(n.) An invitation to engage in a contest or controversy of any kind; a defiance; specifically, a summons to fight a duel; also, the letter or message conveying the summons.
(n.) The act of a sentry in halting any one who appears at his post, and demanding the countersign.
(n.) A claim or demand.
(n.) The opening and crying of hounds at first finding the scent of their game.
(n.) An exception to a juror or to a member of a court martial, coupled with a demand that he should be held incompetent to act; the claim of a party that a certain person or persons shall not sit in trial upon him or his cause.
(n.) An exception to a person as not legally qualified to vote. The challenge must be made when the ballot is offered.
(n.) To call to a contest of any kind; to call to answer; to defy.
(n.) To call, invite, or summon to answer for an offense by personal combat.
(n.) To claim as due; to demand as a right.
(n.) To censure; to blame.
(n.) To question or demand the countersign from (one who attempts to pass the lines); as, the sentinel challenged us, with "Who comes there?"
(n.) To take exception to; question; as, to challenge the accuracy of a statement or of a quotation.
(n.) To object to or take exception to, as to a juror, or member of a court.
(n.) To object to the reception of the vote of, as on the ground that the person in not qualified as a voter.
(v. i.) To assert a right; to claim a place.
Example Sentences:
(1) Bronchial challenge caused an immediate asthmatic response.
(2) When chimeric animals were subjected to a lethal challenge of endotoxin, their response was markedly altered by the transferred lymphoid cells.
(3) This frees the student to experience the excitement and challenge of learning and the joy of helping people.
(4) The degree of increase in Meth responsiveness elicited by the initial provocation is a major factor in determining the airway response to a subsequent HS challenge.
(5) Intranasal challenge of allergic subjects with the allergen to which they are sensitive rapidly produces sneezing, rhinorrhea, and airway obstruction.
(6) Matthias Müller, VW’s chief executive, said: “In light of the wide range of challenges we are currently facing, we are satisfied overall with the start we have made to what will undoubtedly be a demanding fiscal year 2016.
(7) In 1935, Einstein challenged the prevailing interpretation of quantum theory.
(8) A shrinking populace is perhaps a greater challenge than any problems with Russia.
(9) Intraperitoneal injection of indomethacin to pretreated animals resulted in increased levels of IL-1 and TNF and decreased levels of PGE2 following challenge with E. coli.
(10) Think of Nelson Mandela – there is a determination, an unwillingness to bend in the face of challenges, that earns you respect and makes people look to you for guidance.
(11) The children's pulse, pulse rate variability, and blood pressure were then measured at rest and during a challenging situation.
(12) At first it looked as though the winger might have shown too much of the ball to the defence, yet he managed to gain a crucial last touch to nudge it past Phil Jones and into the path of Jerome, who slipped Chris Smalling’s attempt at a covering tackle and held off Michael Carrick’s challenge to place a shot past an exposed De Gea.
(13) The results support the notion that mediator lymphocytes circulate in tumor immunized rats in a noncytotoxic state, specifically recognize tumor cells at a challenge site, and mediate induction of effector cells locally.
(14) The role of blood acetylcholinesterase in moderating the effects of organophosphate challenge in rats was tested.
(15) In the first trial to investigate the effect of tick control, significant improvements in liveweight gain (LWG) occurred only in periods of medium to high challenge with adult Amblyomma variegatum.
(16) The SNT and the I-ELISA indicated that the pigs responded to vaccination and challenge.
(17) When caffeine evokes a contraction, and only then, crayfish muscle fibers become refractory to a second challenge with caffeine for up to 20 min in the standard saline (5 mM K(o)).
(18) This observation seriously challenges the hypothesis that SCE cancellation results as a consequence of persistence of the lesions induced by these agents.
(19) Injection of about four ImD 50 of vaccine intracerebrally produced a local immunity, resulting in an immediate kill of challenge organisms given 14 days later.
(20) There was no correlation between anti-TNP-precipitating antibody titer after sensitization and the ability to respond to challenge by hapten-heterologous carrier.
Tackle
Definition:
(n.) Apparatus for raising or lowering heavy weights, consisting of a rope and pulley blocks; sometimes, the rope and attachments, as distinct from the block.
(n.) Any instruments of action; an apparatus by which an object is moved or operated; gear; as, fishing tackle, hunting tackle; formerly, specifically, weapons.
(n.) The rigging and apparatus of a ship; also, any purchase where more than one block is used.
(n.) To supply with tackle.
(n.) To fasten or attach, as with a tackle; to harness; as, to tackle a horse into a coach or wagon.
