(n.) An invitation to engage in a contest or controversy of any kind; a defiance; specifically, a summons to fight a duel; also, the letter or message conveying the summons.
(n.) The act of a sentry in halting any one who appears at his post, and demanding the countersign.
(n.) A claim or demand.
(n.) The opening and crying of hounds at first finding the scent of their game.
(n.) An exception to a juror or to a member of a court martial, coupled with a demand that he should be held incompetent to act; the claim of a party that a certain person or persons shall not sit in trial upon him or his cause.
(n.) An exception to a person as not legally qualified to vote. The challenge must be made when the ballot is offered.
(n.) To call to a contest of any kind; to call to answer; to defy.
(n.) To call, invite, or summon to answer for an offense by personal combat.
(n.) To claim as due; to demand as a right.
(n.) To censure; to blame.
(n.) To question or demand the countersign from (one who attempts to pass the lines); as, the sentinel challenged us, with "Who comes there?"
(n.) To take exception to; question; as, to challenge the accuracy of a statement or of a quotation.
(n.) To object to or take exception to, as to a juror, or member of a court.
(n.) To object to the reception of the vote of, as on the ground that the person in not qualified as a voter.
(v. i.) To assert a right; to claim a place.
Example Sentences:
(1) Bronchial challenge caused an immediate asthmatic response.
(2) When chimeric animals were subjected to a lethal challenge of endotoxin, their response was markedly altered by the transferred lymphoid cells.
(3) This frees the student to experience the excitement and challenge of learning and the joy of helping people.
(4) The degree of increase in Meth responsiveness elicited by the initial provocation is a major factor in determining the airway response to a subsequent HS challenge.
(5) Intranasal challenge of allergic subjects with the allergen to which they are sensitive rapidly produces sneezing, rhinorrhea, and airway obstruction.
(6) Matthias Müller, VW’s chief executive, said: “In light of the wide range of challenges we are currently facing, we are satisfied overall with the start we have made to what will undoubtedly be a demanding fiscal year 2016.
(7) In 1935, Einstein challenged the prevailing interpretation of quantum theory.
(8) A shrinking populace is perhaps a greater challenge than any problems with Russia.
(9) Intraperitoneal injection of indomethacin to pretreated animals resulted in increased levels of IL-1 and TNF and decreased levels of PGE2 following challenge with E. coli.
(10) Think of Nelson Mandela – there is a determination, an unwillingness to bend in the face of challenges, that earns you respect and makes people look to you for guidance.
(11) The children's pulse, pulse rate variability, and blood pressure were then measured at rest and during a challenging situation.
(12) At first it looked as though the winger might have shown too much of the ball to the defence, yet he managed to gain a crucial last touch to nudge it past Phil Jones and into the path of Jerome, who slipped Chris Smalling’s attempt at a covering tackle and held off Michael Carrick’s challenge to place a shot past an exposed De Gea.
(13) The results support the notion that mediator lymphocytes circulate in tumor immunized rats in a noncytotoxic state, specifically recognize tumor cells at a challenge site, and mediate induction of effector cells locally.
(14) The role of blood acetylcholinesterase in moderating the effects of organophosphate challenge in rats was tested.
(15) In the first trial to investigate the effect of tick control, significant improvements in liveweight gain (LWG) occurred only in periods of medium to high challenge with adult Amblyomma variegatum.
(16) The SNT and the I-ELISA indicated that the pigs responded to vaccination and challenge.
(17) When caffeine evokes a contraction, and only then, crayfish muscle fibers become refractory to a second challenge with caffeine for up to 20 min in the standard saline (5 mM K(o)).
(18) This observation seriously challenges the hypothesis that SCE cancellation results as a consequence of persistence of the lesions induced by these agents.
(19) Injection of about four ImD 50 of vaccine intracerebrally produced a local immunity, resulting in an immediate kill of challenge organisms given 14 days later.
(20) There was no correlation between anti-TNP-precipitating antibody titer after sensitization and the ability to respond to challenge by hapten-heterologous carrier.
On
Definition:
(prep.) In continuance; without interruption or ceasing; as, sleep on, take your ease; say on; sing on.
(prep.) The general signification of on is situation, motion, or condition with respect to contact or support beneath
(prep.) At, or in contact with, the surface or upper part of a thing, and supported by it; placed or lying in contact with the surface; as, the book lies on the table, which stands on the floor of a house on an island.
(prep.) To or against the surface of; -- used to indicate the motion of a thing as coming or falling to the surface of another; as, rain falls on the earth.
(prep.) Denoting performance or action by contact with the surface, upper part, or outside of anything; hence, by means of; with; as, to play on a violin or piano. Hence, figuratively, to work on one's feelings; to make an impression on the mind.
(prep.) At or near; adjacent to; -- indicating situation, place, or position; as, on the one hand, on the other hand; the fleet is on the American coast.
(prep.) In addition to; besides; -- indicating multiplication or succession in a series; as, heaps on heaps; mischief on mischief; loss on loss; thought on thought.
(prep.) Indicating dependence or reliance; with confidence in; as, to depend on a person for assistance; to rely on; hence, indicating the ground or support of anything; as, he will promise on certain conditions; to bet on a horse.
(prep.) At or in the time of; during; as, on Sunday we abstain from labor. See At (synonym).
(prep.) At the time of, conveying some notion of cause or motive; as, on public occasions, the officers appear in full dress or uniform. Hence, in consequence of, or following; as, on the ratification of the treaty, the armies were disbanded.
(prep.) Toward; for; -- indicating the object of some passion; as, have pity or compassion on him.
(prep.) At the peril of, or for the safety of.
(prep.) By virtue of; with the pledge of; -- denoting a pledge or engagement, and put before the thing pledged; as, he affirmed or promised on his word, or on his honor.
(prep.) To the account of; -- denoting imprecation or invocation, or coming to, falling, or resting upon; as, on us be all the blame; a curse on him.
(prep.) In reference or relation to; as, on our part expect punctuality; a satire on society.
(prep.) Of.
(prep.) Occupied with; in the performance of; as, only three officers are on duty; on a journey.
(prep.) In the service of; connected with; of the number of; as, he is on a newspaper; on a committee.
(prep.) Forward, in progression; onward; -- usually with a verb of motion; as, move on; go on.
(prep.) Forward, in succession; as, from father to son, from the son to the grandson, and so on.
(prep.) Adhering; not off; as in the phrase, "He is neither on nor off," that is, he is not steady, he is irresolute.
(prep.) Attached to the body, as clothing or ornament, or for use.
(prep.) In progress; proceeding; as, a game is on.