(1) P1,P2-Bidentate Cr(H2O)4PPS and Co(NH3)4PPS (prepared from PPS) were both found to be substrates for PPase.
(2) The beta, gamma-bidentate of chromium(III)ATP (Kd = 8 microM) had a higher than the alpha, beta, gamma-tridentate of chromium(III)ATP (Kd = 44 microM) or the cobalt tetramine complex of ATP (Kd = 500 microM).
(3) Hexadentate ligands would be preferable to bidentate compounds but no suitable compounds are available.
(4) PPase was unable to catalyze the hydrolysis of Mg(H2O)4PNP and P1,P2-bidentate Co(NH3)4PNP under conditions that resulted in rapid hydrolysis of the corresponding metal-PPi complexes.
(5) It is proposed that all of the anions behave as bidentate ligands, with coordination to the iron through both the carboxylate and proximal groups, and the carboxyl group serves as a bridge between the iron and a positively charged group on the protein.
(6) Paramagnetic effects of beta,gamma-bidentate Cr3+ATP on the longitudinal relaxation rates of protons of the peptide provided a set of distances to the side chains of five residues, which allowed the location of the bound Cr3+ atom to be uniquely defined.
(7) It is most likely that one C126 per subunit provides high-avidity bidentate ligation to Hg(II), but it remains possible that C82 may be a secondary Hg(II) ligand (e.g., in a tetracoordinate thiol ligation array).
(8) Mass spectrometry and 1H-NMR indicated that the (d,l-trans-1,2-diaminocyclohexane)methionineplatinum(II) complexes that formed in RPMI-1640 medium consisted of approximately 60% of the bidentate mono-methionine complex coordinated to platinum at the sulfur and alpha-amino positions and 40% of the bis-methionine complex, presumably coordinated at the sulfurs.
(9) Spectroscopic and other evidence indicated that the sugar anions bind monodentately in trans-[PtL2(NH3)2].H2O and bidentately in cis-[PtL(NH3)2]L.H2O complexes through the carboxylate oxygen atoms and other sugar donor groups.
(10) The ability of beta, gamma-bidentate CrATP to act as a substrate (Danenberg and Cleland [1975].
(11) The chromium moiety of gamma,beta-bidentate CrATP slowly accepts a ligand from the sarcoplasmic reticulum Ca-ATPase to form an exchange inert coordination complex (k + 1 = 0.083 min-1; k - 2 = 0.003 min-1, 37 degrees C, 100 microM CaCl2).
(12) Four independent beta-glycerophosphates commonly act as two types of bidentate ligands, where one is the coordination to the calcium ion by the glycerol O(1) and phosphate O(22) atoms, and the other by the phosphate O(22) and O(23) atoms, thus forming the calcium coordination of a distorted square plane, respectively.
(13) For this purpose, bidentate ligands as hydroxamate and N-hydroxy-N-formylamino groups were selected as highly potent metal coordinating agents and introduced on Phe-Gly and Phe-Ala related structures.
(14) In order to investigate the function of Asp-327, a bidentate ligand of one of the zinc atoms in Escherichia coli alkaline phosphatase, and the importance of this zinc atom in catalysis, site-specific mutagenesis was used to convert Asp-327 to either asparagine or alanine.
(15) Bidentate or tridentate ligands on the other hand are able to attack the zinc ion directly; the rates are first order in enzyme and first order in ligand.
(16) All members of the new family contain a 1,3-dioxane or 1,3-dioxolane-1,3-diamine as their basic ligand, a moiety which contributes to their increased water solubility, and a bidentate acid ligand, which is responsible for their good stability.
(17) We sought evidence to determine whether contractions of the smooth muscle of the guinea pig vas deferens to ATP are in response to ATP4- or its bidentate complexes.
(18) It has been hypothesized that bidentate hydrogen bonding plays an important role in the interaction of imidazolylphenylformamidines with the H2-receptor.
(19) Deprotonated sulphonylurea act as bidentate ligands using one nitrogen and one oxygen atom (the ureido oxygen) to bind Zn2+ forming K[Zn(suphonylurea)3].
(20) An overall mechanism for inhibition by single and bidentate ligands is proposed.
