(v. t.) To tie, or confine with a cord, band, ligature, chain, etc.; to fetter; to make fast; as, to bind grain in bundles; to bind a prisoner.
(v. t.) To confine, restrain, or hold by physical force or influence of any kind; as, attraction binds the planets to the sun; frost binds the earth, or the streams.
(v. t.) To cover, as with a bandage; to bandage or dress; -- sometimes with up; as, to bind up a wound.
(v. t.) To make fast ( a thing) about or upon something, as by tying; to encircle with something; as, to bind a belt about one; to bind a compress upon a part.
(v. t.) To prevent or restrain from customary or natural action; as, certain drugs bind the bowels.
(v. t.) To protect or strengthen by a band or binding, as the edge of a carpet or garment.
(v. t.) To sew or fasten together, and inclose in a cover; as, to bind a book.
(v. t.) Fig.: To oblige, restrain, or hold, by authority, law, duty, promise, vow, affection, or other moral tie; as, to bind the conscience; to bind by kindness; bound by affection; commerce binds nations to each other.
(v. t.) To bring (any one) under definite legal obligations; esp. under the obligation of a bond or covenant.
(v. t.) To place under legal obligation to serve; to indenture; as, to bind an apprentice; -- sometimes with out; as, bound out to service.
(v. i.) To tie; to confine by any ligature.
(v. i.) To contract; to grow hard or stiff; to cohere or stick together in a mass; as, clay binds by heat.
(v. i.) To be restrained from motion, or from customary or natural action, as by friction.
(v. i.) To exert a binding or restraining influence.
(n.) That which binds or ties.
(n.) Any twining or climbing plant or stem, esp. a hop vine; a bine.
(n.) Indurated clay, when much mixed with the oxide of iron.
(n.) A ligature or tie for grouping notes.
Example Sentences:
(1) Tryptic digestion of the membranes caused complete disappearance of the binding activity, but heat-treatment for 5 min at 70 degrees C caused only 40% loss of activity.
(2) Comparison of the S100 alpha-binding protein profiles in fast- and slow-twitch fibers of various species revealed few, if any, species- or fiber type-specific S100 binding proteins.
(3) Competition with the labelled 10B12 MAb for binding to the purified antigen was demonstrated in sera of tumor-bearing and immune rats.
(4) These studies led to the following conclusions: (a) all the prominent NHP which remain bound to DNA are also present in somewhat similar proportions in the saline-EDTA, Tris, and 0.35 M NaCl washes of nuclei; (b) a protein comigrating with actin is prominent in the first saline-EDTA wash of nuclei, but present as only a minor band in the subsequent washes and on washed chromatin; (c) the presence of nuclear matrix proteins in all the nuclear washes and cytosol indicates that these proteins are distributed throughout the cell; (d) a histone-binding protein (J2) analogous to the HMG1 protein of K. V. Shooter, G.H.
(5) Power urges the security council to "take the kind of credible, binding action warranted."
(6) The binding properties of formalin-fixed amelanotic melanoma cells were not identical to those of endothelial or unfixed target cells.
(7) Such an increase in antibody binding occurred simultaneously with an increase in the fluidity of surface lipid regions, as monitored by fluorescence depolarization of 1-(trimethylammoniophenyl)-6-phenyl-1,3,5-hexatriene.
(8) It has been generally believed that the ligand-binding of steroid hormone receptors triggers an allosteric change in receptor structure, manifested by an increased affinity of the receptor for DNA in vitro and nuclear target elements in vivo, as monitored by nuclear translocation.
(9) Lp(a) also complexes to plasmin-fibrinogen digests, and binding increases in proportion to the time of plasmin-induced fibrinogen degradation.
(10) Theoretical computations are performed of the intercalative binding of the neocarzinostatin chromophore (NCS) with the double-stranded oligonucleotides d(CGCG)2, d(GCGC)2, d(TATA)2 and d(ATAT)2.
