(v. t.) To tie, or confine with a cord, band, ligature, chain, etc.; to fetter; to make fast; as, to bind grain in bundles; to bind a prisoner.
(v. t.) To confine, restrain, or hold by physical force or influence of any kind; as, attraction binds the planets to the sun; frost binds the earth, or the streams.
(v. t.) To cover, as with a bandage; to bandage or dress; -- sometimes with up; as, to bind up a wound.
(v. t.) To make fast ( a thing) about or upon something, as by tying; to encircle with something; as, to bind a belt about one; to bind a compress upon a part.
(v. t.) To prevent or restrain from customary or natural action; as, certain drugs bind the bowels.
(v. t.) To protect or strengthen by a band or binding, as the edge of a carpet or garment.
(v. t.) To sew or fasten together, and inclose in a cover; as, to bind a book.
(v. t.) Fig.: To oblige, restrain, or hold, by authority, law, duty, promise, vow, affection, or other moral tie; as, to bind the conscience; to bind by kindness; bound by affection; commerce binds nations to each other.
(v. t.) To bring (any one) under definite legal obligations; esp. under the obligation of a bond or covenant.
(v. t.) To place under legal obligation to serve; to indenture; as, to bind an apprentice; -- sometimes with out; as, bound out to service.
(v. i.) To tie; to confine by any ligature.
(v. i.) To contract; to grow hard or stiff; to cohere or stick together in a mass; as, clay binds by heat.
(v. i.) To be restrained from motion, or from customary or natural action, as by friction.
(v. i.) To exert a binding or restraining influence.
(n.) That which binds or ties.
(n.) Any twining or climbing plant or stem, esp. a hop vine; a bine.
(n.) Indurated clay, when much mixed with the oxide of iron.
(n.) A ligature or tie for grouping notes.
Example Sentences:
(1) Tryptic digestion of the membranes caused complete disappearance of the binding activity, but heat-treatment for 5 min at 70 degrees C caused only 40% loss of activity.
(2) Comparison of the S100 alpha-binding protein profiles in fast- and slow-twitch fibers of various species revealed few, if any, species- or fiber type-specific S100 binding proteins.
(3) Competition with the labelled 10B12 MAb for binding to the purified antigen was demonstrated in sera of tumor-bearing and immune rats.
(4) These studies led to the following conclusions: (a) all the prominent NHP which remain bound to DNA are also present in somewhat similar proportions in the saline-EDTA, Tris, and 0.35 M NaCl washes of nuclei; (b) a protein comigrating with actin is prominent in the first saline-EDTA wash of nuclei, but present as only a minor band in the subsequent washes and on washed chromatin; (c) the presence of nuclear matrix proteins in all the nuclear washes and cytosol indicates that these proteins are distributed throughout the cell; (d) a histone-binding protein (J2) analogous to the HMG1 protein of K. V. Shooter, G.H.
(5) Power urges the security council to "take the kind of credible, binding action warranted."
(6) The binding properties of formalin-fixed amelanotic melanoma cells were not identical to those of endothelial or unfixed target cells.
(7) Such an increase in antibody binding occurred simultaneously with an increase in the fluidity of surface lipid regions, as monitored by fluorescence depolarization of 1-(trimethylammoniophenyl)-6-phenyl-1,3,5-hexatriene.
(8) It has been generally believed that the ligand-binding of steroid hormone receptors triggers an allosteric change in receptor structure, manifested by an increased affinity of the receptor for DNA in vitro and nuclear target elements in vivo, as monitored by nuclear translocation.
(9) Lp(a) also complexes to plasmin-fibrinogen digests, and binding increases in proportion to the time of plasmin-induced fibrinogen degradation.
(10) Theoretical computations are performed of the intercalative binding of the neocarzinostatin chromophore (NCS) with the double-stranded oligonucleotides d(CGCG)2, d(GCGC)2, d(TATA)2 and d(ATAT)2.
(11) The LD50 of the following metal-binding chelating drugs, EDTA, diethylenetriaminepentaacetic acid (DTPA), hydroxyethylenediaminetriacetic acid (HEDTA), cyclohexanediaminotetraacetic acid (CDTA) and triethylenetetraminehexaacetic acid (TTHA) was evaluated in terms of mortality in rats after intraperitoneal administration and was found to be in the order: CDTA greater than EDTA greater than DTPA greater than TTHA greater than HEDTA.
(12) It was also able to inhibit the binding both of alpha-bungarotoxin and rabies virus glycoprotein to the acetylcholine receptor.
