(v. t.) To tie, or confine with a cord, band, ligature, chain, etc.; to fetter; to make fast; as, to bind grain in bundles; to bind a prisoner.
(v. t.) To confine, restrain, or hold by physical force or influence of any kind; as, attraction binds the planets to the sun; frost binds the earth, or the streams.
(v. t.) To cover, as with a bandage; to bandage or dress; -- sometimes with up; as, to bind up a wound.
(v. t.) To make fast ( a thing) about or upon something, as by tying; to encircle with something; as, to bind a belt about one; to bind a compress upon a part.
(v. t.) To prevent or restrain from customary or natural action; as, certain drugs bind the bowels.
(v. t.) To protect or strengthen by a band or binding, as the edge of a carpet or garment.
(v. t.) To sew or fasten together, and inclose in a cover; as, to bind a book.
(v. t.) Fig.: To oblige, restrain, or hold, by authority, law, duty, promise, vow, affection, or other moral tie; as, to bind the conscience; to bind by kindness; bound by affection; commerce binds nations to each other.
(v. t.) To bring (any one) under definite legal obligations; esp. under the obligation of a bond or covenant.
(v. t.) To place under legal obligation to serve; to indenture; as, to bind an apprentice; -- sometimes with out; as, bound out to service.
(v. i.) To tie; to confine by any ligature.
(v. i.) To contract; to grow hard or stiff; to cohere or stick together in a mass; as, clay binds by heat.
(v. i.) To be restrained from motion, or from customary or natural action, as by friction.
(v. i.) To exert a binding or restraining influence.
(n.) That which binds or ties.
(n.) Any twining or climbing plant or stem, esp. a hop vine; a bine.
(n.) Indurated clay, when much mixed with the oxide of iron.
(n.) A ligature or tie for grouping notes.
Example Sentences:
(1) Tryptic digestion of the membranes caused complete disappearance of the binding activity, but heat-treatment for 5 min at 70 degrees C caused only 40% loss of activity.
(2) Comparison of the S100 alpha-binding protein profiles in fast- and slow-twitch fibers of various species revealed few, if any, species- or fiber type-specific S100 binding proteins.
(3) Competition with the labelled 10B12 MAb for binding to the purified antigen was demonstrated in sera of tumor-bearing and immune rats.
(4) These studies led to the following conclusions: (a) all the prominent NHP which remain bound to DNA are also present in somewhat similar proportions in the saline-EDTA, Tris, and 0.35 M NaCl washes of nuclei; (b) a protein comigrating with actin is prominent in the first saline-EDTA wash of nuclei, but present as only a minor band in the subsequent washes and on washed chromatin; (c) the presence of nuclear matrix proteins in all the nuclear washes and cytosol indicates that these proteins are distributed throughout the cell; (d) a histone-binding protein (J2) analogous to the HMG1 protein of K. V. Shooter, G.H.
(5) Power urges the security council to "take the kind of credible, binding action warranted."
(6) The binding properties of formalin-fixed amelanotic melanoma cells were not identical to those of endothelial or unfixed target cells.
(7) Such an increase in antibody binding occurred simultaneously with an increase in the fluidity of surface lipid regions, as monitored by fluorescence depolarization of 1-(trimethylammoniophenyl)-6-phenyl-1,3,5-hexatriene.
(8) It has been generally believed that the ligand-binding of steroid hormone receptors triggers an allosteric change in receptor structure, manifested by an increased affinity of the receptor for DNA in vitro and nuclear target elements in vivo, as monitored by nuclear translocation.
(9) Lp(a) also complexes to plasmin-fibrinogen digests, and binding increases in proportion to the time of plasmin-induced fibrinogen degradation.
(10) Theoretical computations are performed of the intercalative binding of the neocarzinostatin chromophore (NCS) with the double-stranded oligonucleotides d(CGCG)2, d(GCGC)2, d(TATA)2 and d(ATAT)2.
(11) The LD50 of the following metal-binding chelating drugs, EDTA, diethylenetriaminepentaacetic acid (DTPA), hydroxyethylenediaminetriacetic acid (HEDTA), cyclohexanediaminotetraacetic acid (CDTA) and triethylenetetraminehexaacetic acid (TTHA) was evaluated in terms of mortality in rats after intraperitoneal administration and was found to be in the order: CDTA greater than EDTA greater than DTPA greater than TTHA greater than HEDTA.
(12) It was also able to inhibit the binding both of alpha-bungarotoxin and rabies virus glycoprotein to the acetylcholine receptor.
(13) We report a series of experiments designed to determine if agents and conditions that have been reported to alter sodium reabsorption, Na-K-ATPase activity or cellular structure in the rat distal nephron might also regulate the density or affinity of binding of 3H-metolazone to the putative thiazide receptor in the distal nephron.
(14) The procedure used in our laboratory was not able to provide accurate determination of the concentrations of these binding forms.
