(n.) The hollow bed where a stream of water runs or may run.
(n.) The deeper part of a river, harbor, strait, etc., where the main current flows, or which affords the best and safest passage for vessels.
(n.) A strait, or narrow sea, between two portions of lands; as, the British Channel.
(n.) That through which anything passes; means of passing, conveying, or transmitting; as, the news was conveyed to us by different channels.
(n.) A gutter; a groove, as in a fluted column.
(n.) Flat ledges of heavy plank bolted edgewise to the outside of a vessel, to increase the spread of the shrouds and carry them clear of the bulwarks.
(v. t.) To form a channel in; to cut or wear a channel or channels in; to groove.
(v. t.) To course through or over, as in a channel.
Example Sentences:
(1) These channels may, at least in some cases, be responsible for the generation of pacemaker depolarizations, thereby regulating firing behaviour.
(2) The influence of the various concepts for the induction of lateral structure formation in lipid membranes on integral functional units like ionophores is demonstrated by analysing the single channel current fluctuations of gramicidin in bimolecular lipid membranes.
(3) RNAs encoding a wild-type (RBK1) and a mutant (RBK1(Y379V,V381T); RBK1*) subunit of voltage-dependent potassium channels were injected into Xenopus oocytes.
(4) The dramas are part of the BBC2 controller Janice Hadlow's plans for her "unashamedly intelligent" channel over the coming months.
(5) This was unlike the action of the calcium channel blocker, cadmium, which reduced the calcium action potential and the a.h.p.
(6) Circuitry has been developed to feed the output of an ear densitogram pickup into one channel of a two-channel Holter monitor.
(7) It is concluded the decrease in cellular volume associated with substitution of serosal gluconate for Cl results in a loss of highly specific Ba2+-sensitive K+ conductance channels from the basolateral plasma membrane.
(8) Stimulation of atrial H1-receptors is suggested to directly cause an increase in Ca-channel conductance independent of intracellular cAMP content.
(9) Similarly, 50 microM D-600, a Ca+2 channel antagonist, significantly (P less than 0.01) reduced basal and 5-HETE-induced PRL release.
(10) The purpose of the present study was to analyze the effects of cromakalim (BRL 34915), a potent drug from a new class of drugs characterized as "K+ channel openers", on the electrical activity of human skeletal muscle.
(11) This promotion of repetitive activity by the introduction of additional potassium channels occurred up to an "optimal" value beyond which a further increase in paranodal potassium permeability narrowed the range of currents with a repetitive response.
(12) Channel activation persists through the process of platelet isolation and washing and is manifested in higher measured values of [Ca2+]cyt and [Ca2+]dt in the "resting state."
(13) At 100 microM-ACh the apparent open time became shorter probably due to channel blockade by ACh molecules.
(14) The effects of low doses of dihydropyridine (DHP) calcium channel antagonists nimodipine, nifedipine, (-)-R-202-791, and amlodipine, the DHP calcium channel agonist BAY K 8644 were investigated on clonic convulsions to pentylenetetrazole (PTZ) in mice.
(15) The following model is suggested: exogenous ATP interacts with a membrane receptor in the presence of Ca2+, a cascade of events occurs which mobilizes intracellular calcium, thereby increasing the cytosolic free Ca2+ concentration which consequently opens the calcium-activated K+ channels, which then leads to a change in membrane potential.
(16) SDS-PAGE analysis of the immunoprecipitates under reducing conditions revealed that the cardiac channel is mainly composed of two large polypeptides of 190 and 150 kDa, and five smaller polypeptides of 60, 55, 35, 30, and 25 kDa.
(17) In the presence of high external Cl, a component of outward current that was inhibited by the anion channel blocker diphenylamine-2-carboxylate (DPC) appeared in 70% of the cells.
(18) In vitro studies in cardiac Purkinje fibers suggested that reversal of amitriptyline-induced cardiac membrane effects by sodium bicarbonate may be attributed not only to alkalinization but also to increased in extracellular sodium concentration, diminishing the local anesthetic action of amitriptyline and resulting in less sodium channel block.