(13) We report a series of experiments designed to determine if agents and conditions that have been reported to alter sodium reabsorption, Na-K-ATPase activity or cellular structure in the rat distal nephron might also regulate the density or affinity of binding of 3H-metolazone to the putative thiazide receptor in the distal nephron.
(14) The procedure used in our laboratory was not able to provide accurate determination of the concentrations of these binding forms.
(15) The occupation of the high affinity calcium binding site by Ca(II) and Mn(II) does not influence the Cu(II) binding process, suggesting that there is no direct interaction between this site and the Cu(II) binding sites.
(16) PMN were found to be nonpermissive for HSV replication and were unable to bind virus in the absence of antibody.
(17) Radioligand binding studies revealed the presence of a single class of high-affinity (Kd = 2-6 X 10(-10) M) binding sites for ET-1 in both cells, although the maximal binding capacity of cardiac receptor was about 6- to 12-fold greater than that of vascular receptor.
(18) The transported pIgA was functional, as evidenced by its ability to bind to virus in an ELISA assay and to protect nonimmune mice against intranasal infection with H1N1 but not H3N2 influenza virus.
(19) The monoclonal antibody (mAb), SY38, binds to a cytoplasmic domain of synaptophysin.
(20) Binding data for both ligands to the enzyme yielded nonlinear Scatchard plots that analyze in terms of four negatively cooperative binding sites per enzyme tetramer.
Dilemma
Definition:
(n.) An argument which presents an antagonist with two or more alternatives, but is equally conclusive against him, whichever alternative he chooses.
(n.) A state of things in which evils or obstacles present themselves on every side, and it is difficult to determine what course to pursue; a vexatious alternative or predicament; a difficult choice or position.
Example Sentences:
(1) The following case highlights the diagnostic and therapeutic dilemmas encountered in a middle-aged patient who presented with dementia and apathetic hyperthyroidism.
(2) The dilemmas faced by the genetic counsellor are discussed in this variable autosomal dominant condition.
(3) Dilemmas of trust, confidentiality, and professional competence highlight the limits of professional ethical codes.
(4) When faced with a big dilemma, the time-honoured tradition of politicians is to order an inquiry, and that is what Browne expects.
(5) This paper raises other issues for consideration, including problems associated with HIV testing, confidentiality, informed consent and the dilemmas facing those involved in the treatment of patients suffering from HIV infection.
(6) Various forms of inactive data storage and archiving in machine-readable form are available to address this dilemma, yet these solutions can create even more difficult problems.
(7) For Bush Sr, the dilemma is all the more agonising as some of the White House advisers he now criticises are former employees he bequeathed to his son.
(8) The patient with a cholesteatoma in an only hearing ear presents a management dilemma: how best to treat the patient to minimize the chances of developing a severe hearing loss in that ear.
(9) The dilemma focuses on whether the obliteration or removal of the cystic areas will benefit or cause further deterioration of the patient's condition.
(10) when a family is in conflict often creates a serious ethical dilemma for the family physician.
(11) Respondents did not deal with the simulated ethical problems in a uniform manner and often tended to respond more to specific details of a case rather than the overall ethical dilemma posed.
(12) This article examines AIDS- and HIV-related concerns in women with a focus on the personal dilemmas for the practicing psychologist, problems in health behavior advocacy, and methods and pitfalls in modifying sexual behaviors.
(13) Because many of these issues are unresolved, it is important for health professionals to be aware of current professional standards and guidelines, as well as to consult with the hospital's attorney or risk manager when confronted with a legal or ethical dilemma.
(14) These dilemmas were often "caused" by other group members (general practitioners or nurses), e.g., by not keeping appointment times or by not sharing information with patients.
(15) Solitary abnormalities on bone scan or chest film serve as an excellent examples of this dilemma.
(16) Corbyn’s ‘new politics’ is neither hateful nor pure: it’s complicated | John Harris Read more Their dilemma is plain: if they make a stand against what is happening, they stand accused of disloyalty by Corbyn’s supporters; but if they go along with it, they are complicit in Labour’s probable disintegration when voters realise the party has been taken over by people they can never vote for.
(17) Four cases of right lower quadrant abscess, each a clinical diagnostic dilemma, were recognized as abscesses surrounding a perforated viscus by application of the "coffee bean" sign on sonographic examination.
(18) This dilemma is aggravated by the loss from the work force of graduate nurses who fail the registered nurse licensure examination.
(19) Diagnosis of cecal diverticulitis remains a dilemma.
(20) This paper considers the dilemmas and tensions as reported, and on that basis certain policy issues are tabulated and presented.