained dose-time-effect relationship, the risk of cancer occurrence due to small carcinogen doses is predicted.
(18) The relatively high incidence of nephroblastoma in the Nb rat using transplacentally administered ENU appears to represent a suitable basis for developing a rodent model of human nephroblastoma or Wilms' tumor.
(19) In this study we investigated the recovery or regenerative process of nasal mucosa in rabbits after mechanical injury on the basis of ultrastructural as well as functional observations.
(20) Three distinct antigenic regions of bovine somatotropin (bST) were identified on the basis of the ability of a set of monoclonal antibodies to bind to proteolytic fragments and deletion variants of recombinant bST (rbST) in Western blot analyses.
Underlie
Definition:
(v. t.) To lie under; to rest beneath; to be situated under; as, a stratum of clay underlies the surface gravel.
(v. t.) To be at the basis of; to form the foundation of; to support; as, a doctrine underlying a theory.
(v. t.) To be subject or amenable to.
(v. i.) To lie below or under.
(n.) See Underlay, n., 1.
Example Sentences:
(1) The A2 channels have a conductance of 6-8 pS and underlie the whole-cell A current.
(2) The data could indicate that abnormalities of dopamine metabolism may underlie both the motor and mental abnormalities of Parkinsonism.
(3) The polygenic control of diabetogenesis in NOD mice, in which a recessive gene linked to the major histocompatibility complex is but one of several controlling loci, suggests that similar polygenic interactions underlie this type of diabetes in humans.
(4) Recombinant DNA studies have clarified the genetics that underlie neurofibromatosis type 2 and separate it from a variety of related conditions, such as von Recklinghausen's neurofibromatosis.
(5) X-ray analysis of these crystals will permit direct visualization of the specific structural motifs and chemical features that underlie phospholipase neurotoxicity.
(6) The resolution of the cellular events which underlie the development of pancreatitis in combination with the introduction of new therapeutic agents may enable a rational and safe protocol to be developed for the support of patients with pancreatitis.
(7) These channels underlie the graded active responses that can be elicited at the offset of abrupt hyperpolarizing and depolarizing intracellular current pulses.
(8) By relating muscle activity with sound production , such bursting was shown to underlie evoked vocalizations.
(9) A voltage-dependent, fast inactivating outward current may underlie these responses.
(10) Looking at an old problem from a new perspective can sometimes lead to new ways of analyzing experimental data which may help in understanding the mechanisms that underlie the phenomena.
(11) It is hypothesized that somewhat different mechanisms underlie recovery in neonatal and adult operated animals.
(12) Thus, the avidity measurement is useful in understanding the immunological events which underlie various clinicopathological features of SLE.
(13) Mast cell degranulation of histamine may partly underlie the appearance of increased amounts of hyaluronan in lavage fluid from patients with interstitial lung diseases and allergic asthma.
(14) Because available evidence suggests that alterations in the serotonergic as well as dopaminergic tones underlie hallucinatory activity, we decided to investigate whether serotonin and dopamine pathways are modified in alcoholics with a history of hallucinosis.
(15) We hypothesize that sampling-induced decreases in steady-state ADOi underlie these observations, because losses of ISF adenosine to high volumes of sample buffer can be greater than the myocardial cells are capable of replacing.
(16) The reactive synaptogenesis that takes place in the rat hippocampal formation after certain experimental manipulations affords an opportunity to investigate the molecular events that underlie structural remodeling in the adult CNS.
(17) Changing patterns of DNA methylation may underlie differential gene expression in development.
(18) LTP in these two structures could underlie their role in memory consolidation and could explain the late involvement of the entorhinal cortex in post-training memory processing.
(19) We suggest that in hairy cell leukaemia both monocytopenia and defective functions of monocytes underlie the increased susceptibility to intracellular infections including Legionnaires' disease.
(20) Activity-dependent changes in synaptic efficacy may underlie the acquisition of memory.