(v. t.) To tie, or confine with a cord, band, ligature, chain, etc.; to fetter; to make fast; as, to bind grain in bundles; to bind a prisoner.
(v. t.) To confine, restrain, or hold by physical force or influence of any kind; as, attraction binds the planets to the sun; frost binds the earth, or the streams.
(v. t.) To cover, as with a bandage; to bandage or dress; -- sometimes with up; as, to bind up a wound.
(v. t.) To make fast ( a thing) about or upon something, as by tying; to encircle with something; as, to bind a belt about one; to bind a compress upon a part.
(v. t.) To prevent or restrain from customary or natural action; as, certain drugs bind the bowels.
(v. t.) To protect or strengthen by a band or binding, as the edge of a carpet or garment.
(v. t.) To sew or fasten together, and inclose in a cover; as, to bind a book.
(v. t.) Fig.: To oblige, restrain, or hold, by authority, law, duty, promise, vow, affection, or other moral tie; as, to bind the conscience; to bind by kindness; bound by affection; commerce binds nations to each other.
(v. t.) To bring (any one) under definite legal obligations; esp. under the obligation of a bond or covenant.
(v. t.) To place under legal obligation to serve; to indenture; as, to bind an apprentice; -- sometimes with out; as, bound out to service.
(v. i.) To tie; to confine by any ligature.
(v. i.) To contract; to grow hard or stiff; to cohere or stick together in a mass; as, clay binds by heat.
(v. i.) To be restrained from motion, or from customary or natural action, as by friction.
(v. i.) To exert a binding or restraining influence.
(n.) That which binds or ties.
(n.) Any twining or climbing plant or stem, esp. a hop vine; a bine.
(n.) Indurated clay, when much mixed with the oxide of iron.
(n.) A ligature or tie for grouping notes.
Example Sentences:
(1) Tryptic digestion of the membranes caused complete disappearance of the binding activity, but heat-treatment for 5 min at 70 degrees C caused only 40% loss of activity.
(2) Comparison of the S100 alpha-binding protein profiles in fast- and slow-twitch fibers of various species revealed few, if any, species- or fiber type-specific S100 binding proteins.
(3) Competition with the labelled 10B12 MAb for binding to the purified antigen was demonstrated in sera of tumor-bearing and immune rats.
(4) These studies led to the following conclusions: (a) all the prominent NHP which remain bound to DNA are also present in somewhat similar proportions in the saline-EDTA, Tris, and 0.35 M NaCl washes of nuclei; (b) a protein comigrating with actin is prominent in the first saline-EDTA wash of nuclei, but present as only a minor band in the subsequent washes and on washed chromatin; (c) the presence of nuclear matrix proteins in all the nuclear washes and cytosol indicates that these proteins are distributed throughout the cell; (d) a histone-binding protein (J2) analogous to the HMG1 protein of K. V. Shooter, G.H.
(5) Power urges the security council to "take the kind of credible, binding action warranted."
(6) The binding properties of formalin-fixed amelanotic melanoma cells were not identical to those of endothelial or unfixed target cells.
(7) Such an increase in antibody binding occurred simultaneously with an increase in the fluidity of surface lipid regions, as monitored by fluorescence depolarization of 1-(trimethylammoniophenyl)-6-phenyl-1,3,5-hexatriene.
(8) It has been generally believed that the ligand-binding of steroid hormone receptors triggers an allosteric change in receptor structure, manifested by an increased affinity of the receptor for DNA in vitro and nuclear target elements in vivo, as monitored by nuclear translocation.
(9) Lp(a) also complexes to plasmin-fibrinogen digests, and binding increases in proportion to the time of plasmin-induced fibrinogen degradation.
(10) Theoretical computations are performed of the intercalative binding of the neocarzinostatin chromophore (NCS) with the double-stranded oligonucleotides d(CGCG)2, d(GCGC)2, d(TATA)2 and d(ATAT)2.
(11) The LD50 of the following metal-binding chelating drugs, EDTA, diethylenetriaminepentaacetic acid (DTPA), hydroxyethylenediaminetriacetic acid (HEDTA), cyclohexanediaminotetraacetic acid (CDTA) and triethylenetetraminehexaacetic acid (TTHA) was evaluated in terms of mortality in rats after intraperitoneal administration and was found to be in the order: CDTA greater than EDTA greater than DTPA greater than TTHA greater than HEDTA.
(12) It was also able to inhibit the binding both of alpha-bungarotoxin and rabies virus glycoprotein to the acetylcholine receptor.
