(n.) A small European minnow (Leuciscus phoxinus).
Example Sentences:
(1) The inhibitors tested in order of their decreasing effectiveness were alpha-1-proteinase inhibitor (alpha-1-antitrypsin), lima bean trypsin inhibitor, soybean trypsin inhibitor, Bowman-Birk (soybean) inhibitor, Kunitz pancreatic trypsin inhibitor, porcine Kazal inhibitor, and chicken ovomucoid.
(2) A bicyclic hexadecapeptide, which corresponds to the sequence 36-51 and contains the chymotrypsin-reactive Leu-43-Ser-44 bond of soybean Bowman-Birk inhibitor, has been synthesized.
(3) Fifty-five 7-week-old male mice were randomized into 11 groups and gavaged 5 days per week with purified Bowman-Birk inhibitor, Bowman-Birk inhibitor concentrate, and autoclaved Bowman-Birk inhibitor concentrate.
(4) The established sequence showed that RBTI is composed of 4 domains, domains I and III, and domains II and IV being homologous to the first and the second domains of soybean Bowman-Birk inhibitor, respectively, indicating that RBTI has a duplicated structure of the Bowman-Birk type inhibitor.
(5) There are regions of high conservation and high divergence within the 5' leader, mature protein and 3' non-coding regions of the Bowman-Birk inhibitors and in the genes which encode them in different members of this family within the Leguminosae.
(6) Therefore, R-BIRK functions as a basal-state enzyme and can be stimulated in an insulin-like manner.
(7) Inhibitor C-II was found to be homologous with soybean (Glycine max) Bowman-Birk inhibitor and more closely related to an inhibitor from garden beans (Phaseolus vulgaris).
(8) The structure determination and refinement are described, and the structure is compared to other structures of Bowman-Birk inhibitors as well as other families of serine protease inhibitors.
(9) The three-dimensional structure of the Bowman-Birk type proteinase inhibitor (PI-II) has been determined by x-ray crystallography and refined at 2.5-A resolution.
(10) Previous studies have demonstrated that the soybean-derived Bowman-Birk protease inhibitor (BBI) is effective as a cancer chemopreventive agent in several animal model systems.
(11) The trypsin-chymotrypsin inhibitors from dog submandibular glands, from soybeans (Bowman-Birk) and from chickpeas show strong interaction with these proteases (Ki = 10(-8) - 10(-9)M).
(12) Birke and Sadler (1983) showed that not only perinatal androgens but also progestogens such as medroxyprogesterone acetate (MPA) affect (in this case: demasculinize) the play behavior of both sexes in the rat.
(13) The effect of pH and temperature on the apparent association equilibrium constant (Ka) for the binding of the soybean Bowman-Birk proteinase inhibitor (BBI) and of its chymotrypsin and trypsin inhibiting fragments (F-C(p), F-T(p) and F-T(t), respectively) to bovine alpha-chymotrypsin (alpha-chymotrypsin) and bovine beta-trypsin (beta-trypsin) has been investigated.
(14) In the assay of two soybean trypsin inhibitors, the Kunitz and the Bowman-Birk inhibitors, two procedures were used: the current procedure in which the substrate is added last (the S-last test), after inhibitor is mixed with enzyme, and a new procedure in which the enzyme is added last (the E-last test), after inhibitor is mixed with substrate.
(15) The results for the total-body-irradiated mice receiving Bowman-Birk inhibitor concentrate suggested an effect midway between these two groups.
(16) ATI is the first Bowman-Birk inhibitor that has been found in leaves and is the only member of this family known to be regulated by wounding.
(17) The enzyme is strongly inhibited by aprotinin, diisopropylfluorophosphate, antipain, leupeptin, and Kunitz-type soybean trypsin inhibitor, but inhibited only slightly by Bowman-Birk soybean trypsin inhibitor, benzamidine, and alpha 1-antitrypsin.
(18) Emma Birks, 36, was a volunteer co-ordinator at a worker's co-operative in Birmingham before deciding to go travelling in south-east Asia.
(19) This intracellular protease was inhibited by the soybean-derived Bowman-Birk inhibitor (BBI), chymostatin, and L-1-tosylamido-2-phenylethyl chloromethyl ketone, all of which have anticarcinogenic activity, but was unaffected by soybean trypsin inhibitor, which lacks anticarcinogenic activity.
