What's the difference between brown and hemin?

Brown


Definition:

  • (superl.) Of a dark color, of various shades between black and red or yellow.
  • (n.) A dark color inclining to red or yellow, resulting from the mixture of red and black, or of red, black, and yellow; a tawny, dusky hue.
  • (v. t.) To make brown or dusky.
  • (v. t.) To make brown by scorching slightly; as, to brown meat or flour.
  • (v. t.) To give a bright brown color to, as to gun barrels, by forming a thin coat of oxide on their surface.
  • (v. i.) To become brown.

Example Sentences:

  • (1) A former Labour minister, Nicholas Brown, said the public were frightened they "were going to be spied on" and that "illegally obtained" information would find its way to the public domain.
  • (2) Future Brown have connections in the fashion industry, last year soundtracking a surreal film for the brand Telfar.
  • (3) Phenotypic relationships were examined between final score and 13 type appraisal traits and first lactation milk yield from 2935 Ayrshire, 3154 Brown Swiss, 13,110 Guernsey, 50,422 Jersey, and 924 Milking Shorthorn records.
  • (4) But the wounding charge in 2010 has become Brown's creation of a structural hole in the budget, more serious than the cyclical hit which the recession made in tax receipts, at least 4% of GDP.
  • (5) Brown's model, which goes far further than those from any other senior Labour figure, and the modest new income tax powers for Holyrood devised when he was prime minister, edge the party much closer to the quasi-federal plans championed by the Liberal Democrats.
  • (6) One of the most interesting aspects of the shadow cabinet elections, not always readily interpreted because of the bizarre process of alliances of convenience, is whether his colleagues are ready to forgive and forget his long years as Brown's representative on earth.
  • (7) There was also a significant increase in the mitochondrial proton conductance pathway of brown adipose tissue, assessed from the binding of guanosine diphosphate (GDP) to mitochondria isolated from the interscapular (89% above control) and perirenal and para-aortic depots (130%).
  • (8) When faced with a big dilemma, the time-honoured tradition of politicians is to order an inquiry, and that is what Browne expects.
  • (9) Gordon Brown believes that the fact of the G20 summit has persuaded many tax havens, such as Switzerland and Liechtenstein, to indicate that they will adopt a more open approach.
  • (10) What is Obama doing about the prejudice and violence faced by brown people here at home?
  • (11) His wrists were shown wrapped in tape with “MIKE BROWN” and “MY KIDS MATTER” written on them.
  • (12) The dumplings could also be served pan-fried in browned butter and tossed with a bitter leaf salad and fresh sheep's cheese for a lighter, but equally delicious option.
  • (13) October 27, 2013 7.27pm GMT Around the league And here’s how things look elsewhere, as we head into the fourth quarter: Cowboys 13-7 Lions Browns 17-20 Chiefs Dolphins 17-20 Patriots Bills 10-28 Saints Giants 15-0 Eagles 49ers 35-10 Jaguars 7.25pm GMT End of 3rd quarter: 49ers 35-10 Jaguars The quarter ends with the Jaguars facing a third-and-one at their own 32.
  • (14) The announcement on feed-in tariffs will be welcomed by Labour backbenchers, who staged the biggest revolt of Gordon Brown's leadership over the issue.
  • (15) He was fighting to breathe.” The decision on her father’s case came just 10 days after a grand jury in Ferguson, Missouri, found there was not enough evidence to indict a white police officer for shooting dead an unarmed black teenager called Michael Brown.
  • (16) The morning papers, like many papers last week, were full of stories about Brown's survival chances.
  • (17) Ultimately, both Geffen and Browne turned out to be correct: establishing the pattern for Zevon's career, the albums sold modestly but the critics loved them.
  • (18) Despite tthree resignations and his reputation as a tribal operator in the Blair-Brown wars, however, his belief in the party he joined on his 15th birthday is undimmed.
  • (19) Besides the rough, wrinkled, and brown or black surface of the fingertips, microwrinkles of the epidermis occur on the skin ridges, which have so far not been described.
  • (20) This, Brown jokes, counts as good weather for Scotland.

