(n.) Connection of links or union of parts, as in a chain; a regular or connected series. See Concatenation.
Example Sentences:
(1) A tabulation is given of the polynomials for all possible stereoisomers of many of the knotted and catenated forms that are found in DNA.
(2) We present a unified model for the relaxation, catenation, and knotting reactions of topoisomerase I in which the enzyme induces a break in a single-stranded region, but bridges that break with covalent and noncovalent interactions and allows passage of one duplex or single-stranded DNA segment.
(3) Unlike Escherichia coli topoisomerase I (omega), catenation by the HeLa topoisomerase I is not stimulated by gapped circles.
(4) Both the relaxation and the catenation reaction exhibit a salt optimum at 130 mM NaCl.
(5) Our findings suggest the need for closer examination for HPV episomal catenation in other cervical carcinoma cell lines as well as in primary carcinoma tissues of the uterine cervix and the anogenital tract.
(6) At low concentrations of Topo I (sufficient to confer specificity to the replication system for DNA templates containing a ColE1-type origin of DNA replication), the major products of the replication reaction were: multigenome-length, linear, double-stranded DNA molecules (an aberrant product); multiply interlinked, catenated, supercoiled DNA dimers; and a last Cairns-type replication intermediate.
(7) The increase in the number of TR in progeny episomes indicates that linear DNA is produced from concatameric replicative intermediates rather than from amplified catenated circular intermediates.
(8) Crude extracts and partially purified fractions contain an aggregating factor that can substitute spermidine in catenating reactions.
(9) Upon centrifugation of gently lysed T. cruzi cells through a sucrose gradient, a free DNA fraction was shown to contain catenated dimers and knotted DNA structures.
(10) The mitochondrial DNA of trypanosomes is organized as a network of catenated circular DNA molecules called the kinetoplast.
(11) Unexpectedly, deletion of the first Zn finger, a point mutation in the Zn-catenation site in the first finger, or one in the steroid-specificity domain at the base of the first finger converted GR into a dexamethasone-responsive activator that enhanced basal and interleukin 1-induced IL-6 promoter function.
(12) The results are consistent with the idea that DNA-binding sites are fixed on the scaffold and mediate catenation of bound DNA circles by holding them in close proximity to each other.
(13) Ellipticine in particular produced these catenated dimers rapidly and efficiently.
(14) Consequently, the relaxation activity was almost the same between the RL and AH fractions, whereas the catenation activity was much higher in the AH fraction.
(15) For a DNA circle nicked at a unique location, the efficiency of DNA breakage opposite the nick correlates with the rate of catenation.
(16) This procedure liberates linearized minicircle molecules from network catenation, distributing them throughout the lysate, and allowing a small aliquot of the original lysate to be analyzed by PCR amplification.
(17) In vitro, the complexity of catenated products was linearly proportional to substrate supercoil density.
(18) These newly synthesized strands were not part of two catenated interlocked SV40 monomers suggesting that the block occurred prior to the final ligation reaction.
(19) Hypertonic medium appeared to inhibit both DNA unwinding in the termination region and separation of catenated dimers.
(20) MtDNA (monomeric and catenated dimeric forms) in transformed and uninfected CEF replicate by displacement synthesis.
Element
Definition:
(n.) One of the simplest or essential parts or principles of which anything consists, or upon which the constitution or fundamental powers of anything are based.
(n.) One of the ultimate, undecomposable constituents of any kind of matter. Specifically: (Chem.) A substance which cannot be decomposed into different kinds of matter by any means at present employed; as, the elements of water are oxygen and hydrogen.
(n.) One of the ultimate parts which are variously combined in anything; as, letters are the elements of written language; hence, also, a simple portion of that which is complex, as a shaft, lever, wheel, or any simple part in a machine; one of the essential ingredients of any mixture; a constituent part; as, quartz, feldspar, and mica are the elements of granite.
(n.) One out of several parts combined in a system of aggregation, when each is of the nature of the whole; as, a single cell is an element of the honeycomb.
(n.) One of the smallest natural divisions of the organism, as a blood corpuscle, a muscular fiber.
(n.) One of the simplest essential parts, more commonly called cells, of which animal and vegetable organisms, or their tissues and organs, are composed.
