(n.) A fall of water over a precipice, as in a river or brook; a waterfall less than a cataract.
(v. i.) To fall in a cascade.
(v. i.) To vomit.
Example Sentences:
(1) With fields and fells already saturated after more than four times the average monthly rainfall falling within the first three weeks of December, there was nowhere left to absorb the rainfall which has cascaded from fields into streams and rivers.
(2) The following model is suggested: exogenous ATP interacts with a membrane receptor in the presence of Ca2+, a cascade of events occurs which mobilizes intracellular calcium, thereby increasing the cytosolic free Ca2+ concentration which consequently opens the calcium-activated K+ channels, which then leads to a change in membrane potential.
(3) Each point of the interleukin cascade reaction was examined.
(4) All cellular signals characterized so far are reverted during retrodifferentiation: Redistribution of PKC and down-regulation of c-fos and c-jun contribute to an interruption of the differentiation-associated transsignaling cascade.
(5) Present antihypertensive therapy is directed largely at secondary factors dependent upon or influencing the primary phospholipase C cascade.
(6) Since testosterone influenced both tissue stores and PDBu-stimulated secretion of LHRH and GAP, this steroid may selectively regulate biosynthesis and secretion of pro-LHRH-derived peptides through activation of the metabolic cascade involving the PKC system.
(7) Extracellular signals that promote cell growth activate cascades of protein kinases.
(8) Using serine proteinase inhibitors and antibodies to plasminogen activators as well as a newly described collagenase inhibitor we demonstrate that a protease cascade leads to the activation of an enzyme(s) that cleaves collagen IV.
(9) Low-density lipoprotein (LDL) has a similar hormone-like action and activates the signal transfer cascade that eventually leads to platelet aggregation as well as vascular smooth muscle cell proliferation.
(10) However, the role of calcium homeostasis in regulating several biochemical pathways implicated in other steps of the metastatic cascade suggests that calcium channel antagonists could also inhibit metastasis by other mechanisms.
(11) Since ADH exerts its effects by activation of adenylyl cyclase (AC), further experiments were performed to identify the site at which CP inhibits this cascade.
(12) Autoantibodies which interfere with the function of enzyme cascade systems have also been described in diseases such as acquired haemophilia (anti-factor VIII antibodies) and glomerulonephritis (C3 nephritic factor).
(13) The cyclic adenosine nucleotide pathway is turned off by kinase A activity, whereas the inositol trisphosphate cascade is terminated by kinase C. The data support the concept that desensitization of odorant responses involves phosphorylation of key elements in the transduction cascade.
(14) These hormonal responses trigger a cascade of metabolic adjustments leading to catabolism and substrate mobilization in the postoperative period.
(15) The series filter model is compatible with a simply physical model consisting of cascaded chemical reactions whose forward rate constants are reciprocals of the filter time constants, whose reverse rate constants are negligible, and in which the concentration of an intermediate product controls membrane current.
(16) E capture IC via complement receptors, type 1 (CR1) which can bind to C3b and C4b ligand sites generated on IC during activation of the complement cascade.
(17) The EU was not properly promoting cascade use either he said.
(18) Speculatively, the blockage by dbcAMP of the morphogenetic cascade in the co-cultured system may be related to the inhibition by dbcAMP of testis cord formation in organ cultures of fetal gonads reported by others.
(19) Component of the cascade model represented adventitia and media layers of the wall.
(20) These data suggest that sCR1 inhibits the Arthus reaction by interrupting the activation of the C cascade, hence limiting the detrimental immune complex-induced tissue damage in vivo.
Tier
Definition:
(n.) One who, or that which, ties.
(n.) A chold's apron covering the upper part of the body, and tied with tape or cord; a pinafore.
(v. t.) A row or rank, especially one of two or more rows placed one above, or higher than, another; as, a tier of seats in a theater.
Example Sentences:
(1) Mike Ashley told Lee Charnley that maybe he could talk with me last week but I said: ‘Listen, we cannot say too much so I think it’s better if we wait.’ The message Mike Ashley is sending is quite positive, but it was better to talk after we play Tottenham.” Benítez will ask Ashley for written assurances over his transfer budget, control of transfers and other spheres of club autonomy, but can also reassure the owner that the prospect of managing in the second tier holds few fears for him.
(2) In a triple tier configuration, females concentrated 66% of their travel on the top tier.
(3) Not because we are “chippy, moronic gits” (thank you, Twitter), but because we do not see the social benefit of a two-tier education system that provides a small minority with vastly more opportunities than the rest.
(4) Oregon’s governor on Wednesday signed trailblazing legislation that will raise the minimum wage to nearly $15 in six years, and do so through a three-tiered system that has not been tried anywhere else in the country.
(5) Tier one comprises the nosological diagnosis, and tier two a detailed depiction of the component psychological dysfunctions.
(6) A 28 kDa calcium-binding protein (CaBP, or calbindin-D28 kDa) is expressed in dorsal tier mesostriatal dopaminergic neurons.
(7) A new, two-tier system for biotyping Salmonella typhimurium gives a finer and more reliable differentiation of strains than the Kristensen scheme and is capable of future extension by the addition of new types and new tests.
(8) The first two games from that partnership will be based on the company’s b-tier franchises Animal Crossing and Fire Emblem.
(9) It also represents the legalisation of a two-tiered system of tenants' rights – those who can afford to have rights and those who can't."
(10) Instead it said that the changing of the settings – which previously required users to navigate through up to 150 different settings to control who could see their data, to a simpler four-tiered version plus a "customise" option – was "merely a red herring".
(11) It's a pacey device, and one that serves the game-show content of the novel, and this is a good book; mid-tier King.
(12) The testing found that ATEbank would have a Tier 1 capital ratio of 4.36% under the most adverse scenario, leaving it short of €242.6m.
(13) In the year of the credit crunch, 2007, the bank's crucial tier one ratio – a measure of its financial health – was 4.7%.
(14) Such a compromise would have been difficult to reach even with such a deal, because many Democrats fear it would create a “two-tier” workforce.
(15) This tier system appears to provide a considered and careful approach to the requirement to assess the ocular tolerance of those materials for which conventional animal tests are not essential.
(16) The rhabdom of the larval eye, if cut longitudinally, exhibits a "banded" structure over its entire length; in the adult the banded part is confined to the distal end, and the rhabdom is tiered.
(17) Last month he told MPs on the education select committee he doubted there was any proof of noncompliance with the standards by academies, which Oliver has warned risks creating a two-tier system where some pupils receive healthy food and others do not.
(18) The tier system approach to Subdivision M guidelines allows for an effective screen (Tier I), and for in-depth (Tier II) evaluation of biochemical pesticides as immunotoxic agents.
(19) Auditors are also concerned about the longer-term financial sustainability of single-tier and county councils, reporting that 52% of these authorities are not well placed to deliver their medium-term financial strategies.” The report concludes that the DCLG “does not monitor in a coordinated way the impact of funding reductions on services, and relies on other departments and inspectorates to alert it to individual service failures.
(20) As the government pushes ahead with funding cuts of more than a third in local government, the National Audit Office said many single-tier and county councils feared for core services including education and social care.