(v. t.) Made infirm or weak, by disease, age, or hardships.
(v. t.) Subdued; humbled; contrite.
(v. t.) Subjugated; trained for use, as a horse.
(v. t.) Crushed and ruined as by something that destroys hope; blighted.
(v. t.) Not carried into effect; not adhered to; violated; as, a broken promise, vow, or contract; a broken law.
(v. t.) Ruined financially; incapable of redeeming promises made, or of paying debts incurred; as, a broken bank; a broken tradesman.
(v. t.) Imperfectly spoken, as by a foreigner; as, broken English; imperfectly spoken on account of emotion; as, to say a few broken words at parting.
Example Sentences:
(1) Results suggest that Cd-MT is reabsorbed and broken down by kidney tubule cells in a physiological manner with possible subsequent release of the toxic cadmium ion.
(2) The starting point is the idea that the current system, because it works against biodiversity but fails to increase productivity, is broken.
(3) Again, the boys in care that he abused now speak to us as broken adults.
(4) I think they want to set an example … I don't see anyone who has broken the law."
(5) Records were broken on seats lost and swings suffered.
(6) Slager, 33, was a patrolman first class for the North Charleston police department when he fatally shot Scott, 50, following a struggle that led from a traffic stop when the officer noticed that one of Scott’s car tail lights was broken.
(7) The organizers of the protest march he participated in said the man had fallen ill before any rioting had broken out.
(8) In June 2012 we got our first elected president, and, in his first year in office, the state's monopoly on violence was broken.
(9) Ings twisted the knee during his first training session with Klopp in charge and tests have shown the former Burnley forward ruptured an anterior cruciate ligament, meaning that a player who has just broken into England’s senior team will be out for a minimum of six months.
(10) Regardless of cyst localization, lowest diagnostic sensitivity was observed in patients whose cysts were intact and of the hyaline type, whereas recently broken cysts were associated with the most consistently detectable immune response.
(11) The Broken King by Philip Womack Photograph: Troika Books The Sword in the Stone begins with Wart on a "quest" to find a tutor.
(12) Don was racing the Dodge through the Bonneville Salt Flats , where Gary Gabelich had just (on 23 October) broken the land-speed record.
(13) The time course for these events suggested that the genetic code for synthesis of thymidine kinase can be expressed before "cores" are broken down, but the DNA-polymerase can be synthesized only after liberation of the viral DNA.
(14) Chemical analyses of the radioactive species in the incubation medium showed that a considerable portion of the radiolabeled sugar nucleotide had broken down to cytidine, phosphoric acid, and sialic acid.
(15) She also said that US embassy officials and doctors – who had been blocked from seeing Chen – met him on Friday.said that They said Chen had three broken bones from his escape, and his foot was in a cast.
(16) The size of the broken stone fragments was less than 2 mm in 24 cases (68.5%) and 2 to 5 mm in 10 cases (28.6%), which indicated that the procedure was very effective.
(17) Mohammed Salama, 23, an Al Ahly ultra whose leg was broken in the stadium riot, said it became clear at half-time in the match between the two historical foes that trouble was brewing.
(18) "For so long, management kept us down; they've broken us and bullied us," he said.
(19) Patrick Vieira, captain and on-pitch embodiment of Wenger’s reign, won the trophy with the last kick of his career at the club in the season when the Arsenal-United axis was finally broken by Chelsea at the top of the Premier League.
(20) Trierweiler has broken a fundamental principle of French political life, an unwritten law inherited from the Ancien Régime and perpetuated by France's revolutionary nomenklatura, that the private life – and by that I mean sex life – of a public figure must remain inviolable.
Inoperative
Definition:
(a.) Not operative; not active; producing no effects; as, laws renderd inoperative by neglect; inoperative remedies or processes.
Example Sentences:
(1) Subjects were 56 therapies for HCCs in 48 cases, who were diagnosed as inoperative HCCs, and were performed chemotherapy, transcatheter hepatic arterial embolization (TAE) and percutaneous ethanol injection therapy (PEIT).
(2) Filamentation continued in dif mutants in which SOS-associated division inhibitors were inoperative, which showed that induction of these inhibitors was not the primary cause of filamentation.
(3) If this pressure persisted until the start of the expansion, it would make the opercular suction pump inoperative, because it would blow away the flexible opercular flap which, as a passive valve, seals the widening opercular slit during abduction.
(4) We investigated the incidence and endoscopic features of gastroduodenal lesions which appeared after transcatheter arterial chemo-embolization (TACE), performed 29 times in 25 patients with inoperative hepatocellular carcinoma.
(5) We suggest macrophages may absorb, and thus render inoperative, factors which are necessary for lymphocyte cooperation.
(6) The competitive pattern of this inhibition leads to its being inoperative in ornithine-grown cells, where the intracellular concentration of ornithine is high.
(7) For example, in excised patches of vertebrate rod outer segment plasma membrane, the cGMP-activated cation channels have traditionally been studied in room light because the enzyme cascade linking photon absorption to channel closure was assumed to be inoperative.
(8) Negative feedback of gonadal steroids seems to be inoperative.
(9) Duck erythrocytes treated with norepinephrine in a solution containing 15 mM K+ swell to a new stable cell volume after 60 min, during which time cotransport becomes inoperative.
(10) Such results, obtained from birds in which testosterone feedback was inoperative, indicate that the gonadostimulatory effect of long daylengths in intact males must be mediated, at least in part, by an androgen feedback-independent mechanism.
(11) Induction of recA or polA1 cells by nalidixic acid does not result in the appearance of pol I*, but lexA or recA mutants that are constitutive for SOS functions constitutively express pol I* and mutants which lack functional recA protein produce pol I* when they carry a lexA mutation which renders the lexA repressor inoperative.
(12) Indication of this therapy has been fundamentally limited to the inoperative cases in which patient performance status has deteriorated.
(13) Hence, regulatory mechanisms, inoperative in vitro, probably function in vivo to prevent immune activation of self-recognizing lymphocytes and autoimmunity.
(14) We suggest as an explanation that the majority of daughter strand gap-filling is error free and that mutations arise through a minor error-prone repair pathway which is inoperative under these conditions.
(15) Previous studies demonstrated that hen erythrocytes have an inoperative, latent sphingomyelinase which is activated when the cells are hemolyzed in a hypotonic medium.
(16) It is concluded that the epsilon proofreading subunit of DNA polymerase III holoenzyme is excluded, inhibited, or inoperative during misincorporation and mutagenesis after UV.
(17) One-hundred and eleven species and three species varieties belonging to 39 genera were collected from 50 dust samples on the five media used at 28 degrees C. Using the hair-baiting technique with horse hair, 10 species of Chrysosporium were isolated: C. asperatum, C. state of Arthroderma tuberculatum, C. indicum, C. inops, C. keratinophilum, C. merdarium, C. pannorum, C. queenslandicum, C. tropicum and C. xerophilum.
(18) In such cells the PGK step presumably was inoperative due to total lack of substrate; 2,3-diphosphoglycerate (2,3-DPG) then became the sole substrate source for remaining steps in glycolysis.
(19) This is due to two mutations, one inactivating ATP-driven sodium transport and a second rendering NaH-antiport inoperative.
(20) First, as with the measurements of pulmonary function (Chapter 12), the initial lack of training in adequate maintenance was responsible for inoperative instruments.