(1) Integration of pCIS7 into the wild-type (Tcs) B. subtilis chromosome and amplification of the plasmid sequences generated a Tcr phenotype, even though the DNA on pCIS7 was cloned from Tcs B. subtilis KS162 (Ives and Bott, J. Bacteriol.
(2) A factor analysis was used to determine whether induced loudness adaptation (Botte, Canevet, & Scharf, 1982; Scharf, 1983) and adaptation measured by Hood's (1950) classic Simultaneous Dichotic Loudness Balance technique (SDLB) would cluster on the same factors.
(3) Five years ago the school was "crazy and unsafe", said principal Andrew Bott, who was tasked with turning it around.
(4) An intermittent tone in one ear may induce a large decline in the loudness of a continuous tone in the contralateral ear [Botte et al., J. Acoust.
(5) Over the weekend at the Techcrunch Disrupt hackathon in San Francisco, Australian duo Jethro Botts and David Boulton jumped on stage to present Titstare, an app that lets you "stare at tits".
(6) Gove asked Bott how he swiftly reformed the school.
(7) Bott, K. F. (The University of Chicago, Chicago, Ill.), and R. Davidoff-Abelson.
(8) Three roller-bottes were seeded with venous, and another three with arterial derived endothelial cells for each of three "oxygen saturations" 5, 20 and 50% O2 respectively, and incubated for seven days and then counted.
(9) Examination of residual King-Altman patterns for the general modifier model of Botts & Morales [(1953) Trans.
(10) Since its Km for actin is similar to that of tryptic SF1(A2), it may be concluded that changes in the affinity of SF1 for actin induced by trypsin [Botts, J., Muhlrad, A., Takashi, R., & Morales, M. F. (1982) Biochemistry 21, 6903-6905] are not dependent on the presence of the associated alkali light chain.
(11) One of the boldest things Bott did was cut spending on security and funnel the funds into arts.
(12) Keith Bott, who runs Titanic Brewery with his brother Dave, operating eight pubs in Stoke-on-Trent and Staffordshire, said: “To make that extra £1,000 that we now won’t have to pay, we would have had to sell £2,000 worth of beer.
(13) I cannot find mention of Botts, Boulton or Titstare, which would suggest that not only did the organisers allow a breach in process, they have tried to hide the details by removing any reference to the pair.
(14) David Bott, director of innovation programmes at the Technology Strategy Board , which will work with Nesta to develop the prizes, said: "If you set the challenge in the right way, you unlock the creativity of the community rather than limiting it with our own lack of it."
(15) Bott, Thomas L. (University of Wisconsin, Madison), Janet S. Deffner, Elizabeth McCoy, and E. M. Foster.
(16) Bott and Ultsch (1986) observed that the subtilisin BPN' structure is very tolerant of single mutations, and this tolerance may have been necessary for survival of the enzyme during the course of evolution.
(17) Howevever, David Bott, director of innovation programmes at the Technology Strategy Board , has previously told the Guardian he was sceptical that such charging lanes would be practical: "It's scientifically feasible, but it's whether it's scalable and feasible is another matter."
(18) Kinetic analysis of the extended Botts-Morales mechanism describing irreversible enzyme inactivation has demonstrated that analytical expressions describing the time-course of product formation may be derived for a stable modifier by retaining the usual steady-state assumptions regarding the fluxes around ES and EXS provided quasi-equilibrium modifier binding to E and ES is assumed, but for unstable modifiers all of the binding steps must be assumed to be at quasi-equilibrium in the steady-state, except under restrictive circumstances.
(19) It should be looked into in a transparent way,” Bott said.
(20) Analytical expressions describing the time-dependence of product formation have been derived in coefficient form amenable to non-linear regression analysis for two operationally distinct types of reaction mechanism dependent on whether the reaction of the unstable modifier (X) with either or both the free enzyme (E) and enzyme-substrate complex (ES) occurs as a simple bimolecular process, or proceeds through the intermediacy of either or both adsorptive enzyme-modifier (EX) and enzyme-modifier-substrate (EXS) complexes in what may be considered as an extension of the Botts-Morales general modifier mechanism for (stable) reversible enzyme inhibitors and activators.
Bottom
Definition:
(n.) The lowest part of anything; the foot; as, the bottom of a tree or well; the bottom of a hill, a lane, or a page.
(n.) The part of anything which is beneath the contents and supports them, as the part of a chair on which a person sits, the circular base or lower head of a cask or tub, or the plank floor of a ship's hold; the under surface.
(n.) That upon which anything rests or is founded, in a literal or a figurative sense; foundation; groundwork.
