(v. t.) To tie, or confine with a cord, band, ligature, chain, etc.; to fetter; to make fast; as, to bind grain in bundles; to bind a prisoner.
(v. t.) To confine, restrain, or hold by physical force or influence of any kind; as, attraction binds the planets to the sun; frost binds the earth, or the streams.
(v. t.) To cover, as with a bandage; to bandage or dress; -- sometimes with up; as, to bind up a wound.
(v. t.) To make fast ( a thing) about or upon something, as by tying; to encircle with something; as, to bind a belt about one; to bind a compress upon a part.
(v. t.) To prevent or restrain from customary or natural action; as, certain drugs bind the bowels.
(v. t.) To protect or strengthen by a band or binding, as the edge of a carpet or garment.
(v. t.) To sew or fasten together, and inclose in a cover; as, to bind a book.
(v. t.) Fig.: To oblige, restrain, or hold, by authority, law, duty, promise, vow, affection, or other moral tie; as, to bind the conscience; to bind by kindness; bound by affection; commerce binds nations to each other.
(v. t.) To bring (any one) under definite legal obligations; esp. under the obligation of a bond or covenant.
(v. t.) To place under legal obligation to serve; to indenture; as, to bind an apprentice; -- sometimes with out; as, bound out to service.
(v. i.) To tie; to confine by any ligature.
(v. i.) To contract; to grow hard or stiff; to cohere or stick together in a mass; as, clay binds by heat.
(v. i.) To be restrained from motion, or from customary or natural action, as by friction.
(v. i.) To exert a binding or restraining influence.
(n.) That which binds or ties.
(n.) Any twining or climbing plant or stem, esp. a hop vine; a bine.
(n.) Indurated clay, when much mixed with the oxide of iron.
(n.) A ligature or tie for grouping notes.
Example Sentences:
(1) Tryptic digestion of the membranes caused complete disappearance of the binding activity, but heat-treatment for 5 min at 70 degrees C caused only 40% loss of activity.
(2) Comparison of the S100 alpha-binding protein profiles in fast- and slow-twitch fibers of various species revealed few, if any, species- or fiber type-specific S100 binding proteins.
(3) Competition with the labelled 10B12 MAb for binding to the purified antigen was demonstrated in sera of tumor-bearing and immune rats.
(4) These studies led to the following conclusions: (a) all the prominent NHP which remain bound to DNA are also present in somewhat similar proportions in the saline-EDTA, Tris, and 0.35 M NaCl washes of nuclei; (b) a protein comigrating with actin is prominent in the first saline-EDTA wash of nuclei, but present as only a minor band in the subsequent washes and on washed chromatin; (c) the presence of nuclear matrix proteins in all the nuclear washes and cytosol indicates that these proteins are distributed throughout the cell; (d) a histone-binding protein (J2) analogous to the HMG1 protein of K. V. Shooter, G.H.
(5) Power urges the security council to "take the kind of credible, binding action warranted."
(6) The binding properties of formalin-fixed amelanotic melanoma cells were not identical to those of endothelial or unfixed target cells.
(7) Such an increase in antibody binding occurred simultaneously with an increase in the fluidity of surface lipid regions, as monitored by fluorescence depolarization of 1-(trimethylammoniophenyl)-6-phenyl-1,3,5-hexatriene.
(8) It has been generally believed that the ligand-binding of steroid hormone receptors triggers an allosteric change in receptor structure, manifested by an increased affinity of the receptor for DNA in vitro and nuclear target elements in vivo, as monitored by nuclear translocation.
(9) Lp(a) also complexes to plasmin-fibrinogen digests, and binding increases in proportion to the time of plasmin-induced fibrinogen degradation.
(10) Theoretical computations are performed of the intercalative binding of the neocarzinostatin chromophore (NCS) with the double-stranded oligonucleotides d(CGCG)2, d(GCGC)2, d(TATA)2 and d(ATAT)2.
(11) The LD50 of the following metal-binding chelating drugs, EDTA, diethylenetriaminepentaacetic acid (DTPA), hydroxyethylenediaminetriacetic acid (HEDTA), cyclohexanediaminotetraacetic acid (CDTA) and triethylenetetraminehexaacetic acid (TTHA) was evaluated in terms of mortality in rats after intraperitoneal administration and was found to be in the order: CDTA greater than EDTA greater than DTPA greater than TTHA greater than HEDTA.
(12) It was also able to inhibit the binding both of alpha-bungarotoxin and rabies virus glycoprotein to the acetylcholine receptor.
(13) We report a series of experiments designed to determine if agents and conditions that have been reported to alter sodium reabsorption, Na-K-ATPase activity or cellular structure in the rat distal nephron might also regulate the density or affinity of binding of 3H-metolazone to the putative thiazide receptor in the distal nephron.
