(v. t.) To tie, or confine with a cord, band, ligature, chain, etc.; to fetter; to make fast; as, to bind grain in bundles; to bind a prisoner.
(v. t.) To confine, restrain, or hold by physical force or influence of any kind; as, attraction binds the planets to the sun; frost binds the earth, or the streams.
(v. t.) To cover, as with a bandage; to bandage or dress; -- sometimes with up; as, to bind up a wound.
(v. t.) To make fast ( a thing) about or upon something, as by tying; to encircle with something; as, to bind a belt about one; to bind a compress upon a part.
(v. t.) To prevent or restrain from customary or natural action; as, certain drugs bind the bowels.
(v. t.) To protect or strengthen by a band or binding, as the edge of a carpet or garment.
(v. t.) To sew or fasten together, and inclose in a cover; as, to bind a book.
(v. t.) Fig.: To oblige, restrain, or hold, by authority, law, duty, promise, vow, affection, or other moral tie; as, to bind the conscience; to bind by kindness; bound by affection; commerce binds nations to each other.
(v. t.) To bring (any one) under definite legal obligations; esp. under the obligation of a bond or covenant.
(v. t.) To place under legal obligation to serve; to indenture; as, to bind an apprentice; -- sometimes with out; as, bound out to service.
(v. i.) To tie; to confine by any ligature.
(v. i.) To contract; to grow hard or stiff; to cohere or stick together in a mass; as, clay binds by heat.
(v. i.) To be restrained from motion, or from customary or natural action, as by friction.
(v. i.) To exert a binding or restraining influence.
(n.) That which binds or ties.
(n.) Any twining or climbing plant or stem, esp. a hop vine; a bine.
(n.) Indurated clay, when much mixed with the oxide of iron.
(n.) A ligature or tie for grouping notes.
Example Sentences:
(1) Tryptic digestion of the membranes caused complete disappearance of the binding activity, but heat-treatment for 5 min at 70 degrees C caused only 40% loss of activity.
(2) Comparison of the S100 alpha-binding protein profiles in fast- and slow-twitch fibers of various species revealed few, if any, species- or fiber type-specific S100 binding proteins.
(3) Competition with the labelled 10B12 MAb for binding to the purified antigen was demonstrated in sera of tumor-bearing and immune rats.
(4) These studies led to the following conclusions: (a) all the prominent NHP which remain bound to DNA are also present in somewhat similar proportions in the saline-EDTA, Tris, and 0.35 M NaCl washes of nuclei; (b) a protein comigrating with actin is prominent in the first saline-EDTA wash of nuclei, but present as only a minor band in the subsequent washes and on washed chromatin; (c) the presence of nuclear matrix proteins in all the nuclear washes and cytosol indicates that these proteins are distributed throughout the cell; (d) a histone-binding protein (J2) analogous to the HMG1 protein of K. V. Shooter, G.H.
(5) Power urges the security council to "take the kind of credible, binding action warranted."
(6) The binding properties of formalin-fixed amelanotic melanoma cells were not identical to those of endothelial or unfixed target cells.
(7) Such an increase in antibody binding occurred simultaneously with an increase in the fluidity of surface lipid regions, as monitored by fluorescence depolarization of 1-(trimethylammoniophenyl)-6-phenyl-1,3,5-hexatriene.
(8) It has been generally believed that the ligand-binding of steroid hormone receptors triggers an allosteric change in receptor structure, manifested by an increased affinity of the receptor for DNA in vitro and nuclear target elements in vivo, as monitored by nuclear translocation.
(9) Lp(a) also complexes to plasmin-fibrinogen digests, and binding increases in proportion to the time of plasmin-induced fibrinogen degradation.
(10) Theoretical computations are performed of the intercalative binding of the neocarzinostatin chromophore (NCS) with the double-stranded oligonucleotides d(CGCG)2, d(GCGC)2, d(TATA)2 and d(ATAT)2.
(11) The LD50 of the following metal-binding chelating drugs, EDTA, diethylenetriaminepentaacetic acid (DTPA), hydroxyethylenediaminetriacetic acid (HEDTA), cyclohexanediaminotetraacetic acid (CDTA) and triethylenetetraminehexaacetic acid (TTHA) was evaluated in terms of mortality in rats after intraperitoneal administration and was found to be in the order: CDTA greater than EDTA greater than DTPA greater than TTHA greater than HEDTA.
(12) It was also able to inhibit the binding both of alpha-bungarotoxin and rabies virus glycoprotein to the acetylcholine receptor.
(13) We report a series of experiments designed to determine if agents and conditions that have been reported to alter sodium reabsorption, Na-K-ATPase activity or cellular structure in the rat distal nephron might also regulate the density or affinity of binding of 3H-metolazone to the putative thiazide receptor in the distal nephron.
(14) The procedure used in our laboratory was not able to provide accurate determination of the concentrations of these binding forms.
(15) The occupation of the high affinity calcium binding site by Ca(II) and Mn(II) does not influence the Cu(II) binding process, suggesting that there is no direct interaction between this site and the Cu(II) binding sites.
