(n.) A forcible stream of air from an orifice, as from a bellows, the mouth, etc. Hence: The continuous blowing to which one charge of ore or metal is subjected in a furnace; as, to melt so many tons of iron at a blast.
(n.) The exhaust steam from and engine, driving a column of air out of a boiler chimney, and thus creating an intense draught through the fire; also, any draught produced by the blast.
(n.) The sound made by blowing a wind instrument; strictly, the sound produces at one breath.
(n.) A sudden, pernicious effect, as if by a noxious wind, especially on animals and plants; a blight.
(n.) The act of rending, or attempting to rend, heavy masses of rock, earth, etc., by the explosion of gunpowder, dynamite, etc.; also, the charge used for this purpose.
(n.) A flatulent disease of sheep.
(v. t.) To injure, as by a noxious wind; to cause to wither; to stop or check the growth of, and prevent from fruit-bearing, by some pernicious influence; to blight; to shrivel.
(v. t.) Hence, to affect with some sudden violence, plague, calamity, or blighting influence, which destroys or causes to fail; to visit with a curse; to curse; to ruin; as, to blast pride, hopes, or character.
(v. t.) To confound by a loud blast or din.
(v. t.) To rend open by any explosive agent, as gunpowder, dynamite, etc.; to shatter; as, to blast rocks.
(v. i.) To be blighted or withered; as, the bud blasted in the blossom.
(v. i.) To blow; to blow on a trumpet.
Example Sentences:
(1) A Swedish news agency said it had received an email warning before the blasts in which a threat was made against Sweden's population, linked to the country's military presence in Afghanistan and the five-year-old case of caricatures of the prophet Muhammad by Swedish artist Lars Vilks.
(2) Moments later, explosive charges blasted free two tungsten blocks, to shift the balance of the probe so it could fly itself to a prearranged landing spot .
(3) However, the blasts formed mixed colonies consisting of erythroblasts, granulocytes, macrophages, and immature blasts when cultured in methylcellulose with PHA-leukocyte conditioned medium.
(4) A proportion of blasts from five of 10 cases of AML expressed receptors for IL-2 (IL-2R) when tested directly ex-vivo with monoclonal antibodies against the receptor.
(5) The patients were divided into two equal groups according to the degree of perivascular and paratrabecular infiltration: those with minimal (one to three layers of blasts and promyelocytes) and those with marked (four to eight layers of blasts and promyelocytes) infiltration.
(6) Sequential analyses of the serologic reactivity of cells from AMML patients undergoing chemotherapy corresponded with the clinical course of the patient, even though there was little correlation between the percentage of blast cells present and the per cent cytotoxicity with the antisera.
(7) Conversely, the expression in the more differentiated blast cells obtained from 10 of 11 AML patients classified as M1 and M2 were at levels similar to the levels in HL-60 cells.
(8) We concluded that patients with MDS with excess of blasts and blastic transformation may be treated with aggressive chemotherapy with low toxicity and high remission rate, similarly to de novo acute myeloid leukemia.
(9) "Everyone has been blasted by anonymous figures who crushed the economy.
(10) At the second admission, blasts were present in the peripheral blood, and later accounted for 49% of the total leukocyte count.
(11) Lymphocyte blast transformation, serum immunoglobulins, and circulating immune complexes were also evaluated.
(12) In the phase of blast crisis, the bone marrow demonstrated a significant rise of the portion of the G2 cells and of the mitotic index.
(13) Lymphocytes with low floating density lyse NK-sensitive target cells and leukemic B-lymphocytes, increase the lytic activity with respect to blasts of K-562 line under the effect of alpha-interferon.
(14) During tumor growth, a population of T cell blasts appears that may be involved with an immune response against the tumor.
(15) In the high-grade component, the blasts occurred in clusters or sheets, and often possessed plasmacytoid cytoplasm; glandular invasion was a rare event.
