(1) The promoters of the adenovirus 2 major late gene, the mouse beta-globin gene, the mouse immunoglobulin VH gene and the LTR of the human T-lymphotropic retrovirus type I were tested for their transcription activities in cell-free extracts of four cell lines; HeLa, CESS (Epstein-Barr virus-transformed human B cell line), MT-1 (HTLV-I-infected human T cell line without viral protein synthesis), and MT-2 (HTLV-I-infected human T cell line producing viral proteins).
(2) The clinical presentation of the disease and the results of treatment in 48 patients with metastases at diagnosis of Ewing's sarcoma, entered into the Cooperative Ewing's Sarcoma Studies (CESS) 1981 and 1986 of the German Society of Pediatric Oncology (GPO), were analysed.
(3) These results are similar to those obtained in 59 patients treated from 1979 to 1982 (average follow-up, 10 years) using the same drugs administered according to adjuvant chemotherapy procedure as well as those reported in the only other large study on this subject in the literature (the multi-institution German study CESS-81).
(4) By this method, preoperative localization of the insulin producing pancreatic islet cell tumor was su-cessfully performed.
(5) The same DNA fragment directed cell-specific transcription of the IL-2 receptor gene in extract of HTLV-I-infected T cells, MT-1, but not of Epstein-Barr virus-transformed B cells, CESS.
(6) MSF said case numbers had dropped in the Liberian capital, Monrovia, where there was now surplus bed capacity, but added that many international agencies “seem unable to adapt to the rapidly changing situation” with outbreaks in Bong, Margibi, Gbarpolu, Grand Cape Mount and River Cess counties.
(7) The toxicity of the VAIA regimen was comparable with that of the conventional vincristine, actinomycin D, cyclophosphamide, and adriamycin (VACA) regime used in the previous CESS 81 trial.
(8) Histamine increases the IL-6 binding by CESS cells and inhibits that by U937 and HepG2 cells.
(9) In CESS 86, however, the results after radiation therapy have been improved markedly (3-year RFS 67% after radiation therapy, 65% after surgery, and 62% after resection plus irradiation).
(10) The effects of the supernatants obtained from culture fluids of the ATL cells and the T-cell lines on IgG production of a human B-cell line, CESS cells, were also examined.
(11) IgA-specific suppressive activity was absorbed with human B blastoid cells bearing surface IgA (Dakiki) but not with those bearing surface IgG (CESS) or murine and human T cell line cells (BW5147, L5178Y, HPB-ALL, and MOLT4), indicating that IgA-BF interact with B cells bearing IgA to suppress their differentiation.
(12) In contrast, PA317 and GH3 IL 6 were 230 and 6.7 times more effective than COS-7 IL 6 in inducing Ig production in CESS cells.
(13) Supernatant from the human bladder carcinoma line T-24 contains a B-cell differentiation factor (BCDF) able to induce immunoglobulin secretion from CESS cells.
(14) At present, Kaplan-Meier disease-free survival projects that disease-free survival in patients with large primary tumors has improved compared with that reported for the previous CESS 81 trial.
(15) Supernatants (Sups) of culture fluids of ATL cells from 4 patients and those of 2 T-cell lines were added at various concentrations to the CESS cells.
(16) IL-6 was found 1 degree to stimulate immunoglobulin A production by the CESS B cell line up to 19 fold without being affected by the presence of IL-1 beta and 2 degrees to stimulate murine thymocytes proliferation up to 2-4 fold, with an increase up to 60-fold in costimulation with either IL-1 alpha or beta.
(17) CESS, L4 and BALM4 all increased IgG production in response to partially purified B cell growth factor (Cellular Products, Inc., Sera-Lab., Crawley Down, GB) and B cell differentiation factor-containing supernatant from the T24 bladder carcinoma cell line.
(18) Studies of Ebstein-Barr virus-transformed B cell lines showed that IFN-alpha caused a similar effect on the CESS line as on peripheral blood B cells, with low dose enhancement and high dose suppression of Ig production.
(19) A low-frequency suppressor-cell population in normal peripheral blood inhibits the B-cell CESS response to IL-6, following pokeweed mitogen stimulation.
