(v. t.) Made infirm or weak, by disease, age, or hardships.
(v. t.) Subdued; humbled; contrite.
(v. t.) Subjugated; trained for use, as a horse.
(v. t.) Crushed and ruined as by something that destroys hope; blighted.
(v. t.) Not carried into effect; not adhered to; violated; as, a broken promise, vow, or contract; a broken law.
(v. t.) Ruined financially; incapable of redeeming promises made, or of paying debts incurred; as, a broken bank; a broken tradesman.
(v. t.) Imperfectly spoken, as by a foreigner; as, broken English; imperfectly spoken on account of emotion; as, to say a few broken words at parting.
Example Sentences:
(1) Results suggest that Cd-MT is reabsorbed and broken down by kidney tubule cells in a physiological manner with possible subsequent release of the toxic cadmium ion.
(2) The starting point is the idea that the current system, because it works against biodiversity but fails to increase productivity, is broken.
(3) Again, the boys in care that he abused now speak to us as broken adults.
(4) I think they want to set an example … I don't see anyone who has broken the law."
(5) Records were broken on seats lost and swings suffered.
(6) Slager, 33, was a patrolman first class for the North Charleston police department when he fatally shot Scott, 50, following a struggle that led from a traffic stop when the officer noticed that one of Scott’s car tail lights was broken.
(7) The organizers of the protest march he participated in said the man had fallen ill before any rioting had broken out.
(8) In June 2012 we got our first elected president, and, in his first year in office, the state's monopoly on violence was broken.
(9) Ings twisted the knee during his first training session with Klopp in charge and tests have shown the former Burnley forward ruptured an anterior cruciate ligament, meaning that a player who has just broken into England’s senior team will be out for a minimum of six months.
(10) Regardless of cyst localization, lowest diagnostic sensitivity was observed in patients whose cysts were intact and of the hyaline type, whereas recently broken cysts were associated with the most consistently detectable immune response.
(11) The Broken King by Philip Womack Photograph: Troika Books The Sword in the Stone begins with Wart on a "quest" to find a tutor.
(12) Don was racing the Dodge through the Bonneville Salt Flats , where Gary Gabelich had just (on 23 October) broken the land-speed record.
(13) The time course for these events suggested that the genetic code for synthesis of thymidine kinase can be expressed before "cores" are broken down, but the DNA-polymerase can be synthesized only after liberation of the viral DNA.
(14) Chemical analyses of the radioactive species in the incubation medium showed that a considerable portion of the radiolabeled sugar nucleotide had broken down to cytidine, phosphoric acid, and sialic acid.
(15) She also said that US embassy officials and doctors – who had been blocked from seeing Chen – met him on Friday.said that They said Chen had three broken bones from his escape, and his foot was in a cast.
(16) The size of the broken stone fragments was less than 2 mm in 24 cases (68.5%) and 2 to 5 mm in 10 cases (28.6%), which indicated that the procedure was very effective.
(17) Mohammed Salama, 23, an Al Ahly ultra whose leg was broken in the stadium riot, said it became clear at half-time in the match between the two historical foes that trouble was brewing.
(18) "For so long, management kept us down; they've broken us and bullied us," he said.
(19) Patrick Vieira, captain and on-pitch embodiment of Wenger’s reign, won the trophy with the last kick of his career at the club in the season when the Arsenal-United axis was finally broken by Chelsea at the top of the Premier League.
(20) Trierweiler has broken a fundamental principle of French political life, an unwritten law inherited from the Ancien Régime and perpetuated by France's revolutionary nomenklatura, that the private life – and by that I mean sex life – of a public figure must remain inviolable.
Fragment
Definition:
(v. t.) A part broken off; a small, detached portion; an imperfect part; as, a fragment of an ancient writing.
Example Sentences:
(1) The nucleotide sequence of a 2.2-kb DNA fragment which contains the complete RAD7 gene was determined.
(2) In the second approach, attachment sites of DTPA groups were directed away from the active region of the molecule by having fragment E1,2 bound in complex, with its active sites protected during the derivatization.
(3) The Fc fragment of this protein reacted with and was solubilized by the staphylococcal A protein which also precipitated the intact immunoglobulin.
(4) In order to determine the extent of this similarity, I have developed a panel of probes for many of the Pacl restriction fragments and have shown that most of the Pacl and Notl fragments found in MBa are also present in MBb.
(5) Under milder trypsin digestion conditions three resistant fragments were produced from the free protein.
(6) Five of them had a fast-moving Eco RI fragment 5.6 kb long that hybridized with zeta-specific probe but not with alpha-specific probe.
(7) Comparative data for the fragments from RNAs 1, 2, and 3 show that they have nearly the same sequence as the RNA 4 fragment.
(8) A sperm whale myoglobin gene containing multiple unique restriction sites has been constructed in pUC 18 by sequential assembly of chemically synthesized oligonucleotide fragments.
(9) Urine specimens from patient REE also contained a light chain fragment that lacked the first (amino-terminal) 85 residues of the native light chain but otherwise was identical in sequence to the light chain REE.
(10) Northern hybridization analysis of R. toruloides RNA with a restriction fragment encoding part of the PAL gene indicates that PAL mRNA is 2.5 kilobases in length.
(11) The method of sonicating L3 and Mf fragment antigens used in this study is simple, and its results are easy to observe.
(12) Benzyloxycarbonylarginine p-nitrophenyl ester and other activated esters of N-a-sustituted arginine salts may be useful reagents for introduction of trypsin-labile protecting groups into peptide fragments for purpose of polypeptide semi-synthesis.
(13) The 6.6-kb DNA Bam HI fragment containing the resistance gene was cloned with the plasmid vector pIJ699.
(14) It was found that these Hageman factor fragments promoted rapid proteolysis of one-chain factor VII to a more active two-chain form.
(15) Restriction fragment length polymorphisms (RFLPs) were studied in a large Algerian family which includes 6 haemophiliacs and a previously described case of female haemophilia A.
(16) A 2.7-kilobase DNA fragment carrying the entire exotoxin A (ETA) structural gene was divided into three nonoverlapping probes.
(17) A 6.4 kilobase C4B-5'-specific Taq I fragment usually provided a reliable guide to the presence of a C4A deletion but unusually in one instance this fragment was found to be a marker of a functioning C4A gene.
(18) The method involves the use of a monoclonal antibody fragment mixture that binds to platelets.
(19) Three distinct antigenic regions of bovine somatotropin (bST) were identified on the basis of the ability of a set of monoclonal antibodies to bind to proteolytic fragments and deletion variants of recombinant bST (rbST) in Western blot analyses.
(20) The coding sequence for Spirulina platensis acetohydroxy acid synthase (AHAS, EC 4.1.3.18) is shown to be contained within a 4.2 Kb ClaI fragment (ilvX) that has been cloned from a recombinant lambda library.