(1) Recent data suggest that administering cimetidine 800 mg at bedtime has less effect on the serum concentrations of warfarin and theophylline than other dosing regimens.
(2) Miconazole nitrate was administered once daily, at bedtime, for 14 days to 55 pregnant and non-pregnant patients.
(3) The evening before the ACTH test, each subject took dexamethasone (1 mg at bedtime) to suppress the early morning surge of ACTH.
(4) Thirty-nine patients whose endoscopic lesions improved were then randomized to a ten-month maintenance regimen of either cimetidine 400 mg at bedtime or placebo.
(5) The effect of a single, oral bedtime dose of the benzodiazepine hypnotics flunitrazepam (FR; 2 mg), flurazepam (FR; 30 mg), and triazolam (TR; 0.5 mg) on the sleep stages and the sleep EEG was investigated in eight healthy, young subjects.
(6) Dosing in the double-blind trials was 100 mg at bedtime, but in open-label trials patients could increase the dosage of nabumetone to 1500 or 2000 mg if required.
(7) Recently, the use of bedtime NPH or ultralente insulin has been emphasized for control of moderate hyperglycemia in these patients.
(8) Chlorthalidone was changed to bedtime administration and taken with the study medications.
(9) One hundred sixty-two patients chronically ingesting ibuprofen, piroxicam, or naproxen for osteoarthritis, who had abdominal pain and an endoscopically proven gastric ulcer were evaluated for eight weeks in a randomized, double-blind trial comparing misoprostol (200 micrograms four times daily with meals and at bedtime) (N = 77) with placebo (N = 85).
(10) Thirty-two women with recurrent urinary tract infections were treated after eradication of existing infections with a mixture of 40 mg of trimethoprim and 200 mg of sulfamethoxazole thrice weekly at bedtime for six months.
(11) Although trazodone therapy has been associated with lethargy, dizziness, drowsiness, and confusion in some patients, symptoms have been mild and can be further minimized by administering the drug either after meals or once daily at bedtime.
(12) The author compares the efficacy of ranitidine 300 mg in a single bedtime dose, and ranitidine 150 mg twice daily, in 509 duodenal ulcer patients treated in two Italian multicentre trials.
(13) Eight factors were investigated as possible correlates of percentage REM sleep and of total minutes of REM sleep: age, height, weight, bedtime, arising time, oral temperature at bedtime and on arising, and total sleep time.
(14) In the first two weeks of life rectal temperature changed little overnight, but by 6 weeks of age rectal temperature at bedtime was significantly higher than later in the night.
(15) Treatment consisted of daily coal tar emulsion baths at bedtime, followed by the application of 0.05 percent diflorasone diacetate ointment.
(16) 120 adult outpatients with endoscopically proven duodenal ulcer were randomly allocated to three groups of 40, treated in a double-blind manner with cimetidine 400 mg twice daily, trimoprostil 3 mg twice daily and trimoprostil 3 mg at bedtime.
(17) Bedtime dosing of hydroxyzine was investigated as a dosing strategy to minimize reaction time degradation and adverse subjective symptoms previously documented for hydroxyzine in divided doses.
(18) Psychiatric patients on multiple-dosage schedules reported no more frightening dreams than the medical patients, whereas almost three-fourths of those receiving single bedtime doses had frightening dreams, a significant difference from the medical sample.
(19) The results of this study demonstrated that nabumetone, 1,000 mg at bedtime, is as efficacious as aspirin, 900 mg four times daily, produces fewer adverse effects, and is indicated in the treatment of osteoarthritis.
(20) A randomized controlled trial was carried out to compare the efficacy of conventional 400 mg twice daily dose of cimetidine with single bedtime 800 mg dose, in 40 patients with endoscopically proven duodenal ulcer.
Time
Definition:
(n.) Duration, considered independently of any system of measurement or any employment of terms which designate limited portions thereof.
(n.) A particular period or part of duration, whether past, present, or future; a point or portion of duration; as, the time was, or has been; the time is, or will be.
(n.) The period at which any definite event occurred, or person lived; age; period; era; as, the Spanish Armada was destroyed in the time of Queen Elizabeth; -- often in the plural; as, ancient times; modern times.
