(1) Measles can spread when it reaches a community in the US where groups of people are unvaccinated.” The highly contagious viral respiratory disease is often accompanied by a blotchy rash, fever, runny nose, cough, body aches, watery eyes or pink eye and tiny white spots in the mouth.
(2) The skin lesions, the hallmark of this condition, are distributed in a linear or blotchy pattern and include congenital ichthyosiform erythroderma, systematized atrophoderma mainly involving the hair follicles, and circumscribed alopecia.
(3) These abnormalities in the lung of the Blotchy mouse suggest that the defects of the connective tissue proteins described in skin and aorta also involve the lung.
(4) Static air and saline pressure-volume curves show that lungs of Blotchy mice have decreased elastic recoil and are significantly more compliant than normal.
(5) The hyperkeratoses of the newborn as well as the ensuing atrophoderma predominantly involve the hair follicles and are distributed in a bizarre linear or blotchy pattern.
(6) RDS shows pandysautonomia, including alacrima, orthostatic hypotension, gastrointestinal paresis, and paroxysmal hyperautonomic state, such as hypertension, vomiting crisis, and blotchy erythema.
(7) In this regard, the whitish pigment pattern of skin fragments is compared to the tiny black spots found on anti-FN treated skin fragments and the abundant blotchy spots found on skin cultured alone.
(8) Our studies of liver copper metabolism were conducted in the mottled (blotchy) mouse, an animal model of KHS.
(9) Aortic aneurysms develop in blotchy mice in a consistent fashion, with characteristic gross and histologic changes.
(10) Interpol officers hope that a blotchy and pixelated photo of him may help to trigger a memory somewhere.
(11) Autografts then became pale, took on the appearance of normal skin with the inflammatory changes subsiding, whereas homografts became firm, showed heavy mononuclear cell infiltration, had a blotchy purple appearance due to thrombosis and haemorrhage, developed widespread necrosis and changed into a black hard scab which was eventually shed.
(12) Menkes' disease (classical and mild variant forms) and X linked Ehlers-Danlos syndrome (type IX, X linked cutis laxa) have features in common with one another and with the brindled (Mobr) and blotchy (Moblo) mouse mutants, respectively.
(13) Male normal and blotchy mice 1 to 8 months of age were killed and latex was injected into the left ventricles to facilitate exposure, examination, histologic sampling, and photography of the aorta.
(14) The murine mottled mutants brindled, Mo br, and blotchy, Mo blo, are valuable animal models for the study of mammalian copper metabolism.
(15) It is a blotchy hyperpigmentation of the face which can be a disfiguring cosmetic and emotional problem.
(16) Finally, metallothionein-I mRNA content was not elevated in blotchy kidneys at early developmental stages, before storage of excessive copper.
(17) While metallothionein-I messenger RNA (mRNA) concentrations were elevated in blotchy fibroblasts, the elevations in metallothionein-I mRNA in response to metallothionein inducers (cadmium, copper) were similar in blotchy and control cells.
(18) An animal model is provided by mice hemizygous for mutant alleles, such as the blotchy allele, at the X-linked mottled locus.
(19) These data show a reduced biliary excretion of copper in the blotchy mouse, in the absence of a defect in hepatic copper uptake.
(20) In the blotchy mouse and in cultured skin fibroblasts derived therefrom, we showed that the mutation specifically affects the metabolism of copper and not other trace metals.
Botchy
Definition:
(a.) Marked with botches; full of botches; poorly done.