Hemin


Definition:

  • (n.) A substance, in the form of reddish brown, microscopic, prismatic crystals, formed from dried blood by the action of strong acetic acid and common salt; -- called also Teichmann's crystals. Chemically, it is a hydrochloride of hematin.

Example Sentences:

  • (1) The appearance of an abundant class of polyribosomes was correlated with globin synthesis by demonstrating that a discrete class of polyribosomes arises in cells treated with the inducers hexamethylene bisacetamide and hemin.
  • (2) Finding (d) indicates that steps involved in the restorative effect of these compounds may not contribute to the stimulation of the globin synthesis in hemin-deficient lysates.
  • (3) The destabilization of the red cell membrane skeleton in the presence of crude iHCR is caused by release of hemin, which lowers the stability of membrane skeleton by weakening the spectrin-protein 4.1-actin interaction.
  • (4) Hemin failed to increase P450 levels previously depressed by TPA indicating that TPA acts by lowering apocytochrome levels.
  • (5) Prior exposure of the adherent cell layer to high concentrations of hemin (10 microM) was found to have a beneficial effect on the support of newly seeded cultures; however, the effect of lower hemin concentrations (0.1-1 microM) on stromal cell layer formation was not significant.
  • (6) Hemin increased satellite cell fusion by 27%, but decreased cell proliferative rate by 30%.
  • (7) Inhibition of hemin-mediated O2 activation by bovine superoxide dismutase and the copper tetrammine complex has been examined.
  • (8) Upon incubation of the HCI preparation with hemin (5-10 microM), the eIF-2 alpha kinase is converted into an inactive form and appears to become associated with related peptides forming high molecular weight complexes which can be reversibly activated by 2-mercaptoethanol.
  • (9) When the prorepressor is converted to the hemin-controlled translational repressor, either by prolonged warming in the absence of hemin or by incubation with N-ethylmaleimide for 5 min, and then incubated briefly with [gamma-32P]-ATP and Mg2+, a protein that migrates as a 100 000 molecular weight component on sodium dodecyl sulfate-polyacrylamide gels becomes phosphorylated.
  • (10) Its activity is independent of cyclic AMP as well as of the calcium-dependent regulator protein and is inhibited by hemin.
  • (11) The spin-labeled hemins were recombined with apoproteins of hemoglobin (Hb), myoglobin (Mb), cytochrome c peroxidase (EC 1.11.1.5) and horseradish peroxidase (EC 1.11.1.7).
  • (12) A model compound with similar optical properties to the CO-ligated protein can be prepared in dimethyl sulfoxide from hemin chloride, imidazole, and CO using chromous acetate as the heme reductant.
  • (13) Porphyromonas gingivalis is capable of in vitro growth when iron sources are either complexed to hemin or host iron transport proteins, or exist in an inorganic form.
  • (14) An assumption is advanced that the P. vitale catalase contains two hemin groups located in two protein subunits.
  • (15) The effect of hemin administration on the level of hepatic delta-amino-levulinate synthase mRNA was also examined.
  • (16) We were not able to detect any reaction between the radical (see article) and the hemin group (which would result in a complex such as heme O-2).
  • (17) The N-acetylimidazole-reacted apoprotein supplemented with hemin and reacted with hydroperoxides, neither showed electronic absorption spectra of higher oxidation states nor an EPR doublet signal due to a tyrosyl radical.
  • (18) With iron porphyrins (hemin, heme and their complexes) the charge of the iron and the nature of axial ligands determine the position and intensity of the O-bands in the MOR spectrum.
  • (19) Since S. typhimurium LT2 is not able to incorporate hemin, the identification of the mutants not stimulated by Delta-ALA was made on the basis of the simultaneous loss of catalase activity and cytochromes.
  • (20) Hemin, known to inactivate IRF in vivo, showed a similar, reversible effect in vitro, presumably by oxidizing IRF.

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