(v. t.) To tie, or confine with a cord, band, ligature, chain, etc.; to fetter; to make fast; as, to bind grain in bundles; to bind a prisoner.
(v. t.) To confine, restrain, or hold by physical force or influence of any kind; as, attraction binds the planets to the sun; frost binds the earth, or the streams.
(v. t.) To cover, as with a bandage; to bandage or dress; -- sometimes with up; as, to bind up a wound.
(v. t.) To make fast ( a thing) about or upon something, as by tying; to encircle with something; as, to bind a belt about one; to bind a compress upon a part.
(v. t.) To prevent or restrain from customary or natural action; as, certain drugs bind the bowels.
(v. t.) To protect or strengthen by a band or binding, as the edge of a carpet or garment.
(v. t.) To sew or fasten together, and inclose in a cover; as, to bind a book.
(v. t.) Fig.: To oblige, restrain, or hold, by authority, law, duty, promise, vow, affection, or other moral tie; as, to bind the conscience; to bind by kindness; bound by affection; commerce binds nations to each other.
(v. t.) To bring (any one) under definite legal obligations; esp. under the obligation of a bond or covenant.
(v. t.) To place under legal obligation to serve; to indenture; as, to bind an apprentice; -- sometimes with out; as, bound out to service.
(v. i.) To tie; to confine by any ligature.
(v. i.) To contract; to grow hard or stiff; to cohere or stick together in a mass; as, clay binds by heat.
(v. i.) To be restrained from motion, or from customary or natural action, as by friction.
(v. i.) To exert a binding or restraining influence.
(n.) That which binds or ties.
(n.) Any twining or climbing plant or stem, esp. a hop vine; a bine.
(n.) Indurated clay, when much mixed with the oxide of iron.
(n.) A ligature or tie for grouping notes.
Example Sentences:
(1) Tryptic digestion of the membranes caused complete disappearance of the binding activity, but heat-treatment for 5 min at 70 degrees C caused only 40% loss of activity.
(2) Comparison of the S100 alpha-binding protein profiles in fast- and slow-twitch fibers of various species revealed few, if any, species- or fiber type-specific S100 binding proteins.
(3) Competition with the labelled 10B12 MAb for binding to the purified antigen was demonstrated in sera of tumor-bearing and immune rats.
(4) These studies led to the following conclusions: (a) all the prominent NHP which remain bound to DNA are also present in somewhat similar proportions in the saline-EDTA, Tris, and 0.35 M NaCl washes of nuclei; (b) a protein comigrating with actin is prominent in the first saline-EDTA wash of nuclei, but present as only a minor band in the subsequent washes and on washed chromatin; (c) the presence of nuclear matrix proteins in all the nuclear washes and cytosol indicates that these proteins are distributed throughout the cell; (d) a histone-binding protein (J2) analogous to the HMG1 protein of K. V. Shooter, G.H.
(5) Power urges the security council to "take the kind of credible, binding action warranted."
(6) The binding properties of formalin-fixed amelanotic melanoma cells were not identical to those of endothelial or unfixed target cells.
(7) Such an increase in antibody binding occurred simultaneously with an increase in the fluidity of surface lipid regions, as monitored by fluorescence depolarization of 1-(trimethylammoniophenyl)-6-phenyl-1,3,5-hexatriene.
(8) It has been generally believed that the ligand-binding of steroid hormone receptors triggers an allosteric change in receptor structure, manifested by an increased affinity of the receptor for DNA in vitro and nuclear target elements in vivo, as monitored by nuclear translocation.
(9) Lp(a) also complexes to plasmin-fibrinogen digests, and binding increases in proportion to the time of plasmin-induced fibrinogen degradation.
(10) Theoretical computations are performed of the intercalative binding of the neocarzinostatin chromophore (NCS) with the double-stranded oligonucleotides d(CGCG)2, d(GCGC)2, d(TATA)2 and d(ATAT)2.
(11) The LD50 of the following metal-binding chelating drugs, EDTA, diethylenetriaminepentaacetic acid (DTPA), hydroxyethylenediaminetriacetic acid (HEDTA), cyclohexanediaminotetraacetic acid (CDTA) and triethylenetetraminehexaacetic acid (TTHA) was evaluated in terms of mortality in rats after intraperitoneal administration and was found to be in the order: CDTA greater than EDTA greater than DTPA greater than TTHA greater than HEDTA.
(12) It was also able to inhibit the binding both of alpha-bungarotoxin and rabies virus glycoprotein to the acetylcholine receptor.
(13) We report a series of experiments designed to determine if agents and conditions that have been reported to alter sodium reabsorption, Na-K-ATPase activity or cellular structure in the rat distal nephron might also regulate the density or affinity of binding of 3H-metolazone to the putative thiazide receptor in the distal nephron.
(14) The procedure used in our laboratory was not able to provide accurate determination of the concentrations of these binding forms.
