(v. t.) To tie, or confine with a cord, band, ligature, chain, etc.; to fetter; to make fast; as, to bind grain in bundles; to bind a prisoner.
(v. t.) To confine, restrain, or hold by physical force or influence of any kind; as, attraction binds the planets to the sun; frost binds the earth, or the streams.
(v. t.) To cover, as with a bandage; to bandage or dress; -- sometimes with up; as, to bind up a wound.
(v. t.) To make fast ( a thing) about or upon something, as by tying; to encircle with something; as, to bind a belt about one; to bind a compress upon a part.
(v. t.) To prevent or restrain from customary or natural action; as, certain drugs bind the bowels.
(v. t.) To protect or strengthen by a band or binding, as the edge of a carpet or garment.
(v. t.) To sew or fasten together, and inclose in a cover; as, to bind a book.
(v. t.) Fig.: To oblige, restrain, or hold, by authority, law, duty, promise, vow, affection, or other moral tie; as, to bind the conscience; to bind by kindness; bound by affection; commerce binds nations to each other.
(v. t.) To bring (any one) under definite legal obligations; esp. under the obligation of a bond or covenant.
(v. t.) To place under legal obligation to serve; to indenture; as, to bind an apprentice; -- sometimes with out; as, bound out to service.
(v. i.) To tie; to confine by any ligature.
(v. i.) To contract; to grow hard or stiff; to cohere or stick together in a mass; as, clay binds by heat.
(v. i.) To be restrained from motion, or from customary or natural action, as by friction.
(v. i.) To exert a binding or restraining influence.
(n.) That which binds or ties.
(n.) Any twining or climbing plant or stem, esp. a hop vine; a bine.
(n.) Indurated clay, when much mixed with the oxide of iron.
(n.) A ligature or tie for grouping notes.
Example Sentences:
(1) Tryptic digestion of the membranes caused complete disappearance of the binding activity, but heat-treatment for 5 min at 70 degrees C caused only 40% loss of activity.
(2) Comparison of the S100 alpha-binding protein profiles in fast- and slow-twitch fibers of various species revealed few, if any, species- or fiber type-specific S100 binding proteins.
(3) Competition with the labelled 10B12 MAb for binding to the purified antigen was demonstrated in sera of tumor-bearing and immune rats.
(4) These studies led to the following conclusions: (a) all the prominent NHP which remain bound to DNA are also present in somewhat similar proportions in the saline-EDTA, Tris, and 0.35 M NaCl washes of nuclei; (b) a protein comigrating with actin is prominent in the first saline-EDTA wash of nuclei, but present as only a minor band in the subsequent washes and on washed chromatin; (c) the presence of nuclear matrix proteins in all the nuclear washes and cytosol indicates that these proteins are distributed throughout the cell; (d) a histone-binding protein (J2) analogous to the HMG1 protein of K. V. Shooter, G.H.
(5) Power urges the security council to "take the kind of credible, binding action warranted."
(6) The binding properties of formalin-fixed amelanotic melanoma cells were not identical to those of endothelial or unfixed target cells.
(7) Such an increase in antibody binding occurred simultaneously with an increase in the fluidity of surface lipid regions, as monitored by fluorescence depolarization of 1-(trimethylammoniophenyl)-6-phenyl-1,3,5-hexatriene.
(8) It has been generally believed that the ligand-binding of steroid hormone receptors triggers an allosteric change in receptor structure, manifested by an increased affinity of the receptor for DNA in vitro and nuclear target elements in vivo, as monitored by nuclear translocation.
(9) Lp(a) also complexes to plasmin-fibrinogen digests, and binding increases in proportion to the time of plasmin-induced fibrinogen degradation.
(10) Theoretical computations are performed of the intercalative binding of the neocarzinostatin chromophore (NCS) with the double-stranded oligonucleotides d(CGCG)2, d(GCGC)2, d(TATA)2 and d(ATAT)2.
(11) The LD50 of the following metal-binding chelating drugs, EDTA, diethylenetriaminepentaacetic acid (DTPA), hydroxyethylenediaminetriacetic acid (HEDTA), cyclohexanediaminotetraacetic acid (CDTA) and triethylenetetraminehexaacetic acid (TTHA) was evaluated in terms of mortality in rats after intraperitoneal administration and was found to be in the order: CDTA greater than EDTA greater than DTPA greater than TTHA greater than HEDTA.
(12) It was also able to inhibit the binding both of alpha-bungarotoxin and rabies virus glycoprotein to the acetylcholine receptor.
(13) We report a series of experiments designed to determine if agents and conditions that have been reported to alter sodium reabsorption, Na-K-ATPase activity or cellular structure in the rat distal nephron might also regulate the density or affinity of binding of 3H-metolazone to the putative thiazide receptor in the distal nephron.
(14) The procedure used in our laboratory was not able to provide accurate determination of the concentrations of these binding forms.
(15) The occupation of the high affinity calcium binding site by Ca(II) and Mn(II) does not influence the Cu(II) binding process, suggesting that there is no direct interaction between this site and the Cu(II) binding sites.
(16) PMN were found to be nonpermissive for HSV replication and were unable to bind virus in the absence of antibody.
(17) Radioligand binding studies revealed the presence of a single class of high-affinity (Kd = 2-6 X 10(-10) M) binding sites for ET-1 in both cells, although the maximal binding capacity of cardiac receptor was about 6- to 12-fold greater than that of vascular receptor.