(20) When SPL were cultured with OK-432 for 24 h in serum-free T medium, the cell-free supernatant induced production of IgM in the SKW6.CL-4 and IgG in the CESS human B cell line, while no such activity was detected in unstimulated SPL culture.
Sleeper
Definition:
(n.) One who sleeps; a slumberer; hence, a drone, or lazy person.
(n.) That which lies dormant, as a law.
(n.) A sleeping car.
(n.) An animal that hibernates, as the bear.
(n.) A large fresh-water gobioid fish (Eleotris dormatrix).
(n.) A nurse shark. See under Nurse.
(n.) Something lying in a reclining posture or position.
(n.) One of the pieces of timber, stone, or iron, on or near the level of the ground, for the support of some superstructure, to steady framework, to keep in place the rails of a railway, etc.; a stringpiece.
(n.) One of the joists, or roughly shaped timbers, laid directly upon the ground, to receive the flooring of the ground story.
(n.) One of the knees which connect the transoms to the after timbers on the ship's quarter.
(n.) The lowest, or bottom, tier of casks.
Example Sentences:
(1) Chapman and the other "illegals" – sleeper agents without diplomatic cover – seem to have done little to harm American national security.
(2) Just by adding a sofa, table and chairs and some plants, we have turned this house into a home, and solved the housing crisis for one of the 6,500 rough sleepers or thousands of other homeless people in London.
(3) Thirteen sleep-onset insomniacs and nine good sleepers were selected to differ only in their sleep-onset latencies as confirmed by polysomnography.
(4) Deutsche Bahn, the German rail provider, confirmed this month that its City Night Line sleeper trains on the Climate Express route would cease from 1 November, while the night train that connects Paris to Berlin, Hamburg and Munich will be stopped from December.
(5) Individuals complaining of disturbed sleep that was verified by polysomnographic indices (objective DIMS) and a group with complaints of disturbed sleep in the absence of objective findings (subjective DIMS) were compared with normal sleepers.
(6) Nets and sleepers were rotated between huts on different nights, the design being based on a series of Latin squares and conducted double-blind.
(7) A significant difference was observed in the sleep pattern of the patients with nocturnal attacks (who were good sleepers and received no anticonvulsants) and healthy controls.
(8) Fifty-six poor sleepers, aged from 20 to 30, were compared with 46 good sleepers of the same age regarding objective sleep parameters and personality.
(9) Despite claims of being "light" sleepers who are easily awakened by noise, poor sleeper auditory arousal thresholds were the same as those of good sleepers.
(10) However, when the distribution of body movements through the night was considered, the dynamic of nocturnal motor activity typified poor sleepers with affective symptoms.
(11) The team of regional advisers and rough sleeper and youth specialists which have provided councils with expert guidance on meeting statutory homelessness duties since 2007 will be disbanded just as the bedroom tax comes in.
(12) "In any strike, Iran would likely retaliate against US soldiers and assets in Afghanistan and Iraq, and might activate sleeper cells to launch al-Qaida-like attacks against the US homeland and in Europe."
(13) Pull it off and the sport could become a sleeper hit of the summer – as well as making its leading men and lady genuine box office.
(14) As a test of the hypothesis that consistent short sleepers tend to be less reflective and more conformist in their thinking than long sleepers, the I-E scale scores of 15 short and 15 long sleepers were compared.
(15) According to the differential decay interpretation, a sleeper effect occurs when message and discounting cue have opposite and near-equal immediate impacts that are not well-integrated in memory.
(16) She acquired British nationality through marriage before travelling to the US to join a network of sleeper agents.
(17) 13 chronic primary insomniacs and a matched group of normal sleepers were studied in terms of their level of novelty-seeking, ability to fantasize, and cognitive rumination.
(18) Two groups of good and poor sleepers were compared (15 subjects aged 22-26 years in each).
(19) Young, H. Wallberg-Henriksson, M. D. Sleeper, and J. O. Holloszy.
(20) Clinical and clinimetric properties of the PSQI were assessed over an 18-month period with "good" sleepers (healthy subjects, n = 52) and "poor" sleepers (depressed patients, n = 54; sleep-disorder patients, n = 62).