(n.) An event producing a subversion of the order or system of things; a final event, usually of a calamitous or disastrous nature; hence, sudden calamity; great misfortune.
(n.) The final event in a romance or a dramatic piece; a denouement, as a death in a tragedy, or a marriage in a comedy.
(n.) A violent and widely extended change in the surface of the earth, as, an elevation or subsidence of some part of it, effected by internal causes.
Example Sentences:
(1) When it was grown, it would bring both ecstasy and catastrophe to women.
(2) The effects of brain injury can be catastrophic and long-term so the impact of more research would be vast, but affected numbers are too small so it loses out.
(3) After violence had run its bloody course, the country’s rulers conceded it had been a catastrophe that had brought nothing but “grave disorder, damage and retrogression”.
(4) Strict precautions are necessary to prevent the catastrophic events resulting from inadvertent gentamicin injection; such precautions should include precise labeling of all injectable solutions on the surgical field, waiting to draw up injectable antibiotics until the time they are needed, and drawing up injectable antibiotics under direct physician observation.
(5) In contrast, the 2009 report, "Chernobyl: Consequences of the Catastrophe for People and the Environment" , published by the New York Academy of Sciences, comes to a very different conclusion.
(6) As a result, low-lying areas, including Bangladesh, Florida, the Maldives and the Netherlands, will undergo catastrophic flooding, while in Britain large areas of the Norfolk Broads and the Thames estuary could disappear.
(7) It is found that, in contrast to most metallic materials yet in keeping with many ceramics, there are no distinct fracture morphologies in pyro-carbons which are characteristic of a specific mode of loading; fracture surfaces appear to be identical for both catastrophic and subcritical crack growth under either sustained or cyclic loading.
(8) In the midst of this catastrophe, the troika is insisting on further austerity to achieve massive primary budget surpluses of 3% in 2015, 4.5% in 2016 and even more in future years.
(9) The first report, released last September in Stockholm , found humans were the "dominant cause" of climate change, and warned that much of the world's fossil fuel reserves would have to stay in the ground to avoid catastrophic climate change.
(10) "We believe that such a path would be catastrophic for the UK, for Europe and for the protection of human rights around the world."
(11) A large number of flight accidents and catastrophes associated with the human factor, high nervous and psychic tension when being on duty, increasing trend towards a greater incidence of psychogenic diseases responsible for pilots to be grounded make it necessary to develop a system of primary psychoprophylaxis of the flying personnel and to help them with various social, psychohygienic and psychoprophylactic measures.
(12) This would sound gilded, except here is Klebold, revisiting every detail in a way that implies it might have been easier on her psychologically if there had been a catastrophe in the household, something pointing to why Dylan did what he did.
(13) Self-help groups can aid an individual in coping with and adapting to catastrophic illness.
(14) Catastrophes, though always regrettable, must be seen as experiments demanding careful analysis and exploitation.
(15) This set was called by the authors a syndrome reflecting an overpowering, but latent, unconscious sense of crisis, of a catastrophe ("Catastrophe-syndrome").
(16) But Blair's address - "history will forgive us" - was a dubious exercise in group therapy: the cheers smacked of pathetic gratitude, as he piously pardoned the legislators, as well as himself, for the catastrophe of Iraq.
(17) I argue that (a) the procedures they used to study confounding were suboptimal because multiple measures of depression and catastrophizing were not employed and (b) the distinctiveness of constructs might better be regarded as a continuous rather than all-or-none (having adequate discriminant validity versus being confounded) concept.
(18) Newborn infants with congenital homozygous protein C deficiency develop catastrophic thrombosis (purpura fulminans) and will not survive beyond the neonatal period without protein C replacement.
(19) But the humanitarian catastrophes in Syria have been overshadowed by stories about Islamic State .
(20) We do not anticipate major impact on psychiatric tasks from some form of catastrophic insurance.
Significance
Definition:
(n.) Alt. of Significancy
Example Sentences:
(1) Once treatment began, no significant changes occurred in Group 1, but both PRA and A2 rose significantly in Groups 2 and 3.
(2) However, patients with GGBHS were significantly older (P less than .05).
(3) In each sheep there was a significant negative correlation between the glucose and corticosteroid concentrations in both maternal and fetal plasma, and there were positive correlations between the maternal and fetal plasma concentrations of glucose, and between the glucose and fructose concentrations of fetal plasma.
(4) Such a decrease significantly biased survival (p = 0.001).
(5) This may have significant consequences for people’s health.” However, Prof Peter Weissberg, medical director of the British Heart Foundation, which funded the work, said medical journals could no longer be relied on to be unbiased.
(6) It is supposed that delta-sleep peptide along with other oligopeptides is one of the factors determining individual animal resistance to emotional stress, which is supported by significant delta-sleep peptide increase in hypothalamus in stable rats.
(7) However, when first trimester specimens were analyzed, the direct-product measurements were significantly larger than the corresponding 3H2O assay results.
(8) The Na+ ionophore, gramicidin, had a small but significant inhibitory effect on Na(+)-dependent KG uptake, demonstrating that KG uptake was not the result of an intravesicular positive Na+ diffusion potential.
(9) Propranolol resulted in a significantly lower mean hourly, mean 24 h and minimum heart rate.
(10) In some other countries the patient-to-nurse ratio was significantly smaller.
(11) The findings indicate that there is still a significant incongruence between the value structure of most family practice units and that of their institutions but that many family practice units are beginning to achieve parity of promotion and tenure with other departments in their institutions.
(12) The significance of minor increases in the serum creatinine level must be recognized, so that modifications of drug therapy can be made and correction of possibly life-threatening electrolyte imbalances can be undertaken.
(13) The process of sequence rearrangement appears to be a significant part of the evolution of the genome and may have a much greater effect on the evolution of the phenotype than sequence alteration by base substitution.
(14) The low affinity of several N1-alkylpyrroleethylamines suggests that the benzene portion of the alpha-methyltryptamines is necessary for significant affinity.
(15) During control, no significant difference between systolic fluctuation (delta Pa) and pleural swings (delta Ppl) was found.
(16) Urinary ANF immunoreactivity was significantly enhanced by candoxatril in both groups (P less than 0.05 and P less than 0.01 in groups 1 and 2, respectively), with a more pronounced effect evident at the higher dose (P less than 0.01).
(17) Both lymph flow from cannulated pancreatico-duodenal lymphatics and intralymphatic pressure in the non-transected ones increased significantly.
(18) We conclude that the priming effect is not a clinically significant phenomenon during natural pollen exposure in allergic rhinitis patients.
(19) This study examined the [3H]5-HT-releasing properties of 3,4-methylenedioxymethamphetamine (MDMA) and related agents, all of which cause significant release of [3H]5-HT from rat brain synaptosomes.
(20) However, the degree of sedation caused by diphenhydramine was significantly greater than that caused by cimetidine (P = .0001).