(16) PMN were found to be nonpermissive for HSV replication and were unable to bind virus in the absence of antibody.
(17) Radioligand binding studies revealed the presence of a single class of high-affinity (Kd = 2-6 X 10(-10) M) binding sites for ET-1 in both cells, although the maximal binding capacity of cardiac receptor was about 6- to 12-fold greater than that of vascular receptor.
(18) The transported pIgA was functional, as evidenced by its ability to bind to virus in an ELISA assay and to protect nonimmune mice against intranasal infection with H1N1 but not H3N2 influenza virus.
(19) The monoclonal antibody (mAb), SY38, binds to a cytoplasmic domain of synaptophysin.
(20) Binding data for both ligands to the enzyme yielded nonlinear Scatchard plots that analyze in terms of four negatively cooperative binding sites per enzyme tetramer.
Engage
Definition:
(v. t.) To put under pledge; to pledge; to place under obligations to do or forbear doing something, as by a pledge, oath, or promise; to bind by contract or promise.
(v. t.) To gain for service; to bring in as associate or aid; to enlist; as, to engage friends to aid in a cause; to engage men for service.
(v. t.) To gain over; to win and attach; to attract and hold; to draw.
(v. t.) To employ the attention and efforts of; to occupy; to engross; to draw on.
(v. t.) To enter into contest with; to encounter; to bring to conflict.
(v. t.) To come into gear with; as, the teeth of one cogwheel engage those of another, or one part of a clutch engages the other part.
(v. i.) To promise or pledge one's self; to enter into an obligation; to become bound; to warrant.
(v. i.) To embark in a business; to take a part; to employ or involve one's self; to devote attention and effort; to enlist; as, to engage in controversy.
(v. i.) To enter into conflict; to join battle; as, the armies engaged in a general battle.
(v. i.) To be in gear, as two cogwheels working together.
Example Sentences:
(1) This finding is of major importance for persons treated with diltiazem who engage in sport.
(2) "But we develop a picture of someone from their previous engagements with us.
(3) In this study we were engaged on the pharmacokinetics of fosfestrol (Honvan) after oral administration.
(4) It is also a clear sign of our willingness and determination to step up engagement across the whole range of the EU-Turkey relationship to fully reflect the strategic importance of our relations.
(5) Nice (the National Institute for Health and Clinical Excellence) has also published new guidance on good patient experience that provides a strong framework on which to build good engagement practice.
(6) A man wearing a badge that says "property team" quietly parries some of her points, but chooses not to engage with others.
(7) I never had any doubt that the vast majority of people engaged in "business" are not the exploiters but the exploited.
(8) The need here is to promote the development of genuinely participative models – citizens panels and juries, patient and community leaders, participatory budgeting, and harnessing the power of digital engagement.
(9) Engagement in reminiscing may be stable during old age or may follow a developmental course.
(10) Using allozymes as the genetic probe, data are presented which show that wild Drosophila buzzatii females and males engaged in copulation mate at random.
(11) "This will obviously be a sensitive topic for the US administration, but partners in the transatlantic alliance must be clear on common rules of engagement in times of conflict if we are to retain any moral standing in the world," Verhofstadt said.
(12) Enright said: “We call on the home secretary and chair of IICSA [the independent inquiry into child sexual abuse] to engage actively and urgently to find a way forward that secures the confidence of survivors and provides the inquiry’s legal team with the resources and support they need to deliver justice and truth that survivors deserve.” Stein said his clients were “deeply disatisfied” with aspects of how the inquiry had been conducted but called for Emmerson to stay, adding: “I urge the home secretary to seek to find a way in which his valuable contribution can be maintained”.
(13) However, the mean serum EPO concentrations of male and female athletes engaged in a variety of sports were not different from those of sedentary control subjects of both sexes (26.5-35.3 U.ml-1).
(14) The findings may have a more general significance in relation to the site of engagement between processed antigen and MHC molecules in specialized antigen-presenting cells.
(15) These steps signify a willingness for engagement not seen before, but they have been overshadowed by the "nuclear crisis" triggered in October 2002 when Pyongyang admitted to having the "know-how", but not the technology, for a highly enriched uranium route to nuclear weapons.
(16) Through cues or precues, attention was directed to one location of a multistimulus visual display and, while attention was so engaged, the identity of a stimulus located at a different position in the display was changed.
(17) An Ofsted for universities Read more Too often a commitment to learning and teaching is presented in opposition to engagement with research and scholarship, but the two should be inextricably linked.
(18) And he failed to engage with these sensible proposals to limit bonuses to a maximum of a year's salary or double that if explicitly backed by shareholders - proposals which even his own MEPs have backed – until the very last minute.
(19) And an increasing number of critics say that no nuclear weapon would be a credible deterrent in any counter-terrorist operation British forces will be engaged in for the foreseeable future.
(20) The patient was engaged in the magistraliter preparations of medicaments in a pharmacy.