(n.) A small European minnow (Leuciscus phoxinus).
Example Sentences:
(1) The inhibitors tested in order of their decreasing effectiveness were alpha-1-proteinase inhibitor (alpha-1-antitrypsin), lima bean trypsin inhibitor, soybean trypsin inhibitor, Bowman-Birk (soybean) inhibitor, Kunitz pancreatic trypsin inhibitor, porcine Kazal inhibitor, and chicken ovomucoid.
(2) A bicyclic hexadecapeptide, which corresponds to the sequence 36-51 and contains the chymotrypsin-reactive Leu-43-Ser-44 bond of soybean Bowman-Birk inhibitor, has been synthesized.
(3) Fifty-five 7-week-old male mice were randomized into 11 groups and gavaged 5 days per week with purified Bowman-Birk inhibitor, Bowman-Birk inhibitor concentrate, and autoclaved Bowman-Birk inhibitor concentrate.
(4) The established sequence showed that RBTI is composed of 4 domains, domains I and III, and domains II and IV being homologous to the first and the second domains of soybean Bowman-Birk inhibitor, respectively, indicating that RBTI has a duplicated structure of the Bowman-Birk type inhibitor.
(5) There are regions of high conservation and high divergence within the 5' leader, mature protein and 3' non-coding regions of the Bowman-Birk inhibitors and in the genes which encode them in different members of this family within the Leguminosae.
(6) Therefore, R-BIRK functions as a basal-state enzyme and can be stimulated in an insulin-like manner.
(7) Inhibitor C-II was found to be homologous with soybean (Glycine max) Bowman-Birk inhibitor and more closely related to an inhibitor from garden beans (Phaseolus vulgaris).
(8) The structure determination and refinement are described, and the structure is compared to other structures of Bowman-Birk inhibitors as well as other families of serine protease inhibitors.
(9) The three-dimensional structure of the Bowman-Birk type proteinase inhibitor (PI-II) has been determined by x-ray crystallography and refined at 2.5-A resolution.
(10) Previous studies have demonstrated that the soybean-derived Bowman-Birk protease inhibitor (BBI) is effective as a cancer chemopreventive agent in several animal model systems.
(11) The trypsin-chymotrypsin inhibitors from dog submandibular glands, from soybeans (Bowman-Birk) and from chickpeas show strong interaction with these proteases (Ki = 10(-8) - 10(-9)M).
(12) Birke and Sadler (1983) showed that not only perinatal androgens but also progestogens such as medroxyprogesterone acetate (MPA) affect (in this case: demasculinize) the play behavior of both sexes in the rat.
(13) The effect of pH and temperature on the apparent association equilibrium constant (Ka) for the binding of the soybean Bowman-Birk proteinase inhibitor (BBI) and of its chymotrypsin and trypsin inhibiting fragments (F-C(p), F-T(p) and F-T(t), respectively) to bovine alpha-chymotrypsin (alpha-chymotrypsin) and bovine beta-trypsin (beta-trypsin) has been investigated.
(14) In the assay of two soybean trypsin inhibitors, the Kunitz and the Bowman-Birk inhibitors, two procedures were used: the current procedure in which the substrate is added last (the S-last test), after inhibitor is mixed with enzyme, and a new procedure in which the enzyme is added last (the E-last test), after inhibitor is mixed with substrate.
(15) The results for the total-body-irradiated mice receiving Bowman-Birk inhibitor concentrate suggested an effect midway between these two groups.
(16) ATI is the first Bowman-Birk inhibitor that has been found in leaves and is the only member of this family known to be regulated by wounding.
(17) The enzyme is strongly inhibited by aprotinin, diisopropylfluorophosphate, antipain, leupeptin, and Kunitz-type soybean trypsin inhibitor, but inhibited only slightly by Bowman-Birk soybean trypsin inhibitor, benzamidine, and alpha 1-antitrypsin.
(18) Emma Birks, 36, was a volunteer co-ordinator at a worker's co-operative in Birmingham before deciding to go travelling in south-east Asia.
(19) This intracellular protease was inhibited by the soybean-derived Bowman-Birk inhibitor (BBI), chymostatin, and L-1-tosylamido-2-phenylethyl chloromethyl ketone, all of which have anticarcinogenic activity, but was unaffected by soybean trypsin inhibitor, which lacks anticarcinogenic activity.
(20) The soybean-derived Bowman-Birk inhibitor (BBI) has been shown to inhibit carcinogenesis in both in vitro and in vivo model systems.
Birt
Definition:
(n.) A fish of the turbot kind; the brill.
Example Sentences:
(1) We describe a patient with multiple fibrofolliculomas (FF), tricodiscomas (TD) and acrochordons (Birt-Hogg-Dubé) associated with intestinal polyps.
(2) Later, Lord Birt said he admired the "bold, buccaneering spirit" of Rupert Murdoch but warned that Sky was "a financial behemoth now dwarfing other players, including the BBC, financially".
(3) "When I joined I took the salary I was offered, which happened to be exactly the same as my predecessor [Birt] and when I left my basic salary was something like half what the current director general [Thompson] is now receiving," he said.
(4) After the John Birt regime, however, his ebullient leadership style involving "cut the crap" and "let's make it happen" initiatives was welcomed by staff,who had felt creativity had been repressed for far too long under the weight of bureaucracy.
(5) Birt recalled how Frost only got the interview with Nixon because he raised the money personally, outbidding a US broadcaster.
(6) Or the Russian model: outgoing president picks incoming president (President Birt or President Levy)?
(7) Hall became director of news and current affairs in 1990 and was regarded as one of Birt's key lieutenants after he became director general in 1992.
(8) Birt became Frost's protege and went on to produce the Nixon interviews in 1977.
(9) In 1996, a former World Service US affairs analyst Michael Moran wrote after the Birt coup, that what had been "a journalist's dream, one where more than any other organisation on this planet the inherent value of the story is what counted", had became dominated by "new-age management consultancy", managers who spoke in the jargon of producer's choice and delayering.
(10) In late 1969 or early 1970, John Birt, then an editor for Granada's World in Action (and later the director general of the BBC), interviewed Frost at the Algonquin Hotel in New York.
(11) The BBC has been sensitive to the tax status of its staff since the so-called "Armanigate" scandal in 1993, when it was revealed that then director general John Birt was actually employed on a freelance basis, through his own company, John Birt Productions.
(12) Frost's second legacy, Birt said, was he inventing the modern interview.
(13) After Alasdair Milne resigned and John Birt achieved power, this centralisation was accelerated.
(14) Hodgson was described in her former boss John Birt's memoirs as an "extraordinarily smart operator" and has the advantage that she already has experience of working within the BBC and the trust.
(15) And my anxiety is that if [the government] are going to keep on treating the chair of the BBC Trust like this through charter renewal, you’re not going to have a robust discussion, you’re going to have a caving in.” On Monday, it emerged that the BBC had agreed to shoulder the £700m cost of providing free TV licences for the over-75s from 2020 – a deal negotiated in secret, It was subsequently criticised by several former senior BBC figures including the former director general Lord Birt and the former chair Sir Christopher Bland.
(16) Two familial observations of Birt-Hogg-Dubé syndrome are reported.
(17) Now, Birt, a fellow Catholic Liverpudlian, was persuaded that Black would “keep it clean”.
(18) In fact Birt has been unfairly turned into a wicked uncle.
(19) Does £145.50 a year until 2016 fit that crucial Birt bill?
(20) It is no accident that Birt's two jobs since have been at number 10 and at McKinsey's.