(v. t.) To tie, or confine with a cord, band, ligature, chain, etc.; to fetter; to make fast; as, to bind grain in bundles; to bind a prisoner.
(v. t.) To confine, restrain, or hold by physical force or influence of any kind; as, attraction binds the planets to the sun; frost binds the earth, or the streams.
(v. t.) To cover, as with a bandage; to bandage or dress; -- sometimes with up; as, to bind up a wound.
(v. t.) To make fast ( a thing) about or upon something, as by tying; to encircle with something; as, to bind a belt about one; to bind a compress upon a part.
(v. t.) To prevent or restrain from customary or natural action; as, certain drugs bind the bowels.
(v. t.) To protect or strengthen by a band or binding, as the edge of a carpet or garment.
(v. t.) To sew or fasten together, and inclose in a cover; as, to bind a book.
(v. t.) Fig.: To oblige, restrain, or hold, by authority, law, duty, promise, vow, affection, or other moral tie; as, to bind the conscience; to bind by kindness; bound by affection; commerce binds nations to each other.
(v. t.) To bring (any one) under definite legal obligations; esp. under the obligation of a bond or covenant.
(v. t.) To place under legal obligation to serve; to indenture; as, to bind an apprentice; -- sometimes with out; as, bound out to service.
(v. i.) To tie; to confine by any ligature.
(v. i.) To contract; to grow hard or stiff; to cohere or stick together in a mass; as, clay binds by heat.
(v. i.) To be restrained from motion, or from customary or natural action, as by friction.
(v. i.) To exert a binding or restraining influence.
(n.) That which binds or ties.
(n.) Any twining or climbing plant or stem, esp. a hop vine; a bine.
(n.) Indurated clay, when much mixed with the oxide of iron.
(n.) A ligature or tie for grouping notes.
Example Sentences:
(1) Tryptic digestion of the membranes caused complete disappearance of the binding activity, but heat-treatment for 5 min at 70 degrees C caused only 40% loss of activity.
(2) Comparison of the S100 alpha-binding protein profiles in fast- and slow-twitch fibers of various species revealed few, if any, species- or fiber type-specific S100 binding proteins.
(3) Competition with the labelled 10B12 MAb for binding to the purified antigen was demonstrated in sera of tumor-bearing and immune rats.
(4) These studies led to the following conclusions: (a) all the prominent NHP which remain bound to DNA are also present in somewhat similar proportions in the saline-EDTA, Tris, and 0.35 M NaCl washes of nuclei; (b) a protein comigrating with actin is prominent in the first saline-EDTA wash of nuclei, but present as only a minor band in the subsequent washes and on washed chromatin; (c) the presence of nuclear matrix proteins in all the nuclear washes and cytosol indicates that these proteins are distributed throughout the cell; (d) a histone-binding protein (J2) analogous to the HMG1 protein of K. V. Shooter, G.H.
(5) Power urges the security council to "take the kind of credible, binding action warranted."
(6) The binding properties of formalin-fixed amelanotic melanoma cells were not identical to those of endothelial or unfixed target cells.
(7) Such an increase in antibody binding occurred simultaneously with an increase in the fluidity of surface lipid regions, as monitored by fluorescence depolarization of 1-(trimethylammoniophenyl)-6-phenyl-1,3,5-hexatriene.
(8) It has been generally believed that the ligand-binding of steroid hormone receptors triggers an allosteric change in receptor structure, manifested by an increased affinity of the receptor for DNA in vitro and nuclear target elements in vivo, as monitored by nuclear translocation.
(9) Lp(a) also complexes to plasmin-fibrinogen digests, and binding increases in proportion to the time of plasmin-induced fibrinogen degradation.
(10) Theoretical computations are performed of the intercalative binding of the neocarzinostatin chromophore (NCS) with the double-stranded oligonucleotides d(CGCG)2, d(GCGC)2, d(TATA)2 and d(ATAT)2.
(11) The LD50 of the following metal-binding chelating drugs, EDTA, diethylenetriaminepentaacetic acid (DTPA), hydroxyethylenediaminetriacetic acid (HEDTA), cyclohexanediaminotetraacetic acid (CDTA) and triethylenetetraminehexaacetic acid (TTHA) was evaluated in terms of mortality in rats after intraperitoneal administration and was found to be in the order: CDTA greater than EDTA greater than DTPA greater than TTHA greater than HEDTA.
(12) It was also able to inhibit the binding both of alpha-bungarotoxin and rabies virus glycoprotein to the acetylcholine receptor.
(13) We report a series of experiments designed to determine if agents and conditions that have been reported to alter sodium reabsorption, Na-K-ATPase activity or cellular structure in the rat distal nephron might also regulate the density or affinity of binding of 3H-metolazone to the putative thiazide receptor in the distal nephron.