(16) The results showed that increasing age of the donors and the presence of anti-CMV antibodies are significantly associated with low proliferative responses of PBMC, whereas the HLA-B8 antigen and female donor sex were found to be associated with high blast cell formation after PWM stimulation.
(17) You can also blast individual eyeballs from their sockets, or – if you're particularly skilful – make their testicles explode like a pair of microwaved eggs.
(18) Fifteen injuries resulted from direct penetration of a vessel and three were concussion or blast injuries.
(19) A2HSGP did indeed inhibit blast transformation in these cell populations.
(20) Late-night hosts blast Trumpcare: 'Needless suffering for low and middle-income people' Read more In the Harvard study, the researchers had 9,000 people in their dataset – enough that they were able to ensure they were really measuring the impact of a lack of health insurance.
Blastema
Definition:
(n.) The structureless, protoplasmic tissue of the embryo; the primitive basis of an organ yet unformed, from which it grows.
Example Sentences:
(1) They are capable of synthesis and accumulation of glycogen and responsible for its transfer to sites of more intense metabolism (growth, bud, blastema).
(2) Blastemas implanted with 2 dorsal root ganglia and simultaneously denervated 14 days after amputation exhibited control levels of cell cycle activity 6 days later, as measured by 3H-thymidine pulse labeling.
(3) A search for specific proteins involved in newt limb regeneration, using monoclonal antibodies against forelimb blastemas, led to the detection of an antigen in the regenerate epithelium.
(4) Between different tumours, heterogeneity in the degree of epithelial differentiation in the blastema was found.
(5) After amputation, limbs of both early and late stages form a regenerative blastema and support lens formation from the outer cornea.
(6) More difficult are clear therapeutic recommendations for the very rare forms of endocrinically active genital tumors which stem from sex cords or which are composed of different components of the complex ovarian blastema.
(7) By 15 days, a dense accumulation of blastema cells is present beneath the apical cap, and these cells are preferentially oriented in a circumferential direction.
(8) Not all cells of the adult newt blastema are randomly distributed and actively progressing through the cell cycle.
(9) Thus, it appears that denervation of medium-bud-stage limb blastemas promotes the lengthening of G1 and premature exiting of cells from the cycle into the G0-1 phase.
(10) Computer-assisted morphometric analysis showed only minor differences between proximal tubular cells from 18-day embryos and tubular cells from 7-day cultures of blastema taken from 11-day embryos.
(11) In the absence of skin, epidermal wound healing failed to occur and blastemas could not develop.
(12) At the contact between the ureter and the mesonephretic blastema, the cells of the primary ureter have special characteristics: existence of an abundant "coat", numerous "villous processes" and a dense network of fibres of collagen.
(13) Serial angiograms and tissue biopsies documented the transition from nodular renal blastema to Wilms' tumor.
(14) After amputation, NvKII mRNA is expressed both in proximal and distal blastemas, although at higher levels distally, indicating that this keratin is regeneration associated.
(15) Since others have shown that denervation at the time of amputation blocks subsequent mitosis in internal stump tissues yet allows normal levels of DNA synthesis for eight days, we conclude that X-irradiation and denervation prevent cell division in potential blastema cells by different mechanisms.
(16) In a study of 71 female foetuses, gonadal blastema was observed at 1.5 cm crown rump length (CRL).
(17) Furthermore, staining with three fucose-binding lectins revealed that the linkage between terminal alpha-fucose residues to the constituent oligosaccharide chains varied between epithelial cells, blastema and stroma.
(18) However, in differentiation phase blastemas, laminin immunoreactivity was concentrated in specific locations.
(19) The fasciculata cells are the direct continuation of the subcapsular blastema.
(20) These results indicate that the limb tissues of the early stage limbs contain non-neural inductive factors at a low level and that after limb amputation and blastema formation the level of these factors becomes high enough to promote lens formation from implanted cornea, even after denervation.