(n.) A brindled color; also, that which is brindled.
(a.) Brindled.
Example Sentences:
(1) The brindled mottled mutant mouse, a model of Menkes' disease, has alterations in copper homeostasis which cause, among other sequelae, neuronal degeneration in selected areas of brain.
(2) David Brindle is the Guardian’s public services editor Read more • New series: careers in public services • Why there won’t be mass redundancies in the public sector after the election This article is part of our series on careers in public services .
(3) Neuropathological and enzyme-histochemical studies were performed on brindled mouse hemizygotes (BMs) and normal littermates at the age of 2 days, 7 days, 11 days and 14 days, together with an investigation of their tissue copper levels.
(4) During early development normal and brindled mouse brain use 3-hydroxy-butyrate preferentially to glucose as a source for biosynthetic carbon units.
(5) The most extensively investigated mutants are the mottled mice, in particular brindled mice, which have a mutation analogous to that of Menkes' disease.
(6) Irrespective of how the low levels of the approximately 48-kDa protein may be related to the basic defect in the brindled mice, the data are consistent with an important role for the approximately 48-kDa protein in intracellular copper metabolism.
(7) Brindled mice, which have a genetic defect that affects copper distribution, were compared to their normal brothers.
(8) These results suggest that fetal brain abnormalities caused by Trien-2HCl may be due in part to induction of copper deficiency, which is almost equivalent to that in brindled mutant mouse.
(9) Decreased copper binding and approximately 48-kDa protein were not simply secondary to the abnormal hepatic and renal copper levels that are found in the brindled mice since although their liver copper levels are low, their kidney copper levels are high.
(10) Copper (6 ppm) was administered to pregnant heterozygous brindled and normal mice from 13 to 18 days gestation.
(11) Brindled mice from dams on the -Cu treatment were smaller and had lower packed cell volumes than brindled mice from dams on the +Cu treatment.
(12) Most of the copper in the cytosol of these fibroblasts is bound to metallothionein (MT), which is elevated in Menkes or brindled mouse fibroblasts.
(13) Proteolytically generated fragments of the microfilament anchoring protein brain spectrin were found to accumulate in brindled mouse brain.
(14) At the table David Brindle (Chair) Public services editor, the Guardian Sharon Allen Chief executive, Skills for Care Pete Calveley Chief executive, Barchester Healthcare Michelle Dudderidge Director, Hand in Hands Shaks Ghosh Chief executive, Clore Social Leadership Programme Patrick Vernon Project coordinator, Health Partnership Project, National Housing Federation Martin Green Chief executive, Care England Ray James President, Association of Directors of Adult Social Services in England Des Kelly Executive director, National Care Forum John Kennedy Director of care services, Joseph Rowntree Foundation Neil Matthewman Chief executive, Community Integrated Care John Ransford Non-executive director, HC-One Jon Glasby Professor of health and social care, University of Birmingham Bridget Warr Chief executive, UK Home Care Association There was a recognition from participants that there were some great leaders in social care – but that there was room for improvement, too.
(15) These data show that female brindled mice have neurochemical abnormalities similar to (if less severe than) the male hemizygotes, that these abnormalities are regionally specific, are most apparent prior to 30 days of age, and are linked to behavioral deficits.
(16) Histochemical examinations showed no significant differences in the stainability, morphology and distribution of MAO positive neurons in the brain between normal and brindled mice at the same age.
(17) Copper accumulation by normal fibroblasts containing excess MT was examined to determine if the excess copper accumulation phenotype was secondary to excess MT or associated with the primary defect in fibroblasts from the brindled mice.
(18) Nucleotide levels were low in spleens from brindled mice.
(19) Deficits in oxidative and acetylcholine metabolism occur in the developing brindled mouse, a genetic mutant with a defect in copper homeostasis.
(20) In order to investigate the levels of cytochrome oxidase activity in neuronal mitochondria in the brain of the brindled mouse hemizygote (BM), the cerebella and brain stems from 12 pairs of brindled and normal littermates aged 13-16 days were examined.
Dapple
Definition:
(n.) One of the spots on a dappled animal.
