(n.) The act or process of one who, or that which, binds.
(n.) Anything that binds; a bandage; the cover of a book, or the cover with the sewing, etc.; something that secures the edge of cloth from raveling.
(pl.) The transoms, knees, beams, keelson, and other chief timbers used for connecting and strengthening the parts of a vessel.
Example Sentences:
(1) Tryptic digestion of the membranes caused complete disappearance of the binding activity, but heat-treatment for 5 min at 70 degrees C caused only 40% loss of activity.
(2) Comparison of the S100 alpha-binding protein profiles in fast- and slow-twitch fibers of various species revealed few, if any, species- or fiber type-specific S100 binding proteins.
(3) Competition with the labelled 10B12 MAb for binding to the purified antigen was demonstrated in sera of tumor-bearing and immune rats.
(4) These studies led to the following conclusions: (a) all the prominent NHP which remain bound to DNA are also present in somewhat similar proportions in the saline-EDTA, Tris, and 0.35 M NaCl washes of nuclei; (b) a protein comigrating with actin is prominent in the first saline-EDTA wash of nuclei, but present as only a minor band in the subsequent washes and on washed chromatin; (c) the presence of nuclear matrix proteins in all the nuclear washes and cytosol indicates that these proteins are distributed throughout the cell; (d) a histone-binding protein (J2) analogous to the HMG1 protein of K. V. Shooter, G.H.
(5) Power urges the security council to "take the kind of credible, binding action warranted."
(6) The binding properties of formalin-fixed amelanotic melanoma cells were not identical to those of endothelial or unfixed target cells.
(7) Such an increase in antibody binding occurred simultaneously with an increase in the fluidity of surface lipid regions, as monitored by fluorescence depolarization of 1-(trimethylammoniophenyl)-6-phenyl-1,3,5-hexatriene.
(8) It has been generally believed that the ligand-binding of steroid hormone receptors triggers an allosteric change in receptor structure, manifested by an increased affinity of the receptor for DNA in vitro and nuclear target elements in vivo, as monitored by nuclear translocation.
(9) Lp(a) also complexes to plasmin-fibrinogen digests, and binding increases in proportion to the time of plasmin-induced fibrinogen degradation.
(10) Theoretical computations are performed of the intercalative binding of the neocarzinostatin chromophore (NCS) with the double-stranded oligonucleotides d(CGCG)2, d(GCGC)2, d(TATA)2 and d(ATAT)2.
(11) The LD50 of the following metal-binding chelating drugs, EDTA, diethylenetriaminepentaacetic acid (DTPA), hydroxyethylenediaminetriacetic acid (HEDTA), cyclohexanediaminotetraacetic acid (CDTA) and triethylenetetraminehexaacetic acid (TTHA) was evaluated in terms of mortality in rats after intraperitoneal administration and was found to be in the order: CDTA greater than EDTA greater than DTPA greater than TTHA greater than HEDTA.
(12) It was also able to inhibit the binding both of alpha-bungarotoxin and rabies virus glycoprotein to the acetylcholine receptor.
(13) We report a series of experiments designed to determine if agents and conditions that have been reported to alter sodium reabsorption, Na-K-ATPase activity or cellular structure in the rat distal nephron might also regulate the density or affinity of binding of 3H-metolazone to the putative thiazide receptor in the distal nephron.
(14) The procedure used in our laboratory was not able to provide accurate determination of the concentrations of these binding forms.
(15) The occupation of the high affinity calcium binding site by Ca(II) and Mn(II) does not influence the Cu(II) binding process, suggesting that there is no direct interaction between this site and the Cu(II) binding sites.
(16) PMN were found to be nonpermissive for HSV replication and were unable to bind virus in the absence of antibody.
(17) Radioligand binding studies revealed the presence of a single class of high-affinity (Kd = 2-6 X 10(-10) M) binding sites for ET-1 in both cells, although the maximal binding capacity of cardiac receptor was about 6- to 12-fold greater than that of vascular receptor.
(18) The transported pIgA was functional, as evidenced by its ability to bind to virus in an ELISA assay and to protect nonimmune mice against intranasal infection with H1N1 but not H3N2 influenza virus.
(19) The monoclonal antibody (mAb), SY38, binds to a cytoplasmic domain of synaptophysin.
(20) Binding data for both ligands to the enzyme yielded nonlinear Scatchard plots that analyze in terms of four negatively cooperative binding sites per enzyme tetramer.
Element
Definition:
(n.) One of the simplest or essential parts or principles of which anything consists, or upon which the constitution or fundamental powers of anything are based.
(n.) One of the ultimate, undecomposable constituents of any kind of matter. Specifically: (Chem.) A substance which cannot be decomposed into different kinds of matter by any means at present employed; as, the elements of water are oxygen and hydrogen.