(n.) An infinitesimal part of anything of the same nature as the entire magnitude considered; as, in a solid an element may be the infinitesimal portion between any two planes that are separated an indefinitely small distance. In the calculus, element is sometimes used as synonymous with differential.
(n.) Sometimes a curve, or surface, or volume is considered as described by a moving point, or curve, or surface, the latter being at any instant called an element of the former.
(n.) One of the terms in an algebraic expression.
(n.) One of the necessary data or values upon which a system of calculations depends, or general conclusions are based; as, the elements of a planet's orbit.
(n.) The simplest or fundamental principles of any system in philosophy, science, or art; rudiments; as, the elements of geometry, or of music.
(n.) Any outline or sketch, regarded as containing the fundamental ideas or features of the thing in question; as, the elements of a plan.
(n.) One of the simple substances, as supposed by the ancient philosophers; one of the imaginary principles of matter.
(n.) The four elements were, air, earth, water, and fire
(n.) the conditions and movements of the air.
(n.) The elements of the alchemists were salt, sulphur, and mercury.
(n.) The whole material composing the world.
(n.) The bread and wine used in the eucharist or Lord's supper.
(v. t.) To compound of elements or first principles.
(v. t.) To constitute; to make up with elements.
Example Sentences:
(1) Elements in the skin therefore seemed to enhance nerve regeneration and function.
(2) It has been generally believed that the ligand-binding of steroid hormone receptors triggers an allosteric change in receptor structure, manifested by an increased affinity of the receptor for DNA in vitro and nuclear target elements in vivo, as monitored by nuclear translocation.
(3) Four other independent LCMV-GP2(275-289) specific H-2Db-restricted CTL clones also expressed V alpha 4 and V beta 10 gene elements.
(4) Community involvement is a key element of the Primary Health Care (PHC) approach, and thus an essential topic on a course for managers of Primary Health Care programmes.
(5) Thus, human bronchial epithelial cells can express the IL-8 gene, with expression in response to the inflammatory mediator TNF regulated mainly at the transcriptional level, and with elements within the 5'-flanking region of the gene that are directly or indirectly modulated by the TNF signal.
(6) According to the finite element analysis, the design bases of fixed restorations applied in the teeth accompanied with the absorption of the alveolar bone were preferred.
(7) To determine the influence of cetylpyridinium chloride (CPC) adsorption on the wettability and elemental surface composition of human enamel, with and without adsorbed salivary constituents, surface-free energies and elemental compositions were determined.
(8) Second, the unknown is searched against the database to find all materials with the same or similar element types; the results are kept in set 2.
(9) It is concluded that selection against insertional mutations is unlikely to be the major factor involved in the containment of element abundance.
(10) We have investigated interactions between the erythroid transcription factor GATA-1 and factors binding two cis-acting elements commonly linked to GATA sites in erythroid control elements.
(11) Further, Tyr 20 is an important element of that sequence.
(12) It is possible that the elements provide common precursor proteins that reach the secretory intermediate lobe cells through their dendritic branches.
(13) Other than failing to get a goal, I couldn’t ask for anything more.” From Lambert’s perspective there was an element of misfortune about the first and third goals, with Willian benefitting from handy ricochets on both occasions.
(14) These data indicate that the sfrB gene product is a regulatory element, since the single gene product elicits the expression of genes for many products for F expression and lipopolysaccharide synthesis.
(15) Therefore, a hormonal regulatory element can discriminate among closely related transcription start sites.
(16) The safe motherhood initiative demands an intersectoral, collaborative approach to gynecology, family planning, and child health in which midwifery is the key element.
(17) The 500-bp element arose by duplication of one half of a 180-bp ancestor and insertion of a foreign segment between the two duplicated parts followed by amplification.
(18) Neither light nor electron microscopy revealed significant morphologic alterations in the cochlear elements of the exposed offspring.
(19) The hypothesis that the standard acoustic startle habituation paradigm contains the elements of Pavlovian fear conditioning was tested.
(20) Autopsy revealed a primary intimal sarcoma with osteogenic elements arising in the posterior leaflet of the pulmonary valve and obstructing the main pulmonary artery and its right branch.