What's the difference between bitter and quinine?

Bitter


Definition:

  • (n.) AA turn of the cable which is round the bitts.
  • (v. t.) Having a peculiar, acrid, biting taste, like that of wormwood or an infusion of hops; as, a bitter medicine; bitter as aloes.
  • (v. t.) Causing pain or smart; piercing; painful; sharp; severe; as, a bitter cold day.
  • (v. t.) Causing, or fitted to cause, pain or distress to the mind; calamitous; poignant.
  • (v. t.) Characterized by sharpness, severity, or cruelty; harsh; stern; virulent; as, bitter reproach.
  • (v. t.) Mournful; sad; distressing; painful; pitiable.
  • (n.) Any substance that is bitter. See Bitters.
  • (v. t.) To make bitter.

Example Sentences:

  • (1) Since the election on 7 March there has been a bitter contest for power in Iraq led by Iran, Saudi Arabia and Turkey.
  • (2) If bitter, pour it out and measure 1.4 litres of water.
  • (3) The dumplings could also be served pan-fried in browned butter and tossed with a bitter leaf salad and fresh sheep's cheese for a lighter, but equally delicious option.
  • (4) The first was a passive avoidance task in which the chicks were allowed to peck at a green training stimulus (a small light-emitting diode, LED) coated in the bitter liquid, methylanthranilate, giving rise to a strong disgust response and consequent avoidance of the green stimulus.
  • (5) In the QHCl-sucrose condition components separated by the tongue's midline and those spatially mixed produced equal amounts of bitterness suppression.
  • (6) At the interview those with conventional ileostomies expressed better preoperative comprehension of the procedure and more satisfaction about its life-saving nature; nevertheless, they experienced more negative emotional reactions, such as bitterness, after the operation.
  • (7) The higher analogues of the cycloalkane series containing alpha-aminocycloheptanecarboxylic acid methyl ester and alpha-aminocyclooctanecarboxylic acid methyl ester are bitter.
  • (8) It's almost starting to feel like we're back in the good old days of July 2005, when Paris lost out to London in the battle to stage the 2012 Olympic Games, a defeat immediately interpreted by France as a bitter blow to Gallic ideals of fair play and non-commercialism and yet another undeserved triumph for the underhand, free-market manoeuvrings of perfidious Albion.
  • (9) Hollande ended up defending until to the bitter end Jérôme Cahuzac , a finance minister responsible for fighting tax evasion who turned out to have used a secret Swiss bank account to avoid paying taxes in France.
  • (10) The sensitivity of the taste system to the various qualities was, in decreasing order, salty, sweet, sour, and bitter.
  • (11) Grace's ascent has also thrown a grenade into the bitter succession battle within Zanu-PF, which Mugabe has divided and ruled for decades.
  • (12) Denatonium, a very bitter substance, caused a rise in the intracellular calcium concentration due to release from internal stores in a small subpopulation of taste cells.
  • (13) I see myself in exactly the same situation as I saw myself yesterday, though obviously with the bitter disappointment of the failure of being knocked out.
  • (14) Stephen Joseph, its chief executive said: "This is bitter news for everyone who relies on the train to get to work, not least the large number of commuters in marginal constituencies who will be a key group at the next election."
  • (15) Lewis Wind Power, the joint venture company set up by Amec and British Energy, said it was "bitterly disappointed" by the decision.
  • (16) As night fell in Paris, despite the bitter cold, more than 5,000 people gathered under the imposing statue of Marianne, the symbol of the republic, to show their anger, grief and solidarity.
  • (17) The present alternative model of health care in China has evolved after prolonged and often bitter debate extending over twenty years.
  • (18) It is much less soluble and bitter and poses few stability problems when capsulated or tableted with aspirin.
  • (19) "They have given Mexicans the most bitter Christmas," Armando Martínez, the president of the College of Catholic Attorneys, told reporters.
  • (20) He says he is not bitter but his words are laced with hostility.

Quinine


Definition:

  • (n.) An alkaloid extracted from the bark of several species of cinchona (esp. Cinchona Calisaya) as a bitter white crystalline substance, C20H24N2O2. Hence, by extension (Med.), any of the salts of this alkaloid, as the acetate, chloride, sulphate, etc., employed as a febrifuge or antiperiodic. Called also quinia, quinina, etc.

Example Sentences:

  • (1) The influence of the hexylsalicylic acid (2) on the pharmacokinetic of the quinine (1), was studied using rabbits.
  • (2) Concomitant with the inhibition of K+ and Na+ transport, quinine stimulates ATP hydrolysis by 57%.
  • (3) those that had entered the G1 phase) expressed an increased amount of Fc gamma RII and (b) blocking the entry of activated cells into the S phase (with the ion channel blocker quinine) did not affect the Fc gamma RII induction by LPS.
  • (4) It was found that DI rats responded less than LE rats on the progressive-ratio schedule and that DI rats suppressed drinking as much as LE rats at each concentration of quinine used on the drinking-suppression test.
  • (5) Microsomal metabolites were also isolated from quinine and quinidine incubations with rabbit or guinea pig liver fractions.
  • (6) A nearly complete blockade of channel current was observed at 100 nM quinine and above.
  • (7) Treatment may be delayed because the therapy recommended for severe or complicated disease, intravenous quinine dihydrochloride, is available only from the Centers for Disease Control.
  • (8) Cell proliferation was equally sensitive to quinine regardless of mitogen.
  • (9) The responses to quinine and mefloquine or halofantrine showed no correlation with each other.
  • (10) The CGRP-IR levels in the rostral (gustatory) part of the insular cortex were increased significantly by strongly aversive taste stimuli such as quinine hydrochloride and conditioned taste stimuli (NaCl and sucrose) which animals had been taught to avoid.
  • (11) Quinidine, the stereoisomer of quinine, had no effect on either cells from the patient or normal cells.
  • (12) Despite the presence in the region of an important resistance of Plasmodium falciparum to chloroquine (80% specimens), one can conclude to a satisfying susceptibility of this parasite to quinine, provided posology and divided doses are respected.
  • (13) The clinical application of the method for routine drug monitoring and for estimating the pharmacokinetics of quinine and quinidine in man are discussed.
  • (14) The resistance of Plasmodium falciparum, the cause of tertian malaria, to synthetic antimalarials, together with the resistance of the vector mosquitoes to insecticides, has resulted in a resurgence in the use of quinine and a search for new antimalarial agents.
  • (15) all infections were sensitive to quinine plus tetracycline.
  • (16) Quinine applied on the intracellular side of the membrane in micromolar concentrations chopped the unitary K+ currents into bursts of brief openings.
  • (17) This was shown by a dye exclusion test and by mitogen stimulation after exposure and removal of quinine from the medium.
  • (18) These are insensitive to quinine, suggesting that they are not caused by an intracellular Ca accumulation.
  • (19) The spread of chloroquine-resistant malaria has led to a resurgence of quinine in clinical use.
  • (20) Whether it was Sénac or Wenckebach who first observed that quinine could change an irregular heart rhythm (atrial fibrillation) into a regular one (sinus rhythm), we are not far from their empiricism.