(n.) An invitation to engage in a contest or controversy of any kind; a defiance; specifically, a summons to fight a duel; also, the letter or message conveying the summons.
(n.) The act of a sentry in halting any one who appears at his post, and demanding the countersign.
(n.) A claim or demand.
(n.) The opening and crying of hounds at first finding the scent of their game.
(n.) An exception to a juror or to a member of a court martial, coupled with a demand that he should be held incompetent to act; the claim of a party that a certain person or persons shall not sit in trial upon him or his cause.
(n.) An exception to a person as not legally qualified to vote. The challenge must be made when the ballot is offered.
(n.) To call to a contest of any kind; to call to answer; to defy.
(n.) To call, invite, or summon to answer for an offense by personal combat.
(n.) To claim as due; to demand as a right.
(n.) To censure; to blame.
(n.) To question or demand the countersign from (one who attempts to pass the lines); as, the sentinel challenged us, with "Who comes there?"
(n.) To take exception to; question; as, to challenge the accuracy of a statement or of a quotation.
(n.) To object to or take exception to, as to a juror, or member of a court.
(n.) To object to the reception of the vote of, as on the ground that the person in not qualified as a voter.
(v. i.) To assert a right; to claim a place.
Example Sentences:
(1) Bronchial challenge caused an immediate asthmatic response.
(2) When chimeric animals were subjected to a lethal challenge of endotoxin, their response was markedly altered by the transferred lymphoid cells.
(3) This frees the student to experience the excitement and challenge of learning and the joy of helping people.
(4) The degree of increase in Meth responsiveness elicited by the initial provocation is a major factor in determining the airway response to a subsequent HS challenge.
(5) Intranasal challenge of allergic subjects with the allergen to which they are sensitive rapidly produces sneezing, rhinorrhea, and airway obstruction.
(6) Matthias Müller, VW’s chief executive, said: “In light of the wide range of challenges we are currently facing, we are satisfied overall with the start we have made to what will undoubtedly be a demanding fiscal year 2016.
(7) In 1935, Einstein challenged the prevailing interpretation of quantum theory.
(8) A shrinking populace is perhaps a greater challenge than any problems with Russia.
(9) Intraperitoneal injection of indomethacin to pretreated animals resulted in increased levels of IL-1 and TNF and decreased levels of PGE2 following challenge with E. coli.
(10) Think of Nelson Mandela – there is a determination, an unwillingness to bend in the face of challenges, that earns you respect and makes people look to you for guidance.
(11) The children's pulse, pulse rate variability, and blood pressure were then measured at rest and during a challenging situation.
(12) At first it looked as though the winger might have shown too much of the ball to the defence, yet he managed to gain a crucial last touch to nudge it past Phil Jones and into the path of Jerome, who slipped Chris Smalling’s attempt at a covering tackle and held off Michael Carrick’s challenge to place a shot past an exposed De Gea.
(13) The results support the notion that mediator lymphocytes circulate in tumor immunized rats in a noncytotoxic state, specifically recognize tumor cells at a challenge site, and mediate induction of effector cells locally.
(14) The role of blood acetylcholinesterase in moderating the effects of organophosphate challenge in rats was tested.
(15) In the first trial to investigate the effect of tick control, significant improvements in liveweight gain (LWG) occurred only in periods of medium to high challenge with adult Amblyomma variegatum.
(16) The SNT and the I-ELISA indicated that the pigs responded to vaccination and challenge.
(17) When caffeine evokes a contraction, and only then, crayfish muscle fibers become refractory to a second challenge with caffeine for up to 20 min in the standard saline (5 mM K(o)).
(18) This observation seriously challenges the hypothesis that SCE cancellation results as a consequence of persistence of the lesions induced by these agents.
(19) Injection of about four ImD 50 of vaccine intracerebrally produced a local immunity, resulting in an immediate kill of challenge organisms given 14 days later.
(20) There was no correlation between anti-TNP-precipitating antibody titer after sensitization and the ability to respond to challenge by hapten-heterologous carrier.