(14) The procedure used in our laboratory was not able to provide accurate determination of the concentrations of these binding forms.
(15) The occupation of the high affinity calcium binding site by Ca(II) and Mn(II) does not influence the Cu(II) binding process, suggesting that there is no direct interaction between this site and the Cu(II) binding sites.
(16) PMN were found to be nonpermissive for HSV replication and were unable to bind virus in the absence of antibody.
(17) Radioligand binding studies revealed the presence of a single class of high-affinity (Kd = 2-6 X 10(-10) M) binding sites for ET-1 in both cells, although the maximal binding capacity of cardiac receptor was about 6- to 12-fold greater than that of vascular receptor.
(18) The transported pIgA was functional, as evidenced by its ability to bind to virus in an ELISA assay and to protect nonimmune mice against intranasal infection with H1N1 but not H3N2 influenza virus.
(19) The monoclonal antibody (mAb), SY38, binds to a cytoplasmic domain of synaptophysin.
(20) Binding data for both ligands to the enzyme yielded nonlinear Scatchard plots that analyze in terms of four negatively cooperative binding sites per enzyme tetramer.
Compromise
Definition:
(n.) A mutual agreement to refer matters in dispute to the decision of arbitrators.
(n.) A settlement by arbitration or by mutual consent reached by concession on both sides; a reciprocal abatement of extreme demands or rights, resulting in an agreement.
(n.) A committal to something derogatory or objectionable; a prejudicial concession; a surrender; as, a compromise of character or right.
(n.) To bind by mutual agreement; to agree.
(n.) To adjust and settle by mutual concessions; to compound.
(n.) To pledge by some act or declaration; to endanger the life, reputation, etc., of, by some act which can not be recalled; to expose to suspicion.
(v. i.) To agree; to accord.
(v. i.) To make concession for conciliation and peace.
Example Sentences:
(1) It is likely that trunk mobility is necessary to maintain integrity of SI joint and that absence of such mobility compromises SI joint structure in many paraplegics.
(2) These deficiencies in the data compromise HIV surveillance based on diagnostic testing, and supplementary bias-free data are needed.
(3) Steroids are not recommended because they may compromise defenses against an underlying disease process.
(4) The dose response effect in this tumor is steep and combinations which compromise the dose of adriamycin too greatly are showing inferior results.
(5) Furthermore, renal function in the elderly patient with CHF is markedly compromised.
(6) The compromised ice sheet tilts and he sinks into the Arctic Sea on the back of his faltering white Icelandic pony.
(7) The technique did not compromise cancer resection, excessively prolong operating time, or alter postoperative management.
(8) Patients treated with ciprofloxacin may need added coverage for anaerobes, but the drug's excellent activity against nosocomial pathogens and its availability in oral form allow for an early change to oral therapy without compromising effectiveness coupled with added savings and convenience.
(9) The blood flows of the kidneys, small intestine, liver, spleen and skin were less compromised in group ABC.
(10) This adverse treatment side effect has been implicated in the anorexia of cancer and can compromise the quality of patients' lives.
(11) The trust was a compromise hammered out in the wake of the Hutton report, when the corporation hoped to maintain the status quo by preserving the old BBC governors.
(12) "This crowd of charlatans ... look for one little thing they can say is wrong, and thus generalise that the science is entirely compromised."
(13) The 24% overall response rate suggests no compromise in activity on this schedule, with a significant reduction in toxicity.
(14) An equivalent maximum growth response of rats fed L-methionine or N-acetyl-L-methionine was obtained when the total dietary sulfur amino acids compromised 0.36-0.41% of the diet.
(15) Obama will meet with Binyamin Netanyahu and Mahmoud Abbas tomorrow as well, but US envoy George Mitchell has had no luck in recent weeks trying to persuade Netanyahu to compromise on the settlements.
(16) This approach was used in 42 shoulders with rotator cuff tears or posterior instability without complications of infection, failure of deltoid healing, or compromise of suprascapular or axillary nerves.
(17) If the Labour leader has his way, into the dustbin of history will go the "electoral college", the spatchcocked compromise that was a product of the Bennite wars of the 1980s.
(18) 2. beta-adrenoceptor blocking compounds, which are frequently used as first-line therapy in hypertension, may compromise blood flow to vital organs in view of the fact that they reduce cardiac output both acutely and during long-term treatment.
(19) In repeated reconciliation talks overseen by the UN, the ineffectual GNA has so far failed to reach a political compromise with its Tobruk-based rivals in the east, noticeably Haftar, head of the Libyan National Army.
(20) The spin-spin relaxation time T2 may be estimated using multiecho pulse sequences, but the accuracy of the estimate is dependent on the fidelity of the spin-echo amplitudes, which may be severely compromised by rf pulse and static field imperfections.