(13) We report a series of experiments designed to determine if agents and conditions that have been reported to alter sodium reabsorption, Na-K-ATPase activity or cellular structure in the rat distal nephron might also regulate the density or affinity of binding of 3H-metolazone to the putative thiazide receptor in the distal nephron.
(14) The procedure used in our laboratory was not able to provide accurate determination of the concentrations of these binding forms.
(15) The occupation of the high affinity calcium binding site by Ca(II) and Mn(II) does not influence the Cu(II) binding process, suggesting that there is no direct interaction between this site and the Cu(II) binding sites.
(16) PMN were found to be nonpermissive for HSV replication and were unable to bind virus in the absence of antibody.
(17) Radioligand binding studies revealed the presence of a single class of high-affinity (Kd = 2-6 X 10(-10) M) binding sites for ET-1 in both cells, although the maximal binding capacity of cardiac receptor was about 6- to 12-fold greater than that of vascular receptor.
(18) The transported pIgA was functional, as evidenced by its ability to bind to virus in an ELISA assay and to protect nonimmune mice against intranasal infection with H1N1 but not H3N2 influenza virus.
(19) The monoclonal antibody (mAb), SY38, binds to a cytoplasmic domain of synaptophysin.
(20) Binding data for both ligands to the enzyme yielded nonlinear Scatchard plots that analyze in terms of four negatively cooperative binding sites per enzyme tetramer.
Predicament
Definition:
(n.) A class or kind described by any definite marks; hence, condition; particular situation or state; especially, an unfortunate or trying position or condition.
(n.) See Category.
Example Sentences:
(1) I can’t stay here anymore.” When his mother calls, he says, he refuses to talk to her, blaming her in part for his predicament.
(2) I had told Chris that I would need an electric hook-up and told him about my predicament.
(3) As one example, certain aspects of Gawain's situation seem oddly redolent of a more contemporary predicament, namely our complex and delicate relationship with the natural world.
(4) How are medical roles adapted to the situation of medical pluralism and the predicaments that flow from such a situation.
(5) High tension and high stakes coursed through this meeting of top four chasers versus relegation facers and it was to QPR’s credit that they attacked their predicament – and Arsenal – head on.
(6) Clinical research and opinion in this area have elicited both clinical euphoria and polarization vis-a-vis newer possibilities for resolving the predicaments of partial or complete edentulism.
(7) who was thinking about voting yes, and went on to reduce her political predicament to her meagre wage packet.
(8) Craving boldness is too often a euphemism for wishing Labour's predicament were something other than what it is; that there was a way to promise immediate improvement in everyone's lives without giving them money.
(9) When there was no accordance, we noticed a correlation between pressure gradient and surgical success in 3 cases and predicaments based on PRA and success in 2 cases.
(10) But the predicament is partly engendered by prosperity, too.
(11) The Canadian researchers were more sympathetic to the IGDA’s predicament than Kazemi or the workers spoken to for this feature.
(12) The former chairman blamed "mismanagement" for the retailer's dire predicament, and is interested in acquiring some of its stores to add to his DW Sports Fitness chain.
(13) Jack is played with dreamy intensity and later (as the realities of criminal life begin to kick in) with steely resolve by LaBeouf, who must be able to sympathise with Jack's predicament.
(14) If you pull one side, your feet are in the cold.” Quite how long Hazard – who did manage seven minutes off the bench – is shivering out in the wilderness remains to be seen but Chelsea’s predicament requires a creative talent who signed a new five-and-a-half-year contract in February to emulate Willian and Pedro, allying discipline to those mind-boggling flashes of skill.
(15) Caroline Lucas MEP is leader of the British Green party President Mohamed Nasheed Despite our predicament, I'm optimistic The Maldives doesn't look like the front line in a battle.
(16) If [policing is] the only type of process that they want to put in place to address these issues, then we will have a major concern with it, because that will not … address the issues and we will be in the same predicament a month from now or a year from now,” Dandan said.
(17) But, despite the sympathy felt by many in Europe for Scotland’s predicament, Sturgeon’s hopes of ensuring the country remains in the bloc look likely to be crushed.
(18) We have to try and find a way to help the audience sympathise with his predicament."
(19) So the first problem was that the Greek cuts led to a worsening of the Greek predicament: the economy kept contracting, and unemployment hit a record high of 16.2%.
(20) Until we are mathematically gone, I will believe.” Tottenham’s Son Heung-min grabs late winner after Watford red card Read more He also said he will do his utmost to entice reinforcements during the January transfer window, but admits that the club’s predicament complicates recruitment.