(n.) The external or limiting line, either real or imaginary, of any object or space; that which limits or restrains, or within which something is limited or restrained; limit; confine; extent; boundary.
(v. t.) To limit; to terminate; to fix the furthest point of extension of; -- said of natural or of moral objects; to lie along, or form, a boundary of; to inclose; to circumscribe; to restrain; to confine.
(v. t.) To name the boundaries of; as, to bound France.
(v. i.) To move with a sudden spring or leap, or with a succession of springs or leaps; as the beast bounded from his den; the herd bounded across the plain.
(v. i.) To rebound, as an elastic ball.
(v. t.) To make to bound or leap; as, to bound a horse.
(v. t.) To cause to rebound; to throw so that it will rebound; as, to bound a ball on the floor.
(n.) A leap; an elastic spring; a jump.
(n.) Rebound; as, the bound of a ball.
(n.) Spring from one foot to the other.
() imp. & p. p. of Bind.
(p. p. & a.) Restrained by a hand, rope, chain, fetters, or the like.
(p. p. & a.) Inclosed in a binding or cover; as, a bound volume.
(p. p. & a.) Under legal or moral restraint or obligation.
(p. p. & a.) Constrained or compelled; destined; certain; -- followed by the infinitive; as, he is bound to succeed; he is bound to fail.
(p. p. & a.) Resolved; as, I am bound to do it.
(p. p. & a.) Constipated; costive.
(v.) Ready or intending to go; on the way toward; going; -- with to or for, or with an adverb of motion; as, a ship is bound to Cadiz, or for Cadiz.
Example Sentences:
(1) These studies led to the following conclusions: (a) all the prominent NHP which remain bound to DNA are also present in somewhat similar proportions in the saline-EDTA, Tris, and 0.35 M NaCl washes of nuclei; (b) a protein comigrating with actin is prominent in the first saline-EDTA wash of nuclei, but present as only a minor band in the subsequent washes and on washed chromatin; (c) the presence of nuclear matrix proteins in all the nuclear washes and cytosol indicates that these proteins are distributed throughout the cell; (d) a histone-binding protein (J2) analogous to the HMG1 protein of K. V. Shooter, G.H.
(2) The results demonstrated that K2PtCl4 was bound to a greater degree than CDDP in this system with 3-5 and 1-2 platinum atoms respectively, bound per transferrin molecule.
(3) Extensive studies during recent years have shown that the interaction between hormone and membrane-bound receptor can affect the receptor characteristics in at least two ways.
(4) These results are discussed in relation to the possible existence of enzyme-bound intermediates of nitrogen fixation.
(5) In the second approach, attachment sites of DTPA groups were directed away from the active region of the molecule by having fragment E1,2 bound in complex, with its active sites protected during the derivatization.
(6) For similar inotropic responses, normo- and hyperkalaemic dogs had similar levels of (Na+, K+)-ATPase inhibition and microsomal-bound digoxin.
(7) The penicillin-resistant Enterococcus hirae R40 has a typical profile of membrane-bound penicillin-binding proteins (PBPs) except that the 71 kDa PBP5 of low penicillin affinity represents about 50% of all the PBPs present.
(8) Electron spin resonance studies indicate the formation of two vanadyl complexes that are 1:1 in vanadyl and deferoxamine, but have two or three bound hydroxamate groups.
(9) Treatment of the bound F1-ATPase with 4-chloro-7-nitrobenzofurazan prevented complete release of the enzyme by ATP.
(10) Only estrogenic hormones are bound with high affinity.
(11) Plasma for beta-endorphin assay was preincubated with sepharose-bound anti-beta-lipotropin to remove beta-lipotropin that cross-reacted with the beta-endorphin RIA.
(12) I think part of it is you can either go places where that's bound to happen.
(13) Freshly isolated sarcoplasmic reticulum vesicles contain 0.05 mol of tightly bound ADP and 0.03 mol of tightly bound ATP per mol of Ca2+, Mg2+-ATPase (ATP phosphohydrolase, EC 3.6.1.3).
(14) Agarose-albumin beads may be useful for removing protein-bound substances from the blood of patients with liver failure, intoxication with protein-bound drugs, or specific metabolic deficits.
(15) Immunoabsorption studies showed that these four antibodies bound to the same molecule as OKT9, an antibody to the transferrin receptor.
(16) We investigated this suppression quantitatively, using a chemical assay for cell-bound and dissolved capsular polysaccharide.
(17) Only IgG2a and IgG2b myeloma proteins bound readily to IC-21 Fc-receptors, the former in nonaggregated as well as aggregated form, the latter only as aggregated complexes.
(18) When antibodies were bound to cell-surface DPP IV at 4 degrees C, the immune complex remained stable for more than 1 h after rewarming to 37 degrees C, despite ongoing metabolic and membrane transport processes.
(19) Plasmids containing the inverted repeat alone bound ER, though less efficiently than did plasmids containing the entire sequence.
(20) Inhibition of fast axonal transport by an antibody specific for kinesin provides direct evidence that kinesin is involved in the translocation of membrane-bounded organelles in axons.
Free
Definition:
(superl.) Exempt from subjection to the will of others; not under restraint, control, or compulsion; able to follow one's own impulses, desires, or inclinations; determining one's own course of action; not dependent; at liberty.
(superl.) Not under an arbitrary or despotic government; subject only to fixed laws regularly and fairly administered, and defended by them from encroachments upon natural or acquired rights; enjoying political liberty.
(superl.) Liberated, by arriving at a certain age, from the control of parents, guardian, or master.
(superl.) Not confined or imprisoned; released from arrest; liberated; at liberty to go.