(a.) Alt. of Dappled
(v. t.) To variegate with spots; to spot.
Example Sentences:
(1) But Kiki Bertens, a smiling, 23-year-old Dutch qualifier who looked pleased just to be here, made a decent fist of her impossible assignment in dappled light on Arthur Ashe and pushed Serena Williams at least to the lower slopes of anxiety on day three of the 2015 US Open.
(2) In addition, all affected members show a characteristic pattern of cutaneous hyperpigmentation, which resembles macular amyloidosis around the neck and waist, but which confers a dappled appearance to the axillae, popliteal fossae, thighs, buttocks, and lower aspect of the abdomen.
(3) Drinking water in dappled forest shade, Boban points to wild asparagus growing by the roadside.
(4) Unfortunately this data is about as much use in predicting the future course of the property market as sun-dappled photos of the summer of 1914.
(5) From the drifts of waxy, geometric paper leaves on the floor, to the dappled lighting; from the wonky litter bin, to the library table as the room's centrepiece; Boyce's room is both impressive and affecting.
(6) These findings are interpreted as obvious gene dosis effects of the incompletely dominant merle gene which is used to produce a characteric harlequin dappling in many breeds of dogs.
(7) After creating the Reading striker’s opener, Carney headed England’s late second in front of a capacity 13,000-plus crowd at a sun-dappled Moncton Stadium.
(8) It's 6.30pm and I'm on the sofa, watching an overgrown blue woolly person with a red security blanket and a bell in his foot, who is squeaking and jingling through a sun-dappled wood in the company of a large, excitable dolly - her hair stands on end when she's especially thrilled - who says, 'Ooh!
(9) As for Serena’s great rival, Sharapova, she was seen off by Kerber in a rollicking fourth-round match on a sun-dappled, cabriolet Centre Court: 7-6, 4-6, 6-4.
(10) The perfect summer lunch, for me at least, will involve a table outdoors, but in dappled shade, a group of people who enjoy eating and drinking, and some seasonal food.
(11) Taiyo, but also to dapple fruit symptoms on peach cv.
(12) Leave time for a meal in the grounds at the idyllic Lodi restaurant, where you can loll in a private gypsy wagon overlooking a sun-dappled courtyard, sip cocktails and work your way through the delicious Mediterranean menu.
(13) Probe HSV-1 detected all the members of HSV group, such as HSV-hop, HSV-grapevine, HSV-cucumber, HSV-citrus and a viroid-like RNA isolated from plum trees affected by plum dapple fruit disease.
(14) Her opening week at the helm ended with a rousing welcome from the party faithful at the nationalists' spring conference on a sun-dappled racecourse in west Wales.
(15) On a computer screen, a bald, muddy seam on the woodland floor is being sown over with green, and the sunny dapple is being added (filming was completed in October 2006, after six months of lightning strikes, flash floods and oak blight).
(16) Chord lengths of air spaces from cranial and caudal lobes of lungs were acquired using a Dapple Systems image analyzer, and a two-population frequency distribution was generated for analysis with an IBM PC.
(17) Dappled apple trees and "perfect" lives riddled with curtain-twitching darknesses, great social humour, heartache, industrial-strength bitchiness and, at their best, plotlines that somehow managed to marry Twin Peaks to The Simpsons , and Marcia Cross as the ever-magnificent Bree.
(18) We have studied the detection of apple scar skin, dapple apple, and pear rusty skin viroids in nucleic acid extracts of infected pome fruit tissues by reverse transcription-polymerase chain reaction (RT-PCR) with viroid cDNA-specific primers.
(19) Trees (in fact, the pillars that support the gallery ceiling) loom, their geometric aluminium leaves dappling the light that is cast over the space.
(20) Even the actress Carol White's hair seems to mirror her character's inexorable pitch into poverty, first a gleaming golden halo as she promenades with her fiance Reg in a dappled park, then the neat bob of a housewife and mother, initially flourishing in a posh maisonette with double glazing, then struggling with vermin and bailiffs in a series of increasingly overcrowded and dingy abodes following her husband's sudden unemployment.