(a.) Grievous to be borne; causing uneasiness or fatigue; oppressive.
Example Sentences:
(1) Although Menzies, et al., report that survival rates are higher than previously expected and that in most cases the children's and parents' lives appear not to be excessively burdensome, the Working Group contends that there "continues to be ethical justification for selective treatment" of such newborns.
(2) So if some trustees feel that increased demands on their time will be too burdensome, it best to leave the field open to others.
(3) It would reduce burdensome regulation on business and help rebalance the economy towards exports.
(4) Collection, storage and retrieval of large amounts of data from multiple experiments for subsequent reduction, graphing and statistical analysis need not be a burdensome task.
(5) Eventual mastery of the burdensome experience involves reorganization of the individual's "assumptive world," namely of his intrapsychic maps of external reality and his internal system for guiding and motivating his behavior, which have been disorganized by the loss of their anchorage in the ruptured attachment.
(6) While these ethical responsibilities can be overwhelmingly burdensome, they can also be opportunities.
(7) Close collaboration between toxicologists and the authorities responsible for drawing up toxicological regulations is called for in order to ensure that the rules applied during the important and fascinating process of discovering and developing new drugs do not become unnecessarily burdensome.
(8) Should, then, oven manufacturers pay electricity companies for all that burdensome work they have to do to keep ovens working – especially when lightbulbs are so low-strain?
(9) As part of our long-term economic plan, we will sweep away burdensome red tape, get heavy handed regulators off firms’ backs and create a small business conciliation service to help resolve disputes.” It is estimated that small businesses are owed £32bn in late payments but are often unaware of their rights or are reluctant to take legal action, fearing they will lose future business.
(10) A large aspect of the research has been interviewing businessmen and women confronted by the burdensome issue of what to do with more money than they could ever spend in a lifetime.
(11) "Over 70% of firms see dismissal rules as burdensome to their business.
(12) Struggling businesses must be liberated from burdensome environmental regulations.
(13) Regulations, especially employment regulations, are particularly burdensome for small businesses and these should be radically simplified.
(14) Efforts to quash the subpoena require proof that the materials requested are irrelevant to the case, not subpoenaed for "good cause," or that compliance would be unduly oppressive and burdensome.
(15) It’s an attempt to withhold abortion from nearly all women in the US through burdensome regulation intended to stop insurers from covering abortions.
(16) The Red Tape Challenge states proposals will be reviewed by a ministerial “Star Chamber” with the presumption that burdensome regulations would disappear go unless they could be justified.
(17) The equation for the calculation of E from measured PET data is mathematically complex and its direct application in the generation of PET images of either E or the CMRO2 on a pixel-by-pixel basis is computationally burdensome.
(18) Several important advances have made the process more practical and acceptable: computer programs that eliminate the need for burdensome calculations, improved techniques for designing analytic models, the ability to carry out sensitivity analyses over several dimensions simultaneously, and the elaboration of clinically relevant measures of utility.
(19) In real dollar terms, Medtronic's taxes did not appear burdensome.
(20) Fifty % of the primary care-givers experienced their situation as not so burdensome, 25% as rather and also 25% as very burdensome.
Difficult
Definition:
(a.) Hard to do or to make; beset with difficulty; attended with labor, trouble, or pains; not easy; arduous.
(a.) Hard to manage or to please; not easily wrought upon; austere; stubborn; as, a difficult person.
(v. t.) To render difficult; to impede; to perplex.
Example Sentences:
(1) Virtually every developed country has some form of property tax, so the idea that valuing residential property is uniquely difficult, or that it would be widely evaded, is nonsense.
(2) Although solely nociresponsive neurons are clearly likely to fill a role in the processing and signalling of pain in the conscious central nervous system, the way in which such useful specificity could be conveyed by multireceptive neurons is difficult to appreciate.
(3) In practice, however, the necessary dosage is difficult to predict.
(4) Cor triatriatum (CT) is a rare congenital defect, surgically correctable, and sometimes difficult to diagnose by cardiac catheterization.
(5) By drawing from the pathophysiology, this article discusses a multidimensional approach to the treatment of these difficult patients.
(6) Past imaging techniques shown in the courtroom have made the conventional rules of evidence more difficult because of the different informational content and format required for presentation of these data.
(7) The way we are going to pay for that is by making the rules the same for people who go into care homes as for people who get care at their home, and by means-testing the winter fuel payment, which currently isn’t.” Hunt said the plan showed the Conservatives were capable of making difficult choices.
(8) In many cases, physicians seek to protect themselves from involvement with these difficult, highly anxious patients by making a referral to a psychiatrist.
(9) The diagnosis of variant- or Prizmetal-angina is difficult because if insufficient specificity of the tests.
(10) The detection of these antibodies is difficult owing to the lack of standardization and of specificity of the laboratory tests.
(11) It was so difficult to keep a straight face when I was filming a sauna scene with Roy Barraclough, who played the mayor of Blackpool.
(12) That is, he believes, to look at massively difficult, interlocking problems through too narrow a lens.
(13) Conversion of the active-site thiol to thiocyanate makes it more difficult to inactivate the enzyme by treatment with Cd2+.
(14) If they end up going to another club that is difficult to take.
(15) Cigarette consumption has also been greater in urban areas, but it is difficult to estimate how much of the excess it can account for.
(16) The most difficult thing I've dealt with at work is ... the terminal illness of a valued colleague.
(17) In that respect, it's difficult to see Allen's anthem as little more than same old same old, and it's probably why I ultimately feel she misses the mark.
(18) This hypothesis is difficult to substantiate with direct measurements using human subjects.
(19) Extrapolation of gestational age from early crown-rump lengths (CRLs) has been difficult because previously established tables of CRL versus gestational age have contained few measurements at less than seven to eight weeks from the first day of the last menses.
(20) Companies had made investments in certain energy sources, the president said, so change could be “uncomfortable and difficult”.