(n.) The bed of a body of water, as of a river, lake, sea.
(n.) The fundament; the buttocks.
(n.) An abyss.
(n.) Low land formed by alluvial deposits along a river; low-lying ground; a dale; a valley.
(n.) The part of a ship which is ordinarily under water; hence, the vessel itself; a ship.
(n.) Power of endurance; as, a horse of a good bottom.
(n.) Dregs or grounds; lees; sediment.
(a.) Of or pertaining to the bottom; fundamental; lowest; under; as, bottom rock; the bottom board of a wagon box; bottom prices.
(v. t.) To found or build upon; to fix upon as a support; -- followed by on or upon.
(v. t.) To furnish with a bottom; as, to bottom a chair.
(v. t.) To reach or get to the bottom of.
(v. i.) To rest, as upon an ultimate support; to be based or grounded; -- usually with on or upon.
(v. i.) To reach or impinge against the bottom, so as to impede free action, as when the point of a cog strikes the bottom of a space between two other cogs, or a piston the end of a cylinder.
(n.) A ball or skein of thread; a cocoon.
(v. t.) To wind round something, as in making a ball of thread.
Example Sentences:
(1) In the far east is the arid, depressed country leading down Hell’s Canyon, which bottoms out at the Snake River, which the wolves crossed when they moved from Idaho, and which they now treat more as a crosswalk than a barrier.
(2) It was one of a series of deaths of black men – deaths in custody, deaths where no one ever got to the bottom of what had happened.
(3) The bottom line is that access to abortion is a matter of social justice.
(4) I could walk around more freely than in North Korea, but it was very apparent I was being watched.” The country consistently sits at the bottom of global freedom rankings, in the company of North Korea and Eritrea.
(5) At the bottom is a tiny harbour where cafe Itxas Etxea – bare brick walls and wraparound glass windows – is serving txakoli, the local white wine.
(6) "The results present a remarkably bleak portrait of life in the UK today and the shrinking opportunities faced by the bottom third of UK society," said the head of the project, Professor David Gordon of Bristol University.
(7) In the dance off tomorrow should be Dave and Karen and Mark and Iveta, but it wouldn't surprise me if Fiona and Anton were in the bottom two instead.
(8) With grievous amazement, never self-pitying but sometimes bordering on a sort of numbed wonderment, Levi records the day-to-day personal and social history of the camp, noting not only the fine gradations of his own descent, but the capacity of some prisoners to cut a deal and strike a bargain, while others, destined by their age or character for the gas ovens, follow "the slope down to the bottom, like streams that run down to the sea".
(9) In some cases, a change in the type of bottom resulted in the opposite order of rates for vessels with the same diameter.
(10) 10.34pm BST Rays 2 - Red Sox 8, bottom of the 6th David Ortiz leads off the inning against Chris Archer, still in the game, he grounds into the Maddon shift.
(11) As is frequently the case, the bottom line in preventing and treating intra-abdominal adhesions is appropriate surgical technique.
(12) Companies like Origin and EnergyAustralia are pushing to weaken the target not, as they like to claim, because that would be good for customers, but because a weaker target is better for their bottom line,” Connor said.
(13) You can be very cosy with someone but, at the end of the day, it’s about the bottom line.
(14) The satellite component is not found when digging up from the tube bottom.
(15) The calibrated aperture in the bottom of each well is small enough to retain fluid contents by surface tension during monolayer growth, but also permits fluid to enter the wells when transfer plates are lowered into receptacles containing washing buffer or test sera.
(16) When you are informed that 200 children are missing, you don’t go to dinner until you have got to the bottom of it.
(17) That is the bottom line.” Others described the need for a policy of containing Iran, especially with the lifting of economic sanctions.
(18) In order to study the effects of different glass ionomers on the metabolism of Streptococcus mutans, test slabs of freshly mixed conventional glass ionomer (Fuji), silver glass ionomer (Ketac-Silver), composite (Silux), and 2-week-old Fuji were fitted into the bottom of a test tube.
(19) The plates were viewed directly in an inverted UV microscope or were inspected and photographed bottoms up with a conventional UV microscope mounted with an old-fashioned uncorrected objective (20 X) which, because of its shorter length, permitted proper focussing.
(20) That's why the policies that are desperately needed for the majority to break the grip of a failed economic model would also help make regulated migration work for all: stronger trade unions, a higher minimum wage, a shift from state-subsidised low pay to a living wage, a crash housing investment programme, a halt to cuts in public services, and an end to the outsourced race to the bottom in employment conditions.