(15) The occupation of the high affinity calcium binding site by Ca(II) and Mn(II) does not influence the Cu(II) binding process, suggesting that there is no direct interaction between this site and the Cu(II) binding sites.
(16) PMN were found to be nonpermissive for HSV replication and were unable to bind virus in the absence of antibody.
(17) Radioligand binding studies revealed the presence of a single class of high-affinity (Kd = 2-6 X 10(-10) M) binding sites for ET-1 in both cells, although the maximal binding capacity of cardiac receptor was about 6- to 12-fold greater than that of vascular receptor.
(18) The transported pIgA was functional, as evidenced by its ability to bind to virus in an ELISA assay and to protect nonimmune mice against intranasal infection with H1N1 but not H3N2 influenza virus.
(19) The monoclonal antibody (mAb), SY38, binds to a cytoplasmic domain of synaptophysin.
(20) Binding data for both ligands to the enzyme yielded nonlinear Scatchard plots that analyze in terms of four negatively cooperative binding sites per enzyme tetramer.
Testify
Definition:
(v. i.) To make a solemn declaration, verbal or written, to establish some fact; to give testimony for the purpose of communicating to others a knowledge of something not known to them.
(v. i.) To make a solemn declaration under oath or affirmation, for the purpose of establishing, or making proof of, some fact to a court; to give testimony in a cause depending before a tribunal.
(v. i.) To declare a charge; to protest; to give information; to bear witness; -- with against.
(v. t.) To bear witness to; to support the truth of by testimony; to affirm or declare solemny.
(v. t.) To affirm or declare under oath or affirmation before a tribunal, in order to prove some fact.
(adv.) In a testy manner; fretfully; peevishly; with petulance.
Example Sentences:
(1) Right hemisphere inactivation caused a decrease in the frequency of lateral hypothalamus self-stimulation, whereas with left hemisphere inactivation it increased, which testifies to right hemisphere dominance in self-stimulation reaction.
(2) Both Murdoch and his son James were called to testify before parliament.
(3) "It is very easy to see somebody get killed over this issue," Marijuana Industry Group Director Michael Elliott testified last month.
(4) The data obtained testify to the presence in the granular fraction of the endopeptidase LTH-converting activity which is sensitive to pepstatin A, an aspartyl proteinase inhibitor as well as to chelators and a serine proteinase inhibitor.
(5) Asymmetry was revealed with predominance of the amplitude increase in the right hemisphere in the phase of the rapid sleep testifying to different roles of the cerebral hemispheres in processing of emotionally significant information.
(6) The many surgical procedures that have been proposed testify to the fact that no single reliable procedure has been developed.
(7) The biggest deviation of indexes, that testifies about metabolic changes comes to 9-14%, and immunobiological changes-up to 20-33%.
(8) The experimental curves plotted in the Scatchard coordinates testify to the presence in thromboplastin of two types of fragment I binding sites: those with a high (Kd = 7.6 x 10(-6) M) and moderate (Kd = 1.3 x 10(-8) M) binding affinity.
(9) He was also accused separately of obstruction of justice over allegations he tried to persuade a former aide not to testify against him.
(10) The results obtained testify to the considerable contribution of [3-14C] tryptophan and [2-14C] alanine to protein synthesis as well as to their involvement in the substrate supply of lipogenesis and energetic processes in various organs and tissues of cattle.
(11) On Sunday, there was an expectation that the trial could be extended after Olmert's long-time aide Shula Zaken turned state's witness and agreed to testify against him.
(12) He has, however, refused to testify, invoking his right to remain silent, while his lawyer has insisted his client is “insane” and therefore unfit for trial.
(13) Subjects with a desynchronized EEG differ from those with alpha-rhythm predominance by the highest coherence and similarity of the spectra along with their low stability in the anterior parts of the hemisphere which testifies to a high dynamic integration of the frontal systems.
(14) The prosecution claimed that before the trial, both Humphrey and Yu testified to police that they knew the company was operating in a legal "grey zone".
(15) And lest there be any remaining doubt, a forensic expert on maggots – such people do exist – testified that the theory of "semen-destroying maggots" was balderdash.
(16) Testifying before the Senate judiciary committee on Wednesday, John Lewis, a congressman from Georgia, said the court's ruling had left him devastated.
(17) British spies don wigs and makeup to testify at US trial of al-Qaida suspect Read more Abid Naseer was first arrested in 2009 in Britain on charges that he was part of a terror cell plotting to blow up a shopping mall in Manchester, England.
(18) His report, which has been obtained by The Observer, shows that Mubanga had asked for his sister, aunt and brother to testify in his defence.
(19) He also thanked nearly everyone who had been involved in the trial: his attorneys, his family, everyone who testified “with dignity” about their “unbearable” hardships.
(20) He had raised the possibility of calling witnesses to testify "if it really is the case that legitimate lobbyists could be paid 30% of the value of a $40m contract simply as recompense for their time and trouble".