(1) [3H]cyclohexyladenosine (CHA) and [3H]PN200-110 were used to label muscarinic and adenosine A1 receptors and L-type calcium channels, respectively.
(2) Since ADO is a metabolic substrate and a nonselective receptor agonist, while CHA is A1-selective and a poor substrate for cellular uptake, neither A2 activation nor cellular uptake altered expression of the A1 effect of exogenous ADO.
(3) R-PIA, CHA and NECA inhibited contraction in both preparations.
(4) In contrast to the relative consistency of the patterns of 3H-CHA binding in these species, 5'-nucleotidase exhibited wide variations in both the absolute amount of activity and its localization.
(5) Concomitant measurement of [3H]-CHA binding in the mesencephalic reticular formation was also carried out in order to explore the neurochemical basis of the development of tolerance.
(6) For aortic relaxation the analogues exhibited the following rank order of potency: NECA greater than adenosine greater than 2-CA greater than R-PIA greater than CHA.
(7) Regulation of c-fos protooncogene activity in rat embryonal fibroblasts (REF), E1Aad5-immortalized REF cells, and E1Aad5 + cHa-ras transformed REF cells has been investigated.
(8) Although more studies are needed, a recent report of potential utilization of nonstimulated oocytes for donor programs as well as IVF-cryopreservation was a promising new development (Cha et al.
(9) 3H-CHA and 3H-NECA binding sites are concentrated in layers 1-3 and upper layer 5 in the visual cortex of adult cats.
(10) In this paper, CDDP-CHA tried to apply for experimental bone and soft tissue sarcoma.
(11) The effect of toxin on adenosine receptors was also evaluated by measuring binding of the adenosine agonist cyclohexyladenosine (CHA).
(12) "All those vuvuzuelas must be interfering with Cha Bum-Kun's ability to remote control his robot creation - er, son - Cha Du-ri," suggests Angela K, a South Korean expat in the US.
(13) The R(-)- and S(+)-enantiomers of N6-(2-phenylisopropyl)adenosine (R-PIA and S-PIA respectively), N6-cyclohexyladenosine (CHA) and 2-chloroadenosine (CADO) caused contractions at low concentrations (0.05-2.0 microM), whereas at higher concentrations, relaxation resulted.
(14) Circular harmonic averaging (CHA), a novel, reference-independent averaging method developed by W. Kunath and H. Sack-Kongehl [1989) Ultramicroscopy 27:171-184) allows analyzing images of single molecules of the receptor in its native membrane-bound state.
(15) An unexpected finding was that R-PIA, 2-CA and CHA all induced contractions at concentrations lower than were required for relaxation, giving a biphasic dose-response curve.
(16) Concentrations to achieve half-maximum responses were 92.5 nM for 2-ClAdo, 39 nM for CHA, and 107 nM for NECA.
(17) Moreover, the addition of guanylyl-5'-imidodiphosphate, a GTP analogue, to the incubation medium reduced CHA binding by the same order of magnitude whether rats were given saline or bicuculline, suggesting that additional adenosine A1 receptors are also functionally linked to G proteins.
(18) Hippocampi from theophylline-treated animals showed a significantly greater number of [3H]CHA binding sites (apparent Bmax; 125% of control, P less than 0.05), without a significant change in binding affinity, and were more sensitive than controls to the inhibitory effects of adenosine on the population spike response.
(19) Both genes were shown to be present in haploid embryos and have been isolated from a genomic library, the exons and deduced amino acid sequences of which are presented here (salmon CHA and CHB).
(20) Accordingly, the peak in adenosine receptor binding, using (-)[125I]iodo-N6-hydroxyphenyl-isopropyladenosine as the radioligand, coincided with CHA-inhibitable adenylate cyclase activity.
Tea
Definition:
(n.) The prepared leaves of a shrub, or small tree (Thea, / Camellia, Chinensis). The shrub is a native of China, but has been introduced to some extent into some other countries.
(n.) A decoction or infusion of tea leaves in boiling water; as, tea is a common beverage.
(n.) Any infusion or decoction, especially when made of the dried leaves of plants; as, sage tea; chamomile tea; catnip tea.
(n.) The evening meal, at which tea is usually served; supper.
(v. i.) To take or drink tea.
Example Sentences:
(1) The outward currents are sensitive to TEA and their reversal potentials differ.
(2) As prolongation of the action potential by TEA facilitates preferentially the hormone release evoked by low (ineffective) frequencies, it is suggested that a frequency-dependent broadening of action potentials which reportedly occurs on neurosecretory neurones may play an important role in the frequency-dependent facilitation of hormone release from the rat neurohypophysis.
(3) In contrast, the fast block by internal TEA+ appeared virtually independent of voltage.
(4) In conclusion, block of inhibitory innervation, and induction of electrical slow waves as a control mechanism for phasic contractile activity, seems to require blockade of an aminacrine- but not TEA-sensitive potassium conductance.
(5) And it means the Foreign Office dealing with those in the Middle East and North Africa who are on the side of democracy and human rights, not sitting down to tea with torturers.
(6) The Tea Party movement has turned climate denial into a litmus test of conservative credentials – and that has made climate change one of the most sharp divisions between Obama and Romney.
(7) The addition of chlorhexidine and saliva increased staining when used with tea.
(8) Results with the model strengthen the hypothesis that tetraethylammonium (TEA) acts on both the maximum potassium conductance (gK) and the mechanism of sodium conductance inactivation (Tauh) to lengthen the action potential as observed on the Ranvier node (fig.
(9) Sources said that when Mitchell toured the Commons tea rooms on Wednesday and Thursday, he was taken aback by the opposition to him staying put, despite Cameron's support.
(10) The Vitter amendment is popular with the Tea Party, which takes it to be an accountability measure.
(11) You literally never see that at political rallies, though obviously at Tea Party ones they are there all the time."
(12) The acidosis-saving property of TEA is favorable for the ischemic heart.
(13) The council offered him a tea urn | Frances Ryan Read more Government attempts to decrease the disproportionately high levels of unemployment among disabled people have had little impact, the report notes, while notorious “fit-for-work” tests were riven with flaws.
(14) 8.04pm BST First challenge for the remaining seven is the tea loaf.
(15) While you can buy commercial formulations, I have always found that tap water, a cup of strong black tea, and some lemon juice provide enough nutrients for a lovely fermentation.
(16) Up-and-coming Tea Party favourite Ted Cruz issued a similar statementon Friday after the wave of disclosures, saying he would work with "colleagues in the Senate who share my concerns to ensure that we have all the facts about these surveillance programs".
(17) Litvinenko died aged 43 after drinking tea laced with radioactive polonium-210 at a meeting with two Russian men at the Millennium hotel in Grosvenor Square, London, in November 2006.
(18) The Norwegian researchers looked at all the sources of caffeine ingested by the pregnant women, including coffee, tea and fizzy drinks, along with cakes and desserts containing cocoa (which has lots of caffeine).
(19) Currents through both the voltage-activated potassium channels, IK,V, and the calcium-activated potassium channels, IK,Ca, can be blocked by the membrane-impermeant K channel blocker tetraethylammonium (TEA).
(20) Replacement of sodium by tetraethylammonium (TEA) did not reduce the slow inward tail current, nor change its reversal potential.