(v. t.) To spot, stain, or bespatter, as with ink.
(v. t.) To impair; to damage; to mar; to soil.
(v. t.) To stain with infamy; to disgrace.
(v. t.) To obliterate, as writing with ink; to cancel; to efface; -- generally with out; as, to blot out a word or a sentence. Often figuratively; as, to blot out offenses.
(v. t.) To obscure; to eclipse; to shadow.
(v. t.) To dry, as writing, with blotting paper.
(v. i.) To take a blot; as, this paper blots easily.
(n.) A spot or stain, as of ink on paper; a blur.
(n.) An obliteration of something written or printed; an erasure.
(n.) A spot on reputation; a stain; a disgrace; a reproach; a blemish.
(n.) An exposure of a single man to be taken up.
(n.) A single man left on a point, exposed to be taken up.
(n.) A weak point; a failing; an exposed point or mark.
Example Sentences:
(1) Western blot analysis of these mitochondria using an antibody against carnitine palmitoyltransferase II purified from beef heart demonstrates a 68-kDa protein, which under ischemic conditions apparently is decreased by 2 kDa.
(2) We have developed a new procedure for the rapid preparation of undegraded total RNA from cultured cells for specific quantitation by dot blotting analysis.
(3) Only the approximately 2.7 kb mRNA species was visualized in Northern blots of total cellular and poly(A+) RNA isolated from cardiac ventricular muscle.
(4) In addition to performing Northern and Western blots for tyrosinase, tyrosine hydroxylase activity (THA) and dopa oxidase activity (DOA) were measured.
(5) After Western blot, 2 of the 5 protein bands of swine-cag (27 and 57 kD) and 3 of the 8 protein bands of human cag (27, 32, and 57 kD) reacted with the anti-Toxoplasma antibody used in the ELISA.
(6) Northern blot analysis with an 18-mer radiolabelled oligonucleotide, derived from an ALP specific cDNA clone, revealed a specific mRNA of about 700-800 nucleotides in HS-24 tumor cells.
(7) We have examined the pattern of bFGF expression during CNS development using protein immunoblot and RNA blot analyses.
(8) Therefore, we conclude this is a bovine DR beta-like pseudogene, BoDR beta I. Exon-containing regions have been used as probes in Southern blot analyses of bovine genomic DNA digested with EcoRI.
(9) Three distinct antigenic regions of bovine somatotropin (bST) were identified on the basis of the ability of a set of monoclonal antibodies to bind to proteolytic fragments and deletion variants of recombinant bST (rbST) in Western blot analyses.
(10) cDNA isolations, RNA, and genomic DNA blots confirm the existence and expression of two genes that produce indistinguishable SOD-4 proteins.
(11) We studied the feasibility of using RNA and DNA from autopsies for Northern and Southern blot analysis.
(12) Analysis of glutamate dehydrogenase (GDH) expression by enzyme assay and immunoblots, as well as Northern and dot blots of poly (A)+ RNA, in the deletion strains indicates that there are two upstream regulatory sequences that control the level of gene expression.
(13) The probe encoding LHCPII hybridizes to RNAs of 9.5 and 6.6 kb on northern blots of total RNA while the 3'-end probe hybridizes only to the 6.6 kb RNA.
(14) Enzyme activities were measured on nitrocellulose blots by using pure enzyme preparations as well as Triton X-100-solubilized membranes.
(15) The results indicated a very good comparability between the dot-blot assay and IF-tests, and this dot-blot method was ascertained as a simple and useful method for the scrub typhus serodiagnosis.
(16) An increase in cytoplasmic PRL mRNA content was evident in all the animals treated with estrogen as revealed with cytoplasmic dot blot analysis.
(17) All these strains produced an enterotoxic principle, antigenically related to cholera coli family of enterotoxins, as detected by latex agglutination and immuno-dot-blot tests.
(18) These alterations were not dependent on the prophage integration prior to curing, and no phage DNA was detected in cured cells by blot hybridisation.
(19) This study shows that the sensitivity and specificity of in situ hybridisation for the detection of EBV genomes in AIDS related lymphomas approaches that of Southern blotting, even when using routinely processed archival, paraffin wax embedded material.
(20) Western blot analysis revealed that the effect of PMA on U-373MG cells shows specificity in that GFA protein levels decline, while those of other major cytoskeletal proteins were unaltered.
