(n.) An invitation to engage in a contest or controversy of any kind; a defiance; specifically, a summons to fight a duel; also, the letter or message conveying the summons.
(n.) The act of a sentry in halting any one who appears at his post, and demanding the countersign.
(n.) A claim or demand.
(n.) The opening and crying of hounds at first finding the scent of their game.
(n.) An exception to a juror or to a member of a court martial, coupled with a demand that he should be held incompetent to act; the claim of a party that a certain person or persons shall not sit in trial upon him or his cause.
(n.) An exception to a person as not legally qualified to vote. The challenge must be made when the ballot is offered.
(n.) To call to a contest of any kind; to call to answer; to defy.
(n.) To call, invite, or summon to answer for an offense by personal combat.
(n.) To claim as due; to demand as a right.
(n.) To censure; to blame.
(n.) To question or demand the countersign from (one who attempts to pass the lines); as, the sentinel challenged us, with "Who comes there?"
(n.) To take exception to; question; as, to challenge the accuracy of a statement or of a quotation.
(n.) To object to or take exception to, as to a juror, or member of a court.
(n.) To object to the reception of the vote of, as on the ground that the person in not qualified as a voter.
(v. i.) To assert a right; to claim a place.
Example Sentences:
(1) Bronchial challenge caused an immediate asthmatic response.
(2) When chimeric animals were subjected to a lethal challenge of endotoxin, their response was markedly altered by the transferred lymphoid cells.
(3) This frees the student to experience the excitement and challenge of learning and the joy of helping people.
(4) The degree of increase in Meth responsiveness elicited by the initial provocation is a major factor in determining the airway response to a subsequent HS challenge.
(5) Intranasal challenge of allergic subjects with the allergen to which they are sensitive rapidly produces sneezing, rhinorrhea, and airway obstruction.
(6) Matthias Müller, VW’s chief executive, said: “In light of the wide range of challenges we are currently facing, we are satisfied overall with the start we have made to what will undoubtedly be a demanding fiscal year 2016.
(7) In 1935, Einstein challenged the prevailing interpretation of quantum theory.
(8) A shrinking populace is perhaps a greater challenge than any problems with Russia.
(9) Intraperitoneal injection of indomethacin to pretreated animals resulted in increased levels of IL-1 and TNF and decreased levels of PGE2 following challenge with E. coli.
(10) Think of Nelson Mandela – there is a determination, an unwillingness to bend in the face of challenges, that earns you respect and makes people look to you for guidance.
(11) The children's pulse, pulse rate variability, and blood pressure were then measured at rest and during a challenging situation.
(12) At first it looked as though the winger might have shown too much of the ball to the defence, yet he managed to gain a crucial last touch to nudge it past Phil Jones and into the path of Jerome, who slipped Chris Smalling’s attempt at a covering tackle and held off Michael Carrick’s challenge to place a shot past an exposed De Gea.
(13) The results support the notion that mediator lymphocytes circulate in tumor immunized rats in a noncytotoxic state, specifically recognize tumor cells at a challenge site, and mediate induction of effector cells locally.
(14) The role of blood acetylcholinesterase in moderating the effects of organophosphate challenge in rats was tested.
(15) In the first trial to investigate the effect of tick control, significant improvements in liveweight gain (LWG) occurred only in periods of medium to high challenge with adult Amblyomma variegatum.
(16) The SNT and the I-ELISA indicated that the pigs responded to vaccination and challenge.
(17) When caffeine evokes a contraction, and only then, crayfish muscle fibers become refractory to a second challenge with caffeine for up to 20 min in the standard saline (5 mM K(o)).
(18) This observation seriously challenges the hypothesis that SCE cancellation results as a consequence of persistence of the lesions induced by these agents.
(19) Injection of about four ImD 50 of vaccine intracerebrally produced a local immunity, resulting in an immediate kill of challenge organisms given 14 days later.
(20) There was no correlation between anti-TNP-precipitating antibody titer after sensitization and the ability to respond to challenge by hapten-heterologous carrier.
Rubicon
Definition:
(n.) A small river which separated Italy from Cisalpine Gaul, the province alloted to Julius Caesar.
Example Sentences:
(1) The Mail branded the deal "a grim day for all who value freedom" and, like the Times, accused David Cameron of crossing the Rubicon and threatening press freedom for the first time since newspapers were licensed in the 17th century.
(2) He said he accepted the principle of independent regulation, arguing that the current system "is badly broken and it has let down victims" – but insisted that any proposal to underpin a new regulator with a law, as proposed by Leveson, would "cross the Rubicon" of state intervention into press freedom.
(3) On 1 August Palmer told Guardian Australia his senators were firmly against any Medicare co-payment on the basis it “crosses the Rubicon” on access to free healthcare.
(4) The prime minister has said a press law would be "crossing the Rubicon" but it is understood that a "dab of statute" which would underpin a royal charter and ban the privy council from amending any charter would be acceptable to Associated, News International and the Telegraph.
(5) Glasenberg, says one person who knows how much he anguished over the decision to take Glencore public, is well aware that he "has crossed the Rubicon".
(6) He believes the prime minister's main reservation, his "Rubicon", has been addressed.
(7) It is the historian who has decided for his own reasons that Caesar’s crossing of that petty stream, the Rubicon, is a fact of history, whereas the crossing of the Rubicon by millions of other people before or since interests nobody at all.” The speeches we believe to be most decisive can come only from those speeches we have heard about.
(8) He was taken to Govan police station, the base for Operation Rubicon, the inquiry set up to investigate alleged perjury at the trial.
(9) In 1986 he made perhaps his biggest blunder, his infamous "Rubicon" speech.
(10) Tony Yates, a professor of economics at Birmingham University and a former Bank insider, says: “Once they’ve crossed the Rubicon of doing it, what would be to stop the political clamour for using QE to pay for something else?
(11) I have three concerns: First, a change in the law to permit assisted suicide would cross a fundamental legal and ethical Rubicon.
(12) Ehab Badawy claims that Egypt has "crossed the democratic rubicon" in the recent presidential election ( Letters, 3 June ).
(13) iPad Great Little War Game 2 (£1.99) Developer Rubicon Development has won a wide following with its little and big war games.
(14) Palmer said Australia’s health system was much more efficient than the one in the US, and the PUP senators were united in their opposition to any Medicare co-payment on the basis it “crosses the Rubicon” on access to free healthcare.
(15) We will take deep breaths and cross the Rubicon with you, or at least the Firth of Forth.
(16) It may be that [the government has] crossed a Rubicon and decided that [mass] data-gathering exercises are something [it] should try out – but you can't have it under the existing regime."
(17) Diluted soil samples (Rubicon fine sand, Entic Haplorthods [pH 5.9]) were plated on soil extract-glucose agar containing radioactive 65Zn.
(18) We’ve made it into the final and crossed the Rubicon.
(19) He was not, he said, willing to pass that Rubicon .
(20) What caught the headlines was Cameron's call for an in-out referendum on renegotiated terms – apparently a Rubicon.