(14) The procedure used in our laboratory was not able to provide accurate determination of the concentrations of these binding forms.
(15) The occupation of the high affinity calcium binding site by Ca(II) and Mn(II) does not influence the Cu(II) binding process, suggesting that there is no direct interaction between this site and the Cu(II) binding sites.
(16) PMN were found to be nonpermissive for HSV replication and were unable to bind virus in the absence of antibody.
(17) Radioligand binding studies revealed the presence of a single class of high-affinity (Kd = 2-6 X 10(-10) M) binding sites for ET-1 in both cells, although the maximal binding capacity of cardiac receptor was about 6- to 12-fold greater than that of vascular receptor.
(18) The transported pIgA was functional, as evidenced by its ability to bind to virus in an ELISA assay and to protect nonimmune mice against intranasal infection with H1N1 but not H3N2 influenza virus.
(19) The monoclonal antibody (mAb), SY38, binds to a cytoplasmic domain of synaptophysin.
(20) Binding data for both ligands to the enzyme yielded nonlinear Scatchard plots that analyze in terms of four negatively cooperative binding sites per enzyme tetramer.
Crunch
Definition:
(v. i.) To chew with force and noise; to craunch.
(v. i.) To grind or press with violence and noise.
(v. i.) To emit a grinding or craunching noise.
(v. t.) To crush with the teeth; to chew with a grinding noise; to craunch; as, to crunch a biscuit.
Example Sentences:
(1) Recent data collected by the Games Outcomes Project and shared on the website Gamasutra backs up the view that crunch compounds these problems rather than solving them.
(2) Sometimes it can seem as if the history of the City is the history of its crises and disasters, from the banking crisis of 1825 (which saw undercapitalised banks collapse – perhaps the closest historic parallel to the contemporary credit crunch), through the Spanish panic of 1835, the railway bust of 1837, the crash of Overend Gurney, the Kaffir boom, the Westralian boom, the Marconi scandal, and so on and on – a theme with endless variations.
(3) Mitchell said enabling more big energy users to be paid for cutting demand at crunch times and building more interconnectors to other countries had worked better elsewhere.
(4) The fashion in Hollywood leading men now is for the sort of sculpted torso that requires months, if not years, of dedicated abdominal crunching.
(5) The market is lightly regulated and any problems could ripple out into a wider credit crunch.
(6) Recruitment has not returned to pre-credit crunch levels, and there is fierce competition for new jobs.
(7) The ratings agency also believes that a much-feared energy crunch which could take the lights out as soon as this winter or next will be temporary, with capacity margins rising to reach almost 20% by 2020.
(8) "I set out to create chips that used low-energy technology and that has allowed me to develop devices that can do all their data crunching on site.
(9) Total UK ad spend hit a previous high of £13.1bn in 2007 before dipping to £11.3bn in 2009 following the credit crunch and ensuing recession.
(10) The City is most focused on the investigation begun in April 2009 into the bank before it was rescued by the taxpayer following the takeover of ABN Amro, which left it crippled with bad debts and strapped for cash after paying too much for the bank just as the credit crunch began.
(11) In the year of the credit crunch, 2007, the bank's crucial tier one ratio – a measure of its financial health – was 4.7%.
(12) The munching, and some data crunching, produced firm statistical findings ("The flavour cowy was correlated with age and sourness, but was not correlated to any other flavours or tastes").
(13) As other countries look to transition to low-carbon alternatives with one eye on crunch climate talks in Paris later this year, Australia is pushing ahead with an expansion in coal extraction that its conservative prime minister Tony Abbott insists is “good for humanity”.
(14) Elisabeth Afseth, bond market expert at Evolution Securities, reckons that the first pointer of a fresh credit crunch was returning could be seen on August 18 this year when the European Central Bank revealed that one bank had borrowed $500m for a week – as it could not find the money on the open market.
(15) With the eurozone unravelling and world markets in turmoil, threatening even the meagre recovery the UK economy had achieved since the onset of the credit crunch, he repeatedly evokes a mood of national emergency to explain why the coalition he forged with David Cameron is the right government for the times.
(16) The atmospherics between the Athens government and its antagonists, which is now just about every player of importance in the rest of Europe, have been awful for weeks and have got more poisonous as they have neared the crunch.
(17) I used to get 8% on my savings before the credit crunch and was making money every month.
(18) The dramatic reconciliation of the warring factions comes as the credit crunch and worsening newspaper advertising market has left INM facing a funding crisis.
(19) Paragon's chief executive, Nigel Terrington, said the £200m facility from Macquarie would now be used to grant new loans and then as the facility was used up, the mortgages would be packaged up and sold off in the securitisation market that dried up in the credit crunch.
(20) But the world's largest insurer has seen its shares plunge in recent weeks as it reels from the effects of the credit crunch.