(n.) A compound of bromine with a positive radical.
Example Sentences:
(1) The effect of ipratropium bromide administered at two dosage levels, 40 and 80 mug, isoproterenol, 150 mug, and placebo using a metered dose inhaler was evaluated in ten adult patients with asthma in a double-blind, crossover study.
(2) A semiautomated colorimetric assay (MTT assay), based on the ability of live cells to reduce a tetrazolium-based compound, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT), to a purplish colored formazan product that can be measured spectrophotometrically, has recently been adapted for use in drug sensitivity analysis of cultured human tumor cell lines.
(3) Samples of raw cereals imported in Italy and of other foodstuffs that can be treated with bromine-containing fumigants were analysed for the total bromide content.
(4) Uptake into arterial collagens and release of labeled hydroxyproline were then measured after 2.5 h. The relative amounts of types I and III collagens were assessed from the levels of cyanogen-bromide-derived peptides alpha 1(I)CB8 and alpha 1(III)CB5, respectively, after sodium dodecyl sulfate polyacrylamide gel electrophoresis.
(5) The use of SDS-polyacrylamide gel electrophoresis of the cyanogen bromide derived peptides from fibrous cartilage collagens enabled to calculate type I to type II collagen ratio in this tissue.
(6) The patients received no premedication or basic anaesthesia and relaxation was obtained using pancuronium bromide.
(7) The inhibitory phase was blocked by atropine and the excitatory phase was eliminated by tubocurarine chloride, hexamethonium bromide or pindolol.
(8) We conducted a randomized, double-blind, placebo-controlled study of the effect of a new anticholinergic agent, oxitropium bromide, on bronchoconstriction induced by inhaled propranolol in seven subjects with mild asthma 24 to 39 yr of age.
(9) Ten copies of HIV-1 DNA could be detected by PCR-EIA (42 fluorescent units with a background of 18 fluorescent units) compared with a detection limit of 1000 copies by ethidium bromide-stained agarose gel.
(10) Because previous work has shown that radioisotope release from parasites may be nonspecific, separate experiments were performed to determine the cytotoxicity of LAK cells against antibody-coated trophozoites by using ethidium bromide-acridine orange staining to assess effector cell damage.
(11) Key intermediate of the synthesis was 2-formyl-estradiol (2) which was prepared in quantitative yield through reaction of the phenoxymagnesium bromide of estradiol with formaldehyde in the presence of HMPA.
(12) The relative standard deviations for bromide at 10(-7) M and for iodide at 10(-8) M concentration were 1.9% and 3.0%, respectively, using a 10-mL sample for the determination without preconcentration.
(13) This enhancement of the release of radioactivity was inhibited by phospholipase A2 inhibitors, quinacrine (1 mM) and p-bromophenacyl bromide (10 microM), suggesting that polyethylenimine and polyallylamine activates phospholipase A2 to generate arachidonate and its metabolites.
(14) Plasmid sequences were readily observed by ethidium bromide staining of cellular DNA after restriction endonuclease digestion and agarose gel electrophoresis.
(15) Cytochemical localization of ovoperoxidase activity with diaminobenzidine revealed almost a total lack of staining of FEs from bromide-substituted sea water.
(16) Cells were exposed to chlorhexidine, hydrogen peroxide and sodium hypochlorite for 15 min and cell viability was assessed 24 h later with a colorimetric assay which utilizes the tetrazolium salt 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT).
(17) The sequence was obtained from analysis of peptides isolated from chymotryptic, cyanogen bromide, and limited acid cleavages of the protein.
(18) The latter compounds were reduced with lithium aluminium hydride to the respective amines (II a-c) and then N-alkylated by reaction with 2-propynyl-, 2-butynyl- or 2,3-butadienyl bromides to the corresponding amines (III a-j).
(19) When the detergents with aliphatic hydrophobic residues were compared, a cationic detergent cethylmethylammonium bromide (CTAB) was more toxic than non-ionic or anionic detergents.
(20) Cyanogen bromide cleavage of the 145000 subunit produced a single peptide of Mr 75000.
Bromism
Definition:
(n.) A diseased condition produced by the excessive use of bromine or one of its compounds. It is characterized by mental dullness and muscular weakness.
Example Sentences:
(1) Serum bromide levels achieved, however, were far below those reported to result in clinical bromism.
(2) The data, therefore, also suggest that there is not a causal relationship between halothane biotransformation and the clinical syndrome of bromism.
(3) The clinical features and treatment of three suicidal Obral overdoses and of two patients presenting with bromism are presented.
(4) Hyperchloremia may reveal bromism during the neonatal period.
(5) The high frequency of acute intoxications and carbromal induced bromism stresses the need to bring these preparations under prescription.
(6) This case of bromism in a dog suggests that the dosage of potassium bromide should be based on serial measurement of serum bromide concentrations.
(7) The authors report on two cases of neonatal bromism.
(8) When conscious change is due to bromism, hemodialysis instead of forced hydration and diuresis should be performed immediately.
(9) The case demonstrates that, while chronic bromism has become rare, it should still be included in the differential diagnosis, even after intake of supposedly harmless medication.
(10) After diagnosis and treatment of the bromism, they were able to continue living at home.
(11) Although cold syrup containing dextromethorpan bromide is widely administered, the bromism due to cold syrup has not been reported.
(12) We maintain that bromism is not a relic of the past but rather a serious problem in some countries and a potential one in ours.
(13) This article reviews the analytical methodology as it developed historically, and traces the application of chemical analysis of body fluids to monitoring for bromide toxicity (bromism) and then to investigation of the blood-brain barrier in various disorders of the central nervous system.