(n.) To seize; to lay hold of; to grapple; as, a wrestler tackles his antagonist; a dog tackles the game.
(n.) To begin to deal with; as, to tackle the problem.
Example Sentences:
(1) It has announced a four-stage programme of reforms that will tackle most of these stubborn and longstanding problems, including Cinderella issues such as how energy companies treat their small business customers.
(2) Considerate touches includes the free use of cruiser bicycles (the best method of tackling the Palm Springs main drag), home-baked cookies … and if you'd like to get married, ask the manager: he's a minister.
(3) In a newspaper interview last month, Shapps said the BBC needed to tackle what he said was a culture of secrecy, waste and unbalanced reporting if it hoped to retain the full £3.6bn raised by the licence fee after the current Royal Charter expires in 2016.
(4) At first it looked as though the winger might have shown too much of the ball to the defence, yet he managed to gain a crucial last touch to nudge it past Phil Jones and into the path of Jerome, who slipped Chris Smalling’s attempt at a covering tackle and held off Michael Carrick’s challenge to place a shot past an exposed De Gea.
(5) So fourth, we must tackle the issue of a relatively large number of officers kept on restricted duties, on full pay.
(6) Chadwick felt that Customs and Trading Standards needed to continue their war on illegal tobacco – if not, efforts to tackle smoking could be undermined.
(7) Stray bottles were thrown over the barriers towards officers to cheers and chants of: “Shame on you, we’re human too.” The Met deployed what it described as a “significant policing operation”, including drafting in thousands of extra officers to tackle expected unrest, after previous events ended in arrests and clashes with police across the centre of the capital.
(8) Terrorist groups need to be tackled at root, interdicting flows of weapons and finance, exposing the shallowness of their claims, channelling their followers into democratic politics.
(9) She said the rise in fees was not part of the effort to tackle the deficit, but was instead about Clegg "going along with Tory plans to shove the cost of higher education on to students and their families".
(10) A fortnight ago the two countries signed a US$27 million deal to tackle deforestation on the island of Sumatra - a key problem in Indonesia where 80 per cent of emissions come from deforestation, both by legal and illegal loggers.
(11) There, the US Joint Commission, an independent, non-profit organisation that accredits healthcare organisations and programmes has issued a standard on “behaviours that undermine a culture of safety” to tackle “intimidating and disruptive behaviour at work”.
(12) As corruption consistently ranks as a top concern for Spaniards, second only to unemployment, and with an eye on upcoming municipal and regional elections in the spring, Spain’s political parties have been keen to appear as if they are tackling the issue.
(13) But the drugs chief, Julio Calzada, is blunt: " For 50 years, we have tried to tackle the drug problem with only one tool – penalisation – and that has failed .
(14) 1-1 2.15am GMT 48 mins Giles Barnes is down again, turning his ankle under a challenge (but not actually touched by the tackle).
(15) Many alternative, more reliable sources of public finance are out there – a tax on financial transactions would provide billions of dollars of new money for developing countries to tackle climate change head on."
(16) Labour and, sotto voce, some Lib Dems, counter that Clegg did not need to cede this much ground – there is no clear evidence that the markets will impose higher interest rates if the deficit is not tackled more quickly than Labour planned.
(17) In a single letter in February 2005, Charles urged a badger cull to prevent the spread of bovine tuberculosis – damning opponents to the cull as “intellectually dishonest”; lobbied for his preferred person to be appointed to crack down on the mistreatment of farmers by supermarkets; proposed his own aide to brief Downing Street on the design of new hospitals; and urged Blair to tackle an EU directive limiting the use of herbal alternative medicines in the UK.
(18) Shelby Quast, of Equality Now, said the gathering could be a “tipping point” and act as a catalyst for change, so that girls in the US could finally be protected: “It’s the first time that members of the government are coming around the table to meet with civil society, survivors and members of the diaspora – this is the first step towards putting together a comprehensive action plan to tackling FGM.” Campaigners are calling for the government to look at practical ways that FGM could be wiped out in the United States – such as engaging with paediatricians and other doctors, immigration officers and visa offices.
(19) Tackling deforestation, which contributes up to 20% of all greenhouse gas emissions, took a step forward, with the UK, along with Japan, Norway, America, France and Australia, agreeing that by 2010 a total of $3.5bn would be spent on saving trees.
(20) The home secretary, Theresa May, will attend a summit in Washington on tackling violent extremism, called by Barack Obama after the Charlie Hebdo murders in Paris.