Botch
Definition:
(n.) A swelling on the skin; a large ulcerous affection; a boil; an eruptive disease.
(n.) A patch put on, or a part of a garment patched or mended in a clumsy manner.
(n.) Work done in a bungling manner; a clumsy performance; a piece of work, or a place in work, marred in the doing, or not properly finished; a bungle.
(n.) To mark with, or as with, botches.
(n.) To repair; to mend; esp. to patch in a clumsy or imperfect manner, as a garment; -- sometimes with up.
(n.) To put together unsuitably or unskillfully; to express or perform in a bungling manner; to spoil or mar, as by unskillful work.
Example Sentences:
(1) But to treat a mistake as an automatic disqualification for advancement – even as heinous a mistake as presiding over a botched operation that resulted in the killing of an innocent man – could be depriving organisations, and the country, of leaders who have been tested and will not make the same mistake again.
(2) And they should also remember the alternatives to medically assisted dying: botched suicide attempts, death by voluntary starvation and dehydration, pilgrimages to Switzerland and help from one-off amateurs who have the threat of prosecution hanging over them.
(3) What Katrina left behind: New Orleans' uneven recovery and unending divisions Read more Ten years on, resentment still lingers about the failure of the federal levee system during hurricane Katrina, the botched response of the Federal Emergency Management Agency (Fema), and the long and difficult process of accessing billions of dollars in grant money for rebuilding, which for some people is not finished.
(4) Appearing before the Business, Innovation and Skills committee, Richard Cormack of Goldman Sachs and James Robertson, managing director of UBS, were accused of botching the flotation and costing the taxpayers many millions of pounds.
(5) Botched FGM can leave women doubly incontinent and ostracised by their communities.
(6) The Oklahoma prison admitted that the drugs and IV fluid “infiltrated” and “extravasated” into the tissues of Lockett’s groin because of the misplaced catheter, and that is why the execution was prolonged and botched.
(7) A botched job, on its own, narrow terms, AQA's list – launched in the week in which British readers and the national press has been mourning the death of Maya Angelou – is even more ludicrous and ill-conceived when placed in a wider context.
(8) He did so in protest at Foster’s refusal to stand aside temporarily from her post as first minister while a public inquiry was held into a costly botched green energy scheme.
(9) Amid her grief and despair, MacKeown still feels anger at the Goa police for the first, botched autopsy.
(10) Lee insisted in interviews that he had been blinded during a critical instant before the botched landing by a piercing light from outside the aircraft.
(11) – and the botched Fast & Furious gun-running sting, which is a whole different ballgame and beside the point.
(12) He had earlier challenged the constitutionality of another drug in the cocktail, midazolam, which last year was used in the botched execution of Oklahoma inmate Clayton Lockett , who writhed on a gurney for 43 minutes before dying.
(13) They add this appears to be the outcome of a botched late-night drafting process and complete lack of consultation with bloggers, online journalists and social media users, who may now be caught in regulations which trample on grassroots democratic activity and Britain's emerging digital economy.
(14) In June 2012, the month that Butt was sentenced to 15 years in jail, the DSI smashed another major counterfeiting syndicate, this one accused of issuing some 3,000 falsified passports and visas over the five years of its existence, two of them to Iranians convicted of carrying out a series of botched bomb attacks in Bangkok in February 2012, supposedly aimed at Israeli diplomats .
(15) These included a botched phone-in competition to name a new Blue Peter cat and problems with phone-ins for TV shows including Children in Need, Sport Relief, and Comic Relief, and radio programmes hosted by Liz Kershaw, Russell Brand, Claire McDonnell and Jo Whiley.
(16) Risen writes on botched Iranian operation, gets subpoenaed."
(17) Photograph: AP Maya Foa, of anti-death penalty group Reprieve, said: “The state of Arizona had every reason to believe that this procedure would not go smoothly; the experimental execution ‘cocktail’ had only been used once before, and that execution too was terribly botched.
(18) In the document, Rabbani's lawyer tells how his client reported several botched attempts at force feeding.
(19) Midazolam was also used in the botched execution of Clayton Lockett by Oklahoma in April.
(20) A nurse who faces being struck off over a botched Ebola screening at Heathrow airport has said it is “preposterous” that she would have concealed knowledge that Pauline Cafferkey was unwell.