(19) The Ca2+ channel current recorded under identical conditions in rat dorsal root ganglion neurones was less sensitive to blockade by PCP (IC50, 90 microM).
(20) In voltage-clamp experiments the ion current flowing through the channels was homogeneous indicating a defined conformation and a uniform size.
Gully
Definition:
(n.) A large knife.
(n.) A channel or hollow worn in the earth by a current of water; a short deep portion of a torrent's bed when dry.
(n.) A grooved iron rail or tram plate.
(v. t.) To wear into a gully or into gullies.
(v. i.) To flow noisily.
Example Sentences:
(1) Some fields had lightly furrowed brows, others deep gullies and humpbacked hills.
(2) From the third ball, though, he makes good his escape with a thick edge through the gully region for a single.
(3) Transporting heavy building materials across dirt streets riven with gullies and piled high with detritus is not easy, and theft of building materials is commonplace in Kibera.
(4) Nearly a decade ago, Nasa’s Mars Global Surveyor took pictures of what appeared to be water bursting through a gully wall and flowing around boulders and other rocky debris.
(5) Last week, the search turned to a gully near a rubbish dump in the neighbouring city of Cocula, but still no remains have been identified.
(6) Andy Wilson (@andywiz) England on course to bowl 14 or even 15 overs in the first hour June 20, 2014 11.38am BST 9th over: Sri Lanka 24-0 (Karunaratne 10, Silva 10) Karunaratne picks up four more with the squirtiest of squirty drives that zips away through gully.
(7) Accessible only on foot, the Needles section of the Canyonlands national park has pink and creamy turrets, chimneys, gullies, mysterious canyons and weird formations.
(8) They show people in white jump suits working at the bottom of the gully reportedly about 10m deep and reachable only with the help of ropes.
(9) Pools of ticks, Ixodes (Ceratixodes) uriae collected between 1975 and 1979 at Macquarie Island, yielded 33 strains of at least 4 different viruses: Nugget virus (Kemerovo group), 1 strain; Taggert virus (Sakhalin group) 9 strains; a previously undescribed flavivirus, related to Central European Tickborne encephalitis virus, for which the name "Gadgets Gully" is proposed, 9 strains; a virus serologically related to the Uukuniemi serogroup, family Bunyaviridae, for which the name "Precarious Point" is proposed, 10 strains.
(10) Facebook Twitter Pinterest Sheep graze next to a dried-out gully usually flowing with spring water, in the Palestinian village of al-Auja, near Jericho.
(11) The St. Agnes Community Health Centre was established in October 1974, in the rapidly growing area of Tea Tree Gully, South Australia.
(12) Updated at 11.33am BST 11.22am BST 32nd over: England 68-5 (Root 7, Ali 10) Moeen sees a wide one, and, keen to attack, cuts hard and high past gully for four.
(13) In the western city of Lanzhou, officially deemed by the World Health Organisation to have the worst air in China , officials have proposed digging great gullies into the surrounding mountains in the hope of trapping polluted air in a gigantic landscape gutter, like an atmospheric ha-ha.
(14) Broad's not bowled well today, but he tempts Sangakkara with slight width - and Sangakkara flashes, toe-ending to gully, where Bell dives low and left to snaffle an excellent catch.
(15) VVS Laxman played an injudicious shot off Lonwabo Tsotsobe, edging to gully, before Suresh Raina offered catching practice to Harris at first slip.
(16) The search for 43 student teachers who went missing in Mexico a month ago is now focusing on a gully on the edge of a municipal rubbish dump.
(17) The pier is plenty deep for diving, with access to a narrow gully beneath the drawbridge and a pristine, horse-shoe beach on the opposite side of the fort.
(18) Antibodies to a potentially harmful flavivirus, Gadget's Gully virus, were equally present (4%) in both avian and human sera.
(19) Around noon every day, automated pumps just above the pond are switched on and for the next few hours 400,000 gallons (1.8m litres) of water are sent cascading down a brick-lined gully into the lake.
(20) It was also a place of sandy gullies formed by sporadic streams in the rainy season, where nomads brought their camels.