(11) The LD50 of the following metal-binding chelating drugs, EDTA, diethylenetriaminepentaacetic acid (DTPA), hydroxyethylenediaminetriacetic acid (HEDTA), cyclohexanediaminotetraacetic acid (CDTA) and triethylenetetraminehexaacetic acid (TTHA) was evaluated in terms of mortality in rats after intraperitoneal administration and was found to be in the order: CDTA greater than EDTA greater than DTPA greater than TTHA greater than HEDTA.
(12) It was also able to inhibit the binding both of alpha-bungarotoxin and rabies virus glycoprotein to the acetylcholine receptor.
(13) We report a series of experiments designed to determine if agents and conditions that have been reported to alter sodium reabsorption, Na-K-ATPase activity or cellular structure in the rat distal nephron might also regulate the density or affinity of binding of 3H-metolazone to the putative thiazide receptor in the distal nephron.
(14) The procedure used in our laboratory was not able to provide accurate determination of the concentrations of these binding forms.
(15) The occupation of the high affinity calcium binding site by Ca(II) and Mn(II) does not influence the Cu(II) binding process, suggesting that there is no direct interaction between this site and the Cu(II) binding sites.
(16) PMN were found to be nonpermissive for HSV replication and were unable to bind virus in the absence of antibody.
(17) Radioligand binding studies revealed the presence of a single class of high-affinity (Kd = 2-6 X 10(-10) M) binding sites for ET-1 in both cells, although the maximal binding capacity of cardiac receptor was about 6- to 12-fold greater than that of vascular receptor.
(18) The transported pIgA was functional, as evidenced by its ability to bind to virus in an ELISA assay and to protect nonimmune mice against intranasal infection with H1N1 but not H3N2 influenza virus.
(19) The monoclonal antibody (mAb), SY38, binds to a cytoplasmic domain of synaptophysin.
(20) Binding data for both ligands to the enzyme yielded nonlinear Scatchard plots that analyze in terms of four negatively cooperative binding sites per enzyme tetramer.
Drop
Definition:
(n.) The quantity of fluid which falls in one small spherical mass; a liquid globule; a minim; hence, also, the smallest easily measured portion of a fluid; a small quantity; as, a drop of water.
(n.) That which resembles, or that which hangs like, a liquid drop; as a hanging diamond ornament, an earring, a glass pendant on a chandelier, a sugarplum (sometimes medicated), or a kind of shot or slug.
(n.) Same as Gutta.
(n.) Any small pendent ornament.
(n.) Whatever is arranged to drop, hang, or fall from an elevated position; also, a contrivance for lowering something
(n.) A door or platform opening downward; a trap door; that part of the gallows on which a culprit stands when he is to be hanged; hence, the gallows itself.
(n.) A machine for lowering heavy weights, as packages, coal wagons, etc., to a ship's deck.
(n.) A contrivance for temporarily lowering a gas jet.
(n.) A curtain which drops or falls in front of the stage of a theater, etc.
(n.) A drop press or drop hammer.
(n.) The distance of the axis of a shaft below the base of a hanger.
(n.) Any medicine the dose of which is measured by drops; as, lavender drops.
(n.) The depth of a square sail; -- generally applied to the courses only.
(n.) Act of dropping; sudden fall or descent.
(n.) To pour or let fall in drops; to pour in small globules; to distill.
(n.) To cause to fall in one portion, or by one motion, like a drop; to let fall; as, to drop a line in fishing; to drop a courtesy.
(n.) To let go; to dismiss; to set aside; to have done with; to discontinue; to forsake; to give up; to omit.
(n.) To bestow or communicate by a suggestion; to let fall in an indirect, cautious, or gentle manner; as, to drop hint, a word of counsel, etc.
(n.) To lower, as a curtain, or the muzzle of a gun, etc.
(n.) To send, as a letter; as, please drop me a line, a letter, word.
(n.) To give birth to; as, to drop a lamb.
(n.) To cover with drops; to variegate; to bedrop.
(v. i.) To fall in drops.
(v. i.) To fall, in general, literally or figuratively; as, ripe fruit drops from a tree; wise words drop from the lips.