(18) The transported pIgA was functional, as evidenced by its ability to bind to virus in an ELISA assay and to protect nonimmune mice against intranasal infection with H1N1 but not H3N2 influenza virus.
(19) The monoclonal antibody (mAb), SY38, binds to a cytoplasmic domain of synaptophysin.
(20) Binding data for both ligands to the enzyme yielded nonlinear Scatchard plots that analyze in terms of four negatively cooperative binding sites per enzyme tetramer.
Knot
Definition:
(n.) A figure the lines of which are interlaced or intricately interwoven, as in embroidery, gardening, etc.
(n.) A fastening together of the pars or ends of one or more threads, cords, ropes, etc., by any one of various ways of tying or entangling.
(n.) A lump or loop formed in a thread, cord, rope. etc., as at the end, by tying or interweaving it upon itself.
(n.) An ornamental tie, as of a ribbon.
(n.) A bond of union; a connection; a tie.
(n.) Something not easily solved; an intricacy; a difficulty; a perplexity; a problem.
(n.) A cluster of persons or things; a collection; a group; a hand; a clique; as, a knot of politicians.
(n.) A portion of a branch of a tree that forms a mass of woody fiber running at an angle with the grain of the main stock and making a hard place in the timber. A loose knot is generally the remains of a dead branch of a tree covered by later woody growth.
(n.) A knob, lump, swelling, or protuberance.
(n.) A protuberant joint in a plant.
(n.) The point on which the action of a story depends; the gist of a matter.
(n.) See Node.
(n.) A division of the log line, serving to measure the rate of the vessel's motion. Each knot on the line bears the same proportion to a mile that thirty seconds do to an hour. The number of knots which run off from the reel in half a minute, therefore, shows the number of miles the vessel sails in an hour.
(n.) A nautical mile, or 6080.27 feet; as, when a ship goes eight miles an hour, her speed is said to be eight knots.
(n.) A kind of epaulet. See Shoulder knot.
(n.) A sandpiper (Tringa canutus), found in the northern parts of all the continents, in summer. It is grayish or ashy above, with the rump and upper tail coverts white, barred with dusky. The lower parts are pale brown, with the flanks and under tail coverts white. When fat it is prized by epicures. Called also dunne.
(v. t.) To tie in or with, or form into, a knot or knots; to form a knot on, as a rope; to entangle.
(v. t.) To unite closely; to knit together.
(v. t.) To entangle or perplex; to puzzle.
(v. i.) To form knots or joints, as in a cord, a plant, etc.; to become entangled.
(v. i.) To knit knots for fringe or trimming.
(v. i.) To copulate; -- said of toads.
Example Sentences:
(1) Two years ago I met a wonderful man and we now feel it’s time to tie the knot.
(2) The tinsel coiled around a jug of squash and bauble in the strip lighting made a golf-ball size knot of guilt burn in my throat.
(3) It is emphasized that surgeons should be more aware of the relationship of the holding power of surgical knots to not only the knot-typing technique but also the kind of suture material used.
(4) When a supercoiled substrate bearing two FLP target sequences in inverse orientation is treated with FLP, the products are multiply knotted structures that arise as a result of random entrapment of interdomainal supercoils.
(5) In principle, the more turns and throws the stronger the knot.
(6) Also numerous small knots on the small intestine, peritoneum, and omentum, as well as a considerable amount of ascites were observed.
(7) Suture knots are buried in the sclera to minimize the risk of late-onset endophthalmitis.
(8) The catheter with intact triple knots could be withdrawn without an invasive maneuver.
(9) A more detailed analysis of the products from recombination between wild-type sites indicates: (1) that the catenanes or knots produced by recombination are both simple and complex; (2) that the ratio of free products to catenanes is independent of the distance between the two directly repeated loxP sites; and (3) that for DNA substrates with four loxP sites significant recombination between non-adjacent sites occurs to give free circular products.
(10) This article studies the different knots, modalities and sutures.
(11) The mechanical performance of these sutures was judged by the following parameters: knot breakage force, configuration of secure knots, and knot run down force.
(12) This could be of important use in expediting root-knot nematode resistance (based on the Aps 1-linked resistance gene Mi) screening for breeding programs, or F1 testing for seed production purposes.
(13) After this manoeuvre, both the introducer and the small knot could be withdrawn from the jugular vein without further incident.
(14) The former appears characteristic of circularly bent DNA and gives rise to a substantial retardation, the latter of bending across a knot or kink in the DNA chain associated with a relatively minor retardation relative to standards.
(15) The suture appears to be solid, and the knots do not loosen.
(16) Now before you get your knickers in a knot, of course I love my children – and I do a decent job of caring for them.
(17) With respect to handling, knotting, tissue drag, absorption, and postoperative complications, the improved Dexon suture was found to be well suited for use in cataract surgery.
(18) The reduced phacoemulsification incision size in combination with a scleral pocket closed with a continuous single knotted 10-0 monofilament nylon suture under tonometric and keratometric control significantly dampens the changes in corneal astigmatism during the early and late postoperative periods.
(19) Two new triterpenoid saponins, wistariasaponins D [1] amd G [2], and the known saponin dehydrosoyasaponin I [3] were isolated from the knots of Wistaria brachybotrys.
(20) Loose ends in efforts to untangle the Gordian knot of Syria | Letters Read more “What is important is Russia has to not be engaged in any activities against anybody but [Isis],” secretary of state John Kerry said.