(superl.) Not subjected to the laws of physical necessity; capable of voluntary activity; endowed with moral liberty; -- said of the will.
(superl.) Clear of offense or crime; guiltless; innocent.
(superl.) Unconstrained by timidity or distrust; unreserved; ingenuous; frank; familiar; communicative.
(superl.) Unrestrained; immoderate; lavish; licentious; -- used in a bad sense.
(superl.) Not close or parsimonious; liberal; open-handed; lavish; as, free with his money.
(superl.) Exempt; clear; released; liberated; not encumbered or troubled with; as, free from pain; free from a burden; -- followed by from, or, rarely, by of.
(superl.) Characteristic of one acting without restraint; charming; easy.
(superl.) Ready; eager; acting without spurring or whipping; spirited; as, a free horse.
(superl.) Invested with a particular freedom or franchise; enjoying certain immunities or privileges; admitted to special rights; -- followed by of.
(superl.) Thrown open, or made accessible, to all; to be enjoyed without limitations; unrestricted; not obstructed, engrossed, or appropriated; open; -- said of a thing to be possessed or enjoyed; as, a free school.
(superl.) Not gained by importunity or purchase; gratuitous; spontaneous; as, free admission; a free gift.
(superl.) Not arbitrary or despotic; assuring liberty; defending individual rights against encroachment by any person or class; instituted by a free people; -- said of a government, institutions, etc.
(superl.) Certain or honorable; the opposite of base; as, free service; free socage.
(superl.) Privileged or individual; the opposite of common; as, a free fishery; a free warren.
(superl.) Not united or combined with anything else; separated; dissevered; unattached; at liberty to escape; as, free carbonic acid gas; free cells.
(adv.) Freely; willingly.
(adv.) Without charge; as, children admitted free.
(a.) To make free; to set at liberty; to rid of that which confines, limits, embarrasses, oppresses, etc.; to release; to disengage; to clear; -- followed by from, and sometimes by off; as, to free a captive or a slave; to be freed of these inconveniences.
(a.) To remove, as something that confines or bars; to relieve from the constraint of.
(a.) To frank.
Example Sentences:
(1) Cancer patients showed abnormally high plasma free tryptophan levels.
(2) In conclusion, the efficacy of free tissue transfer in the treatment of osteomyelitis is geared mainly at enabling the surgeon to perform a wide radical debridement of infected and nonviable soft tissue and bone.
(3) The authors have presented in two previous articles the graphic solutions resembling Tscherning ellipses, for spherical as well as for aspherical ophthalmic lenses free of astigmatism or power error.
(4) The hypothesis that proteins are critical targets in free radical mediated cytolysis was tested using U937 mononuclear phagocytes as targets and iron together with hydrogen peroxide to generate radicals.
(5) With NaCl as the major constituent of the bathing solution (potassium-free pipette and external solutions) the reversal potential (Er) of the noradrenaline-evoked current was about 0 mV.
(6) In cardiac tissue the adenylate system is not a good indicator of the energy state of the mitochondrion, even when the concentrations of AMP and free cytosolic ADP are calculated from the adenylate kinase and creatine kinase equilibria.
(7) The promoters of the adenovirus 2 major late gene, the mouse beta-globin gene, the mouse immunoglobulin VH gene and the LTR of the human T-lymphotropic retrovirus type I were tested for their transcription activities in cell-free extracts of four cell lines; HeLa, CESS (Epstein-Barr virus-transformed human B cell line), MT-1 (HTLV-I-infected human T cell line without viral protein synthesis), and MT-2 (HTLV-I-infected human T cell line producing viral proteins).
(8) This frees the student to experience the excitement and challenge of learning and the joy of helping people.
(9) The role of O2 free radicals in the reduction of sarcolemmal Na+-K+-ATPase, which occurs during reperfusion of ischemic heart, was examined in isolated guinea pig heart using exogenous scavengers of O2 radicals and an inhibitor of xanthine oxidase.
(10) This sling was constructed bu freeing the insertion of the pubococcygeus and the ileococcygeus muscles from the coccyx.
(11) In Ca free-solution phenylephrine inhibited the response to CaCl2.
(12) The actuarial 5-year disease-free survival rates were 83% (group 1), 83% (group 2), and 100% (group 3).
(13) Their effects on various lipid fractions, viz., triglycerides (TG), phospholipids, free cholesterol, and esterified cholesterol, were studied in liver, plasma, gonads, and muscle.
(14) These deficiencies in the data compromise HIV surveillance based on diagnostic testing, and supplementary bias-free data are needed.
(15) The authors conclude that H. pylori alone causes little or no effect on an intact gastric mucosa in the rat, that either intact organisms or bacteria-free filtrates cause similar prolongation and delayed healing of pre-existing ulcers with active chronic inflammation, and that the presence of predisposing factors leading to disruption of gastric mucosal integrity may be required for the H. pylori enhancement of inflammation and tissue damage in the stomach.
(16) Only those derivatives with a free amino group and net positive charge in the side chain were effective.
(17) Under milder trypsin digestion conditions three resistant fragments were produced from the free protein.
(18) "This was very strategic and it was in line of the ideology of the Bush administration which has been to put in place a free market and conservative agenda."
(19) To determine the influence of cetylpyridinium chloride (CPC) adsorption on the wettability and elemental surface composition of human enamel, with and without adsorbed salivary constituents, surface-free energies and elemental compositions were determined.
(20) By growing purified human cytotrophoblasts under serum-free conditions and manipulating the culture surface, we were able to disassociate morphologic from biochemical differentiation.