(v. i.) To let drops fall; to discharge itself in drops.
(v. i.) To fall dead, or to fall in death.
(v. i.) To come to an end; to cease; to pass out of mind; as, the affair dropped.
(v. i.) To come unexpectedly; -- with in or into; as, my old friend dropped in a moment.
(v. i.) To fall or be depressed; to lower; as, the point of the spear dropped a little.
(v. i.) To fall short of a mark.
(v. i.) To be deep in extent; to descend perpendicularly; as, her main topsail drops seventeen yards.
Example Sentences:
(1) But soon after aid workers departed, barrel bombs dropped by Syrian helicopters caused renewed destruction.
(2) Systolic blood pressure dropped following clonidine, showing a significantly greater drop for the medium and high doses than for the low dose.
(3) In four main regions the conservation varied from 83-91% while in the remaining regions the homology dropped to between 56-62%.
(4) David Cameron last night hit out at his fellow world leaders after the G8 dropped the promise to meet the historic aid commitments made at Gleneagles in 2005 from this year's summit communique.
(5) "There is … a risk that the political, trade, and gas frictions with Russia could lead to strong deterioration in economic relations between the two countries, with a significant drop in Ukraine's exports to and imports from Russia.
(6) EI showed a tendency to drop from week 20 to week 40 in the men and a tendency to increase from week 20 to week 40 in the women.
(7) The percentage of eggs clamped at values more negative than -65 mV, which responded at insemination by developing an If, decreased and dropped to 0 at -80 mV.
(8) I hope they fight for the money to make their jobs worth doing, because it's only with the money (a drop in the ocean though it may be) that they'll be able to do anything.
(9) "Indeed, there was a marked drop in sentiment in Germany , indicating that it is increasingly being affected by the problems elsewhere in the eurozone."
(10) Of great influence on the results of measurements are preparation and registration (warm-up-time, amplification, closeness of pressure-system, unhurt catheters), factors relating to equipment and methods (air-bubbles in pressure-system, damping by filters, continuous infusion of the micro-catheter, level of zero-pressure), factors which occur during intravital measurement (pressure-drop along the arteria pulmonalis, influence of normal breathing, great intrapleural pressure changes, pressure damping in the catheter by thrombosis and external disturbances) and last not least positive and negative acceleration forces, which influence the diastolic and systolic pulmonary artery pressure.
(11) By vaccinating adult dogs in boarding kennels the morbidity rate dropped from 83.5% to 6.5% and the mortality rate from 4.1% to 0.5%.
(12) Subjects who trained an additional 52 wk showed a slight drop in SV at submaximal work loads from the initial increase following the first 9 wk.
(13) The drop in endosome pH increased and the shape of the distribution changed when the time between FITC-dextran infusion and kidney removal was increased from 5 to 20 min.
(14) Estimated fluid consumption dropped from 10 liters to 4 liters daily and incidents of hyponatremia decreased by 62%.
(15) Here's Dominic's full story: US unemployment rate drops to lowest level in six years as 288,000 jobs added Michael McKee (@mckonomy) BNP economists say jobless rate would have been 6.8% if not for drop in participation rate May 2, 2014 2.20pm BST ING's Rob Carnell is also struck by the "extraordinary weakness" of US wage growth .
(16) The Italian coastguard ship Bruno Gregoracci docked in Malta at about 8am and dropped off two dozen bodies recovered from this weekend’s wreck, including children, according to Save the Children.
(17) However, coinciding with the height of inflammation and clinical signs at 12 dpi, the GFAP mRNA content dropped to approximately 50% of the level at 11 dpi but rose again at 13 dpi.
(18) Mutai dropped back and Kebede proved too strong for Kirui, the world champion.
(19) The same dose of clonidine evoked a much larger drop in blood pressure in another group of rats in which an equialent increase in blood pressure was produced by bilateral section of the vagosympathetic trunks and occlusion of both carotid arteries.
(20) The risks are determined, mainly by expert committees, from the steadily growing information on exposed human populations, especially the survivors of the atomic bombs dropped in Japan in 1945.