(n.) The duration of one's life; the hours and days which a person has at his disposal.
(n.) A proper time; a season; an opportunity.
(n.) Hour of travail, delivery, or parturition.
(n.) Performance or occurrence of an action or event, considered with reference to repetition; addition of a number to itself; repetition; as, to double cloth four times; four times four, or sixteen.
(n.) The present life; existence in this world as contrasted with immortal life; definite, as contrasted with infinite, duration.
(n.) Tense.
(n.) The measured duration of sounds; measure; tempo; rate of movement; rhythmical division; as, common or triple time; the musician keeps good time.
(v. t.) To appoint the time for; to bring, begin, or perform at the proper season or time; as, he timed his appearance rightly.
(v. t.) To regulate as to time; to accompany, or agree with, in time of movement.
(v. t.) To ascertain or record the time, duration, or rate of; as, to time the speed of horses, or hours for workmen.
(v. t.) To measure, as in music or harmony.
(v. i.) To keep or beat time; to proceed or move in time.
(v. i.) To pass time; to delay.
Example Sentences:
(1) In April, they said the teenager boarded a flight to Turkey with his friend Hassan Munshi, also 17 at the time.
(2) Neuromedin B (C50 6 x 10(-12) M) was 3 times less potent than bombesin-14.
(3) Since fingernail creatinine (Ncr) reflects serum creatinine (Scr) at the time of nail formation, it has been suggested that Ncr level might represent that of Scr around 4 months previously.
(4) Herpesviruses such as EBV, HSV, and human herpes virus-6 (HHV-6) have a marked tropism for cells of the immune system and therefore infection by these viruses may result in alterations of immune functions, leading at times to a state of immunosuppression.
(5) In contrast, resting cells of strain CHA750 produced five times less IAA in a buffer (pH 6.0) containing 1 mM-L-tryptophan than did resting cells of the wild-type, illustrating the major contribution of TSO to IAA synthesis under these conditions.
(6) For some time now, public opinion polls have revealed Americans' strong preference to live in comparatively small cities, towns, and rural areas rather than in large cities.
(7) The proportion of motile spermatozoa decreased with time at the same rate when samples were prepared in either HEPES or phosphate buffers.
(8) Arachidic acid was without effect, while linoleic acid and linolenic acid were (on a concentration basis) at least 5-times less active than arachidonic acid.
(9) Van Persie's knee injury meant that Mata could work in tandem with the delightfully nimble Kagawa, starting for the first time since 22 January.
(10) Cantact placing reaction times were measured in cats which were either restrained in a hammock or supported in a conventional way.
(11) We conclude that first-transit and blood-pool techniques are equally accurate methods for determining EF when the time-activity method of analysis is employed.
(12) The effects of sessions, individual characteristics, group behavior, sedative medications, and pharmacological anticipation, on simple visual and auditory reaction time were evaluated with a randomized block design.
(13) An effective graft-surveillance protocol needs to be applicable to all patients; practical in terms of time, effort, and cost; reliable; and able to detect, grade, and assess progression of lesions.
(14) At the early phase of the sensitization a T-cell response was seen in vitro, characterized by an increased spleen but no peripheral blood lymphocyte reactivity to T-cell mitogens at the same time as increased reactivity to the sensitizing antigen was detected.
(15) The HBV infection was tested by the reversed passive hemagglutination method for the HBsAg and by the passive hemagglutination method for the anti-HBs at the time of recruitment in 1984.
(16) ), the concentration of AMPO in the hypothalamus was 5.4 times the concentration at 20 h after one injection.
(17) Trifluoroacetylated rabbit serum albumin was 5 times more reactive with these antibodies and thus more antigenic than the homologous acetylated moiety confirming the importance of the trifluoromethyl moiety as an epitope in the immunogen in vivo.
(18) The time of observation varied between 2 and 17 years.
(19) Lp(a) also complexes to plasmin-fibrinogen digests, and binding increases in proportion to the time of plasmin-induced fibrinogen degradation.
(20) The extent of the infectious process was limited, however, because the life span of the cultures was not significantly shortened, the yields of infectious virus per immunofluorescent cell were at all times low, and most infected cells contained only a few well-delineated small masses of antigen, suggestive of an abortive infection.