(20) The soybean-derived Bowman-Birk inhibitor (BBI) has been shown to inhibit carcinogenesis in both in vitro and in vivo model systems.
Minnow
Definition:
(n.) A small European fresh-water cyprinoid fish (Phoxinus laevis, formerly Leuciscus phoxinus); sometimes applied also to the young of larger kinds; -- called also minim and minny. The name is also applied to several allied American species, of the genera Phoxinus, Notropis, or Minnilus, and Rhinichthys.
(n.) Any of numerous small American cyprinodont fishes of the genus Fundulus, and related genera. They live both in fresh and in salt water. Called also killifish, minny, and mummichog.
Example Sentences:
(1) This has been a really fascinating half of football: the favourites finally showing some real class up front, the minnows digging deep in defence and occasionally breaking forward.
(2) Forty-thousand fans had packed the Zhuque Stadium in the northern city of Xi’an to see China, ranked 78th in the world by Fifa, take on Syria , a footballing minnow ranked 114th, just ahead of Turkmenistan, Lithuania, Palestine and North Korea.
(3) Unfortunately, it’s only a £20m minnow, so we took a look at the big funds instead.
(4) Fat head minnows, 45-days old, were continuously exposed to DDT using continuous water flow and constant temperature conditions.
(5) Synthesis and maturation of frog virus 3 deoxyribonucleic acid (DNA) in BHK cells and selected variants, in chick fibroblasts, and in minnow cells were compared.
(6) Three simulated marsh systems were constructed, containing sediment, marsh plants, oysters, blue crabs, fiddler crabs, and two species of top minnows.
(7) The toxicity of natural pyrethrins and five pyrethroids was determined with coho salmon (Oncorhynchus kisutch), steelhead trout (Salmo gairdneri), fathead minnow (Pimephales promelas), channel catfish (Icatlurus punctatus), bluegill (Lepomis macrochirus), and yellow perch (Perca flavescens).
(8) It was found that in the gills of minnow, the other mass fish in the northern rivers of the USSR, larvae of M. margaritifera cannot develop and perish.
(9) Sheepshead minnows (Cyprinodon variegatus) were least affected by mirex.
(10) But in soccer, their team has never before been larger than a minnow.
(11) The viral susceptibility range of a poikilothermic cell line derived from the fathead minnow (Pimephales promelas) (FHM) to infection by a number of homoiothermic viruses representing most of the presently recognized viral groups and a member of the psittacosis-lymphogranuloma-trachoma group of agents was studied.
(12) Putative cholinergic neurons in the photosensory pineal organ of a cyprinid teleost, the European minnow, were studied by use of choline acetyltransferase (ChAT) immunocytochemistry and acetylcholinesterase (AChE) histochemistry.
(13) From central European minnows such as Slovakia to Baltic eurozone republics such as Latvia and Lithuania , hard-pressed pensioners and workers earning barely €500 a month are at a loss as to why Greece should qualify for more largesse.
(14) Now Colombia look like another South American minnow gagging to give Brazil a good run for their money.
(15) The privately owned chain is still a relative minnow, controlling just 5.8% of all grocery sales in the UK, but only Pampers nappies are bigger sellers than its Mamia brand, and 8% of our fresh fruit and veg, and over a fifth of all premium steaks, are bought in Aldi stores.
(16) However, there was a better correlation between the in vitro cytotoxicity data for the BF-2 cell culture and LC50 data for bluegill sunfish than between similar data for the FHM cell line and fathead minnows.
(17) Following administration by gavage [75Se]selenate and [75Se]selenite were absorbed from the gastrointestinal tract of fathead minnows (Pimephales promelas) at 94 and 80% efficiency, respectively.
(18) If battle lines were not already drawn jaggedly between football’s superpowers (and its many minnows who share equal voting rights) after the damning US indictment of 18 football executives on 47 corruption charges, they certainly are now.
(19) It isn't just the minnows at the wrong end of the high street who are now on the wrong end of history.
(20) The sheepshead minnow (Cyprinodon variegatus) was continuously exposed for 23 wk to the organochlorine insecticide endrin, from the embryonic state through hatching until adulthood and spawing.