(15) The occupation of the high affinity calcium binding site by Ca(II) and Mn(II) does not influence the Cu(II) binding process, suggesting that there is no direct interaction between this site and the Cu(II) binding sites.
(16) PMN were found to be nonpermissive for HSV replication and were unable to bind virus in the absence of antibody.
(17) Radioligand binding studies revealed the presence of a single class of high-affinity (Kd = 2-6 X 10(-10) M) binding sites for ET-1 in both cells, although the maximal binding capacity of cardiac receptor was about 6- to 12-fold greater than that of vascular receptor.
(18) The transported pIgA was functional, as evidenced by its ability to bind to virus in an ELISA assay and to protect nonimmune mice against intranasal infection with H1N1 but not H3N2 influenza virus.
(19) The monoclonal antibody (mAb), SY38, binds to a cytoplasmic domain of synaptophysin.
(20) Binding data for both ligands to the enzyme yielded nonlinear Scatchard plots that analyze in terms of four negatively cooperative binding sites per enzyme tetramer.
Couple
Definition:
(a.) That which joins or links two things together; a bond or tie; a coupler.
(a.) Two of the same kind connected or considered together; a pair; a brace.
(a.) A male and female associated together; esp., a man and woman who are married or betrothed.
(a.) See Couple-close.
(a.) One of the pairs of plates of two metals which compose a voltaic battery; -- called a voltaic couple or galvanic couple.
(a.) Two rotations, movements, etc., which are equal in amount but opposite in direction, and acting along parallel lines or around parallel axes.
(v.) To link or tie, as one thing to another; to connect or fasten together; to join.
(v.) To join in wedlock; to marry.
(v. i.) To come together as male and female; to copulate.
Example Sentences:
(1) Spermine clearly activated 45Ca uptake by coupled mitochondria, but had no effect on Ca2+ egress from mitochondria previously loaded with 45Ca.
(2) After transfection in CH4C1 cells the two isoforms are coupled with adenylate cyclase while only the shortest isoform appears negatively coupled to phospholipase C. Functional D2 dopamine receptors are present in human prolactinomas.
(3) Ferrocene derivatives, in general, show a degree of versatility, coupling the electron-transfer reactions of many enzymes.
(4) Since intracellular Ca2+ seems to play a role in stimulus-secretion coupling and ion movements, several aspects of Ca2+ homeostasis have been investigated in CF.
(5) Couples in need of help will be "encouraged" to come to a private agreement.
(6) To get a better understanding of the different cell interactions during the immune response to a hapten-carrier complex, the effects of immunogenic or tolerogenic injections of various hapten-containing compounds on the responses induced by immunization with the same hapten coupled to protein carriers were studied.
(7) Such a science puts men in a couple of scientific laws and suppresses the moment of active doing (accepting or refusing) as a sufficient preassumption of reality.
(8) In contrast, strains carrying the substitutions Ile-30----Phe, Gly-33----Leu, Gly-58----Leu, and Lys-34----Val and the Lys-34----Val, Glu-37----Gln double substitution were found to possess a coupled phenotype similar to that of the wild type.
(9) Couples applying to in vitro fertilization were admitted into this project when the sperm concentration was greater than 20 million per mL and motility greater than 30 per cent.
(10) Large emission intensity fluctuations are observed from analyte species in inductively coupled plasmas.
(11) At the weekend the couple’s daughter, Holly Graham, 29, expressed frustration at the lack of information coming from the Foreign Office and the tour operator that her parents travelled with.
(12) These results coupled with previous studies support activation of benz[j]aceanthrylene via both 2 and cyclopenta ring epoxidation.
(13) Homologous insemination in 52 couples during a period of one year yields a conception rate of 38.5%.
(14) Following the hypothesis that infertile patients may present emotional conflicts with regard to the wish of having a child, psychodynamic interviews were carried out with 116 infertile couples concomitantly with their first consultation at the Sterility Department.
(15) The objective of this work was to determine the efficacy of an endoscopic approach coupled to a Nd:YAG laser fiber in performing arytenoidectomy.
(16) During the couple's 30-year marriage she had twice reported him to the police for grabbing her by the throat, before they divorced in 2005.
(17) The rate of indole production is increased about 4-fold when the aminoacrylate produced is converted to S-(hydroxyethyl)-L-cysteine by a coupled beta-replacement reaction with beta-mercaptoethanol.
(18) Single injections never produced more than one coupled pair in P20 or older rats.
(19) The extensive conversion of anti-BPDE to B[a]PT-10-sulfonate under conditions where sulfite enhances diolepoxide mutagenicity, when coupled with this enhancement of diolepoxide mutagenicity by B[a]PT-10-sulfonate in the reverse mutation assay, supports this novel B[a]P derivative as a mediator of the sulfite-dependent enhancement of B[a]P genotoxicity.
(20) Bobbing in warming waters, this ancient ice fossil will be gone in a couple of weeks.