(n.) The lowest part of anything; the foot; as, the bottom of a tree or well; the bottom of a hill, a lane, or a page.
(n.) The part of anything which is beneath the contents and supports them, as the part of a chair on which a person sits, the circular base or lower head of a cask or tub, or the plank floor of a ship's hold; the under surface.
(n.) That upon which anything rests or is founded, in a literal or a figurative sense; foundation; groundwork.
(n.) The bed of a body of water, as of a river, lake, sea.
(n.) The fundament; the buttocks.
(n.) An abyss.
(n.) Low land formed by alluvial deposits along a river; low-lying ground; a dale; a valley.
(n.) The part of a ship which is ordinarily under water; hence, the vessel itself; a ship.
(n.) Power of endurance; as, a horse of a good bottom.
(n.) Dregs or grounds; lees; sediment.
(a.) Of or pertaining to the bottom; fundamental; lowest; under; as, bottom rock; the bottom board of a wagon box; bottom prices.
(v. t.) To found or build upon; to fix upon as a support; -- followed by on or upon.
(v. t.) To furnish with a bottom; as, to bottom a chair.
(v. t.) To reach or get to the bottom of.
(v. i.) To rest, as upon an ultimate support; to be based or grounded; -- usually with on or upon.
(v. i.) To reach or impinge against the bottom, so as to impede free action, as when the point of a cog strikes the bottom of a space between two other cogs, or a piston the end of a cylinder.
(n.) A ball or skein of thread; a cocoon.
(v. t.) To wind round something, as in making a ball of thread.
Example Sentences:
(1) In the far east is the arid, depressed country leading down Hell’s Canyon, which bottoms out at the Snake River, which the wolves crossed when they moved from Idaho, and which they now treat more as a crosswalk than a barrier.
(2) It was one of a series of deaths of black men – deaths in custody, deaths where no one ever got to the bottom of what had happened.
(3) The bottom line is that access to abortion is a matter of social justice.
(4) I could walk around more freely than in North Korea, but it was very apparent I was being watched.” The country consistently sits at the bottom of global freedom rankings, in the company of North Korea and Eritrea.
(5) At the bottom is a tiny harbour where cafe Itxas Etxea – bare brick walls and wraparound glass windows – is serving txakoli, the local white wine.
(6) "The results present a remarkably bleak portrait of life in the UK today and the shrinking opportunities faced by the bottom third of UK society," said the head of the project, Professor David Gordon of Bristol University.
(7) In the dance off tomorrow should be Dave and Karen and Mark and Iveta, but it wouldn't surprise me if Fiona and Anton were in the bottom two instead.
(8) With grievous amazement, never self-pitying but sometimes bordering on a sort of numbed wonderment, Levi records the day-to-day personal and social history of the camp, noting not only the fine gradations of his own descent, but the capacity of some prisoners to cut a deal and strike a bargain, while others, destined by their age or character for the gas ovens, follow "the slope down to the bottom, like streams that run down to the sea".
(9) In some cases, a change in the type of bottom resulted in the opposite order of rates for vessels with the same diameter.
(10) 10.34pm BST Rays 2 - Red Sox 8, bottom of the 6th David Ortiz leads off the inning against Chris Archer, still in the game, he grounds into the Maddon shift.
(11) As is frequently the case, the bottom line in preventing and treating intra-abdominal adhesions is appropriate surgical technique.
(12) Companies like Origin and EnergyAustralia are pushing to weaken the target not, as they like to claim, because that would be good for customers, but because a weaker target is better for their bottom line,” Connor said.
(13) You can be very cosy with someone but, at the end of the day, it’s about the bottom line.
(14) The satellite component is not found when digging up from the tube bottom.
(15) The calibrated aperture in the bottom of each well is small enough to retain fluid contents by surface tension during monolayer growth, but also permits fluid to enter the wells when transfer plates are lowered into receptacles containing washing buffer or test sera.
(16) When you are informed that 200 children are missing, you don’t go to dinner until you have got to the bottom of it.
(17) That is the bottom line.” Others described the need for a policy of containing Iran, especially with the lifting of economic sanctions.
(18) In order to study the effects of different glass ionomers on the metabolism of Streptococcus mutans, test slabs of freshly mixed conventional glass ionomer (Fuji), silver glass ionomer (Ketac-Silver), composite (Silux), and 2-week-old Fuji were fitted into the bottom of a test tube.
(19) The plates were viewed directly in an inverted UV microscope or were inspected and photographed bottoms up with a conventional UV microscope mounted with an old-fashioned uncorrected objective (20 X) which, because of its shorter length, permitted proper focussing.
(20) That's why the policies that are desperately needed for the majority to break the grip of a failed economic model would also help make regulated migration work for all: stronger trade unions, a higher minimum wage, a shift from state-subsidised low pay to a living wage, a crash housing investment programme, a halt to cuts in public services, and an end to the outsourced race to the bottom in employment conditions.