(n.) One of the ultimate parts which are variously combined in anything; as, letters are the elements of written language; hence, also, a simple portion of that which is complex, as a shaft, lever, wheel, or any simple part in a machine; one of the essential ingredients of any mixture; a constituent part; as, quartz, feldspar, and mica are the elements of granite.
(n.) One out of several parts combined in a system of aggregation, when each is of the nature of the whole; as, a single cell is an element of the honeycomb.
(n.) One of the smallest natural divisions of the organism, as a blood corpuscle, a muscular fiber.
(n.) One of the simplest essential parts, more commonly called cells, of which animal and vegetable organisms, or their tissues and organs, are composed.
(n.) An infinitesimal part of anything of the same nature as the entire magnitude considered; as, in a solid an element may be the infinitesimal portion between any two planes that are separated an indefinitely small distance. In the calculus, element is sometimes used as synonymous with differential.
(n.) Sometimes a curve, or surface, or volume is considered as described by a moving point, or curve, or surface, the latter being at any instant called an element of the former.
(n.) One of the terms in an algebraic expression.
(n.) One of the necessary data or values upon which a system of calculations depends, or general conclusions are based; as, the elements of a planet's orbit.
(n.) The simplest or fundamental principles of any system in philosophy, science, or art; rudiments; as, the elements of geometry, or of music.
(n.) Any outline or sketch, regarded as containing the fundamental ideas or features of the thing in question; as, the elements of a plan.
(n.) One of the simple substances, as supposed by the ancient philosophers; one of the imaginary principles of matter.
(n.) The four elements were, air, earth, water, and fire
(n.) the conditions and movements of the air.
(n.) The elements of the alchemists were salt, sulphur, and mercury.
(n.) The whole material composing the world.
(n.) The bread and wine used in the eucharist or Lord's supper.
(v. t.) To compound of elements or first principles.
(v. t.) To constitute; to make up with elements.
Example Sentences:
(1) Elements in the skin therefore seemed to enhance nerve regeneration and function.
(2) It has been generally believed that the ligand-binding of steroid hormone receptors triggers an allosteric change in receptor structure, manifested by an increased affinity of the receptor for DNA in vitro and nuclear target elements in vivo, as monitored by nuclear translocation.
(3) Four other independent LCMV-GP2(275-289) specific H-2Db-restricted CTL clones also expressed V alpha 4 and V beta 10 gene elements.
(4) Community involvement is a key element of the Primary Health Care (PHC) approach, and thus an essential topic on a course for managers of Primary Health Care programmes.
(5) Thus, human bronchial epithelial cells can express the IL-8 gene, with expression in response to the inflammatory mediator TNF regulated mainly at the transcriptional level, and with elements within the 5'-flanking region of the gene that are directly or indirectly modulated by the TNF signal.
(6) According to the finite element analysis, the design bases of fixed restorations applied in the teeth accompanied with the absorption of the alveolar bone were preferred.
(7) To determine the influence of cetylpyridinium chloride (CPC) adsorption on the wettability and elemental surface composition of human enamel, with and without adsorbed salivary constituents, surface-free energies and elemental compositions were determined.
(8) Second, the unknown is searched against the database to find all materials with the same or similar element types; the results are kept in set 2.
(9) It is concluded that selection against insertional mutations is unlikely to be the major factor involved in the containment of element abundance.
(10) We have investigated interactions between the erythroid transcription factor GATA-1 and factors binding two cis-acting elements commonly linked to GATA sites in erythroid control elements.
(11) Further, Tyr 20 is an important element of that sequence.
(12) It is possible that the elements provide common precursor proteins that reach the secretory intermediate lobe cells through their dendritic branches.
(13) Other than failing to get a goal, I couldn’t ask for anything more.” From Lambert’s perspective there was an element of misfortune about the first and third goals, with Willian benefitting from handy ricochets on both occasions.
(14) These data indicate that the sfrB gene product is a regulatory element, since the single gene product elicits the expression of genes for many products for F expression and lipopolysaccharide synthesis.
(15) Therefore, a hormonal regulatory element can discriminate among closely related transcription start sites.
(16) The safe motherhood initiative demands an intersectoral, collaborative approach to gynecology, family planning, and child health in which midwifery is the key element.
(17) The 500-bp element arose by duplication of one half of a 180-bp ancestor and insertion of a foreign segment between the two duplicated parts followed by amplification.
(18) Neither light nor electron microscopy revealed significant morphologic alterations in the cochlear elements of the exposed offspring.
(19) The hypothesis that the standard acoustic startle habituation paradigm contains the elements of Pavlovian fear conditioning was tested.
(20) Autopsy revealed a primary intimal sarcoma with osteogenic elements arising in the posterior leaflet of the pulmonary valve and obstructing the main pulmonary artery and its right branch.