Spear
Definition:
(n.) A long, pointed weapon, used in war and hunting, by thrusting or throwing; a weapon with a long shaft and a sharp head or blade; a lance.
(n.) Fig.: A spearman.
(n.) A sharp-pointed instrument with barbs, used for stabbing fish and other animals.
(n.) A shoot, as of grass; a spire.
(n.) The feather of a horse. See Feather, n., 4.
(n.) The rod to which the bucket, or plunger, of a pump is attached; a pump rod.
(v. t.) To pierce with a spear; to kill with a spear; as, to spear a fish.
(v. i.) To shoot into a long stem, as some plants. See Spire.
Example Sentences:
(1) The work, The Spear, by Brett Murray, unleashed a brouhaha that has hogged headlines for more than a week in South Africa and earned that inexhaustible accolade "painting-gate".
(2) To find out if any stone tips were being used on spears any earlier than that, Wilkins examined sharp stones found at a site called Kathu Pan, in the Northern Cape region of South Africa.
(3) If they refuse to do so, make the least show of resistance, or attempt to run away from you, you will fire upon and compell [sic] them to surrender, breaking and destroying the Spears, Clubs, and Waddies of all those you take prisoner.
(5) The spear-phishing tricks we saw the Chinese secret police using against the Dalai Lama in 2008 were being used by Russian crooks to steal money from US companies by 2010.
(6) The wealth magazine Spear’s noted, in an interview with a company that provides contract cleaners to the Dorchester, that a cleaner at the Park Lane hotel would have to work for 56 hours to be able to take an entry-level room for the night , before tax.
(7) Manipulation of intra abdominal embedded spears may require unusual surgical procedures, and no attempt to extract the weapon should be made before emergency laparotomy is carried out.
(8) López and Machado were defeated by Capriles in opposition primaries, but they rejected Capriles's willingness to enter into dialogue with Maduro on public safety following the murder in January of Mónica Spear, a former Miss Venezuela .
(9) Hemicellulose B and holocellulose from spear grass (Heteropogon contortus) were the best sources of carbon, and the optimum temperature was 27 degrees.
(10) Spears joked that she was “thrilled” at being added to the dating app.
(11) To evaluate these hypotheses, the nucleotide sequence of the mitochondrial cytochrome oxidase subunit II gene was determined from a bushbaby (Galago senegalensis), flying lemur (Cynocephalus variegatus), tree shrew (Tupaia glis), spear-nosed bat (Phyllostomus hastatus), rousette bat (Rousettus leschenaulti), and nine-banded armadillo (Dasypus novemcinctus) and was compared with published sequences of a human, cow, and mouse.
(12) Jesus' death was ensured by the thrust of a soldier's spear into his side.
(13) What an incredible contrast between the passionate compassion so emotively expressed in Britain and the ruthless bloodlust in Japan, where tens of thousands of dolphins are killed with spears on beaches every year and where crowds cheer the departure of a huge mechanised fleet whose objective is the mass slaughter of these majestic mammals in the Antarctic whale sanctuary.
(14) Spectra were obtained with synchrotron radiation from the SPEAR storage ring using highly sensitive fluorescence detectors.
(15) Twenty four hours of food and maternal deprivation, shown previously to increase brain serotonin and 5-hydroxyindole acetic acid and their ratio in neonates (L. P. Spear & F. M. Scalzo, 1984, Developmental Brain Research, in press) was observed to induce tail flick analgesia, an effect blocked by metergoline.
(16) Adult male hunters who used dogs and carried only one spear were injured most frequently.
(17) I try not to read my reviews, but there's always some friend who'll come along and, under the guise of trying to comfort you, let you know that you've been speared.
(18) This tusk specimen contains a metal spear with a wooden component, which is surrounded by a quiver-like osseous encasement.
(19) Facebook Twitter Pinterest Armed with a makeshift spear, an Assam man sets out to chase away the elephant that crushed a woman to death in the village of Galighat.
(20) By the 16th century the conduction of sound by a rod or the staff of a spear was reported by a number of writers; however, these writers considered these phenomena as a curiosity rather than having practical value.