Castor
Definition:
(n.) A genus of rodents, including the beaver. See Beaver.
(n.) Castoreum. See Castoreum.
(n.) A hat, esp. one made of beaver fur; a beaver.
(n.) A heavy quality of broadcloth for overcoats.
(n.) See Caster, a small wheel.
(n.) the northernmost of the two bright stars in the constellation Gemini, the other being Pollux.
(n.) Alt. of Castorite
Example Sentences:
(1) However, this inhibition was not found in rats treated with castor oil for 3 d. Moreover, 5-HT concentration in the midbrain significantly decreased in rats that acquired the adaptability for the occurrence of diarrhea.
(2) The IgE potentiating component in castor bean was found to enhance IgE responses to other antigens such as ovalbumin and when 0.8 microgram of an unheated castor bean extract was administered together with an optimal dose of ovalbumin, there was a substantial increase in ovalbumin-specific IgE but not IgG in all animals.
(3) The time-course of castor oil-induced diarrhea in fasted rats was quantified by weighing stools every 15 minutes for 8 hours after the challenge and then after 24 hours.
(4) We compared the antidiarrheal effects of CGS 9343B to other prototype antidiarrheal agents including morphine, loperamide and chlorpromazine in the castor oil-induced model of secretory diarrhea in mice.
(5) The nucleotide sequence of the castor clone pRCD1 revealed an open reading frame of 1.2 kilobases encoding a 396-amino acid protein of 45 kDa.
(6) Castor bean allergy seems to be a good model in the testing of human reaginic hypersensitivity.
(7) The plasma membrane components of five human B-cell lines and three human T-cell lines were separated by dodecyl sulfate polyacrylamide gel electrophoresis, incubated with the radioactive labeled lectins from lentil, castor bean, wheat germ, Phaseolus bean, peanut, gorse and the Roman snail and the molecular weights of the binding sites determined.
(8) Conformation and conformational transitions of phytohemagglutinins (lectins) from Arachis hypogaea (peanut), Lens culinaris (lentil), Glycine max (soybean), and Ricinus communis (castor bean) were studied by the circular dichroism probe.
(9) Initiation of breast-feeding within 4-6 hours was noted only in 8.03% of mothers whereas 53.07% of mothers and 9.72% of mothers started sugar water and castor oil as prelacteal feedings respectively.
(10) The following 125I-lectins were used: Concanavalin-A (specific for glucose and mannose), wheat germ agglutinin (specific for N-acetylglucosamine), castor bean agglutinin (specific for galactose), Wistaria floribunda agglutinin (specific for N-acetylgalactosamine), and soybean agglutinin (specific for N-acetyl-galactosamine).
(11) Although the highly toxic nature of castor bean (Ricinus communis) is well recognized, reports of human toxicity in the English medical literature are scarce.
(12) An orally applicable pulsatile drug delivery system in dry-coated tablet form was prepared using diltiazem hydrochloride as the model drug, and a polyvinyl chloride-hydrogenated castor oil-polyethyleneglycol mixture as the outer shell of the tablet.
(13) The IgE response to castor bean (Ricinus communis) was studied in 96 castor bean-allergic patients from Marseilles, France.
(14) Strains of types a, d, f, and g agglutinated within 2 h. Strains of a, d, and f were also agglutinated in 2 h by the castor bean lectin RCA.
(15) Regional changes in concentrations of histamine (HA), serotonin (5-HT) and 5-hydroxyindoleacetic acid (5-HIAA) in the rat brain were investigated after diarrhea induced by castor oil.
(16) The effects of oil components in the formulated vehicle on the permeation of diclofenac across the skin were in the following order: squalane greater than or equal to squalene greater than liquid paraffin greater than middle chain triglyceride greater than olive oil greater than castor oil.
(17) Pretreatment of intact castor bean endosperm tissue with tunicamycin partially inhibits the cotranslational core glycosylation step and results in the accumulation of a single sized unglycosylated precursor polypeptide of relative molecular mass 59 000.
(18) In solvent-pretreated rats, diarrhea was always observed within 90 min after castor oil, reflecting a state of hyperpropulsive activity of the gut, but never (up to 8 h) after paraffin oil, reflecting normal intestinal propulsion (which amounted to an average distance of 91% of the total length of the small intestine in 90 min).
(19) Studies have been made on the peroxidase activity of metmyoglobins in animals from various ecological groups--the horse Equus caballus, cattle Bos taurus, beaver Castor fiber, otter Lutra lutra, mink Mustela vison and dog Canis familiaris.
(20) Healthy subjects and conventional as well as germ-free rats also excrete these substances after ingestion of castor oil.