Stake
Definition:
(v. t.) To fasten, support, or defend with stakes; as, to stake vines or plants.
(v. t.) A piece of wood, usually long and slender, pointed at one end so as to be easily driven into the ground as a support or stay; as, a stake to support vines, fences, hedges, etc.
(v. t.) A stick inserted upright in a lop, eye, or mortise, at the side or end of a cart, a flat car, or the like, to prevent goods from falling off.
(v. t.) The piece of timber to which a martyr was affixed to be burned; hence, martyrdom by fire.
(v. t.) A small anvil usually furnished with a tang to enter a hole in a bench top, -- used by tinsmiths, blacksmiths, etc., for light work, punching upon, etc.
(v. t.) That which is laid down as a wager; that which is staked or hazarded; a pledge.
(v. t.) To mark the limits of by stakes; -- with out; as, to stake out land; to stake out a new road.
(v. t.) To put at hazard upon the issue of competition, or upon a future contingency; to wager; to pledge.
(v. t.) To pierce or wound with a stake.
Example Sentences:
(1) It is not clear whether Sports Direct, which has a history of taking strategic stakes in related companies including Debenhams and JD Sports, will now make a bid.
(2) Even so, the release of the first-half figures could help clear the way for the chancellor, George Osborne, to start selling off the taxpayer’s 79% stake in the bank, a legacy of the institution’s 2008 bailout.
(3) The Press Association tots up a total of £26bn in asset sales last year – including the state’s Eurostar stake, 30% of the Royal Mail and a slice of Lloyds.
(4) Shares in the bank have fallen more than 30% since Britain voted to leave the EU and the share closed on Monday at 167p, well below the 502p average price at which taxpayers bought their stake in the bank.
(5) Cobra collapsed into administration in 2009 after which Lord Bilimoria was criticised for using a “pre-pack” deal to buy back a stake in the firm.
(6) Republicans remain wary of a contentious debate on the divisive issue, which could anger their core voters and undercut potential electoral gains in the November elections when control of Congress will be at stake.
(7) But Mr Bolloré, with a 29% stake in Aegis, vowed to keep calling shareholder meetings until he gets his way.
(8) Xenophon’s letter says if State Grid is also allowed to own a huge stake in Ausgrid it raises serious questions about market dominance.
(9) Rawlins bought a stake in Stoke City in 2000, where he'd been a season ticket-holder from the age of five, after selling off his IT consultancy company and joined the board.
(10) They also point to her involvement, between 1999 and 2005, with Computer Associates-Jinchen, a joint venture between an American tech company and a Chinese firm in which China’s ministry of public security reportedly held a 20% stake.
(11) That stake in eight Indonesian coal mines represents 1GT of future carbon dioxide emissions, more than Germany’s annual output.
(12) Buffett’s fortune was briefly boosted by another $5.7bn purely on his personal stake in Kraft Heinz, whose shares rose 10%, while Unilever shares rose 13.4% to a record high.
(13) Despite its 25% stake, BP said it would be wrong to assume that it would obtain a quarter of the expected $100bn worth of revenues.
(14) Most of the money, says WDM, was used to buy shares in Bumi , the troubled London-listed firm co-founded by financier Nat Rothschild that owns large stakes in some of the biggest mining projects in East Kalimantan.
(15) They will not be able to vote out the non-execs because Ashley has that vast stake, but there are occasions when principles are important and this September's AGM will be one of them.
(16) Shell has pulled out of renewables: it retains a small stake in biofuels development, but the company's offshore wind business is no more.
(17) Rupert Murdoch has a battle on his hands to win over leading shareholders in BSkyB, who scent the opportunity for a high-stakes game of brinkmanship and are pushing for a premium price of well over £10bn for full control of the pay-television company.
(18) The future of our children, grandchildren and beyond is at stake.
(19) To maintain its 30% stake the Co-op would need to stump up another £120m, increasing its already high debt levels.
(20) Two years later, the privately held Lovefilm acquired Amazon's UK and German movie rental business, with the online retail giant taking a stake in the business as part of the deal.