(1) We examined the biogenesis of alpha- and beta-tubulin in rabbit reticulocyte lysate, and report here that newly translated tubulin subunits entered a 900K complex in a protease-sensitive conformation.
(2) There were 2 apparent distinct phases in mitochondrial biogenesis: replication during cell proliferation and maturation during cell differentiation.
(3) This review presents an overview of the mechanisms modulating the production of ribosomal precursor molecules and the rate of ribosome biogenesis in various biological systems.
(4) The effect of PMA has been investigated at each stage of TNF alpha biogenesis.
(5) The degree of S-pilin processing and the levels of membrane-associated pilin varied among the different classes of mutants, suggesting that each was blocked at a distinct step of pilus biogenesis.
(6) Segregation of glycolytic enzymes into glycosomes raises questions concerning the distribution and biogenesis of these organelles.
(7) The owner of Biogenesis, the now-closed Florida anti-aging clinic , said in an interview with CBS TV show "60 Minutes" that the 38-year-old sportsman paid him $12,000 per month for an assortment of banned drugs including testosterone and human growth hormone.
(8) Re-feeding starved rats increased the biogenesis of sterols in livers, with highest activity at 6h after the start of food intake.
(9) The observation that peroxisomes of Saccharomyces cerevisiae can be induced by oleic acid has opened the possibility to investigate the biogenesis of these organelles in a biochemically and genetically well characterized organism.
(10) This review deals with the biogenesis of MP26 and with the problem of the structural pattern which may be formed by MP26 during differentiation and aging of the lens fibers and as a consequence of the extraction or degradation of other membrane components.
(11) Tonic contractile activity induces mitochondrial biogenesis in mammalian skeletal muscles, necessitating regulation of both nuclear and mitochondrial genes encoding mitochondrial proteins.
(12) Our results suggest a mechanism for hepatocyte plasma membrane biogenesis in vivo in which all integral plasma membrane proteins are shipped first to the basolateral domain, followed by the specific retrieval and transport of apical proteins to the apical domain at distinct rates.
(13) We studied the effects of FAD at various stages of acyl-CoA dehydrogenase biogenesis.
(14) The availability of the genetic approach has led to molecular insights concerning the mechanisms of vesicle biogenesis, targeting and fusion.
(15) He was suspended for the entire 2014 season for his part in the Biogenesis scandal , in which MLB players were accused of involvement with performance enhancing drugs allegedly supplied by the now defunct South Florida anti-aging clinic.
(16) The effects of aldosterone on transepithelial sodium transport (measured by the short-circuit current (SCC) and on Na+-K+-adenosine triphosphatase (ATPase) biogenesis have been studied in A6 kidney cells grown on collagen-coated filters in two different media.
(17) The kinetics of ethylene biogenesis and its pH and temperature optima suggest that ethylene is a secondary metabolite.
(18) The fact that ethylene was produced by the yeast growing anaerobically and also by respiration-deficient mutants isolated from the wild-type yeast suggested that mitochondrial ATP synthesis was not an absolute requirement for ethylene biogenesis.
(19) Thiolase biogenesis thus differs from that of rat liver peroxisomal proteins studied previously in that it is synthesized as a larger precursor, implying post-translational import of thiolase into peroxisomes with proteolytic processing.
(20) Our results demonstrate that the regenerating peripheral nerve possesses the components of a cholesterol transfer mechanism, and the sequence of events suggests that this mechanism supplies the cholesterol required for rapid membrane biogenesis during axon regeneration and remyelination.
Principle
Definition:
(n.) Beginning; commencement.
(n.) A source, or origin; that from which anything proceeds; fundamental substance or energy; primordial substance; ultimate element, or cause.
(n.) An original faculty or endowment.
(n.) A fundamental truth; a comprehensive law or doctrine, from which others are derived, or on which others are founded; a general truth; an elementary proposition; a maxim; an axiom; a postulate.
(n.) A settled rule of action; a governing law of conduct; an opinion or belief which exercises a directing influence on the life and behavior; a rule (usually, a right rule) of conduct consistently directing one's actions; as, a person of no principle.
(n.) Any original inherent constituent which characterizes a substance, or gives it its essential properties, and which can usually be separated by analysis; -- applied especially to drugs, plant extracts, etc.
(v. t.) To equip with principles; to establish, or fix, in certain principles; to impress with any tenet, or rule of conduct, good or ill.
Example Sentences:
(1) Stress is laid on certain principles of diagnostic research in the event of extra-suprarenal pheochromocytomas.
(2) However, as the same task confronts the Lib Dems, do we not now have a priceless opportunity to bring the two parties together to undertake a fundamental rethink of the way social democratic principles and policies can be made relevant to modern society.
(3) To a supporter at the last election like me – someone who spoke alongside Nick Clegg at the curtain-raiser event for the party conference during the height of Labour's onslaught on civil liberties, and was assured privately by two leaders that the party was onside about civil liberties – this breach of trust and denial of principle is astonishing.
(4) The White House denied there had been an agreement, but said it was open in principle to such negotations.
(5) Using the MTT assay and analyzing the data using the median-effect principle, we showed that synergistic cytotoxic interactions exist between CDDP and VM in their liposomal form.
(6) The heretofore "permanently and totally disabled versus able-bodied" principle in welfare reforms is being abbandoned.
(7) The binding follows the principle of isotope dilution in the physiologic range of vitamin B12 present in human serum.
(8) The principle of the liquid and solid two-phase radioimmunoassay and its application to measuring the concentrations of triiodothyronine and thyroxine of human serum in a single sample at the same time are described in this paper.
(9) Spectrophotometric tests for the presence of a lysozyme-like principle in the serum also revealed similar trends with a significant loss of enzyme activity in 2,4,5-T-treated insects.
(10) All these strains produced an enterotoxic principle, antigenically related to cholera coli family of enterotoxins, as detected by latex agglutination and immuno-dot-blot tests.
(11) The basic principle of the resonant tool, its adaptation for surgery, the experimental results of its use in animals, and clinical experience are reported.
(12) It seems tragic, then, that so little of these principles transfer over to the container in which the work is done.
(13) This conception of the city as an expression of both regal power and social order, guided by cosmological principles and the pursuit of yin-yang equilibrium, was unlike anything in the western tradition.
(14) The general principles of bypass surgery as they affect the cerebral circulation are reviewed.
(15) The interest of this view resides in the resulting general principle of classification and interpretation of all forms of disease, giving rise to an "existenialistic pathology".
(16) Eight of the UK's biggest supermarkets have signed up to a set of principles following concerns that they were "failing to operate within the spirit of the law" over special offers and promotions for food and drink, the Office of Fair Trading has said.
(17) Although the general guiding principle of pharmacotherapy for anxiety disorders--the lowest effective dose for the shortest possible time--remains, this rule should not interfere with the judicious use of medications as long as the benefits justify it.
(18) In older stages, the cervical joints rotate according to geometric and lever arm principles.
(19) Spain’s constitutional court responded by unanimously ruling that the legislation had ignored and infringed the rules of the 1978 constitution , adding that the “principle of democracy cannot be considered to be separate from the unconditional primacy of the constitution”.
(20) The principles and practice of aneasthesia for patients having coronary bypass grafts are discussed.