(n.) The hollow bed where a stream of water runs or may run.
(n.) The deeper part of a river, harbor, strait, etc., where the main current flows, or which affords the best and safest passage for vessels.
(n.) A strait, or narrow sea, between two portions of lands; as, the British Channel.
(n.) That through which anything passes; means of passing, conveying, or transmitting; as, the news was conveyed to us by different channels.
(n.) A gutter; a groove, as in a fluted column.
(n.) Flat ledges of heavy plank bolted edgewise to the outside of a vessel, to increase the spread of the shrouds and carry them clear of the bulwarks.
(v. t.) To form a channel in; to cut or wear a channel or channels in; to groove.
(v. t.) To course through or over, as in a channel.
Example Sentences:
(1) These channels may, at least in some cases, be responsible for the generation of pacemaker depolarizations, thereby regulating firing behaviour.
(2) The influence of the various concepts for the induction of lateral structure formation in lipid membranes on integral functional units like ionophores is demonstrated by analysing the single channel current fluctuations of gramicidin in bimolecular lipid membranes.
(3) RNAs encoding a wild-type (RBK1) and a mutant (RBK1(Y379V,V381T); RBK1*) subunit of voltage-dependent potassium channels were injected into Xenopus oocytes.
(4) The dramas are part of the BBC2 controller Janice Hadlow's plans for her "unashamedly intelligent" channel over the coming months.
(5) This was unlike the action of the calcium channel blocker, cadmium, which reduced the calcium action potential and the a.h.p.
(6) Circuitry has been developed to feed the output of an ear densitogram pickup into one channel of a two-channel Holter monitor.
(7) It is concluded the decrease in cellular volume associated with substitution of serosal gluconate for Cl results in a loss of highly specific Ba2+-sensitive K+ conductance channels from the basolateral plasma membrane.
(8) Stimulation of atrial H1-receptors is suggested to directly cause an increase in Ca-channel conductance independent of intracellular cAMP content.
(9) Similarly, 50 microM D-600, a Ca+2 channel antagonist, significantly (P less than 0.01) reduced basal and 5-HETE-induced PRL release.
(10) The purpose of the present study was to analyze the effects of cromakalim (BRL 34915), a potent drug from a new class of drugs characterized as "K+ channel openers", on the electrical activity of human skeletal muscle.
(11) This promotion of repetitive activity by the introduction of additional potassium channels occurred up to an "optimal" value beyond which a further increase in paranodal potassium permeability narrowed the range of currents with a repetitive response.
(12) Channel activation persists through the process of platelet isolation and washing and is manifested in higher measured values of [Ca2+]cyt and [Ca2+]dt in the "resting state."
(13) At 100 microM-ACh the apparent open time became shorter probably due to channel blockade by ACh molecules.
(14) The effects of low doses of dihydropyridine (DHP) calcium channel antagonists nimodipine, nifedipine, (-)-R-202-791, and amlodipine, the DHP calcium channel agonist BAY K 8644 were investigated on clonic convulsions to pentylenetetrazole (PTZ) in mice.
(15) The following model is suggested: exogenous ATP interacts with a membrane receptor in the presence of Ca2+, a cascade of events occurs which mobilizes intracellular calcium, thereby increasing the cytosolic free Ca2+ concentration which consequently opens the calcium-activated K+ channels, which then leads to a change in membrane potential.
(16) SDS-PAGE analysis of the immunoprecipitates under reducing conditions revealed that the cardiac channel is mainly composed of two large polypeptides of 190 and 150 kDa, and five smaller polypeptides of 60, 55, 35, 30, and 25 kDa.
(17) In the presence of high external Cl, a component of outward current that was inhibited by the anion channel blocker diphenylamine-2-carboxylate (DPC) appeared in 70% of the cells.
(18) In vitro studies in cardiac Purkinje fibers suggested that reversal of amitriptyline-induced cardiac membrane effects by sodium bicarbonate may be attributed not only to alkalinization but also to increased in extracellular sodium concentration, diminishing the local anesthetic action of amitriptyline and resulting in less sodium channel block.
(19) The Ca2+ channel current recorded under identical conditions in rat dorsal root ganglion neurones was less sensitive to blockade by PCP (IC50, 90 microM).
(20) In voltage-clamp experiments the ion current flowing through the channels was homogeneous indicating a defined conformation and a uniform size.
Sound
Definition:
(n.) The air bladder of a fish; as, cod sounds are an esteemed article of food.
(n.) A cuttlefish.
(superl.) Whole; unbroken; unharmed; free from flaw, defect, or decay; perfect of the kind; as, sound timber; sound fruit; a sound tooth; a sound ship.
(superl.) Healthy; not diseased; not being in a morbid state; -- said of body or mind; as, a sound body; a sound constitution; a sound understanding.
(superl.) Firm; strong; safe.
(superl.) Free from error; correct; right; honest; true; faithful; orthodox; -- said of persons; as, a sound lawyer; a sound thinker.
(superl.) Founded in truth or right; supported by justice; not to be overthrown on refuted; not fallacious; as, sound argument or reasoning; a sound objection; sound doctrine; sound principles.
(superl.) heavy; laid on with force; as, a sound beating.
(superl.) Founded in law; legal; valid; not defective; as, a sound title to land.
(adv.) Soundly.
(n.) A narrow passage of water, or a strait between the mainland and an island; also, a strait connecting two seas, or connecting a sea or lake with the ocean; as, the Sound between the Baltic and the german Ocean; Long Island Sound.
(v. t.) To measure the depth of; to fathom; especially, to ascertain the depth of by means of a line and plummet.
(v. t.) Fig.: To ascertain, or try to ascertain, the thoughts, motives, and purposes of (a person); to examine; to try; to test; to probe.
(v. t.) To explore, as the bladder or urethra, with a sound; to examine with a sound; also, to examine by auscultation or percussion; as, to sound a patient.
(v. i.) To ascertain the depth of water with a sounding line or other device.
(n.) Any elongated instrument or probe, usually metallic, by which cavities of the body are sounded or explored, especially the bladder for stone, or the urethra for a stricture.
(n.) The peceived object occasioned by the impulse or vibration of a material substance affecting the ear; a sensation or perception of the mind received through the ear, and produced by the impulse or vibration of the air or other medium with which the ear is in contact; the effect of an impression made on the organs of hearing by an impulse or vibration of the air caused by a collision of bodies, or by other means; noise; report; as, the sound of a drum; the sound of the human voice; a horrid sound; a charming sound; a sharp, high, or shrill sound.
(n.) The occasion of sound; the impulse or vibration which would occasion sound to a percipient if present with unimpaired; hence, the theory of vibrations in elastic media such cause sound; as, a treatise on sound.
(n.) Noise without signification; empty noise; noise and nothing else.
(v. i.) To make a noise; to utter a voice; to make an impulse of the air that shall strike the organs of hearing with a perceptible effect.
(v. i.) To be conveyed in sound; to be spread or published; to convey intelligence by sound.
(v. i.) To make or convey a certain impression, or to have a certain import, when heard; hence, to seem; to appear; as, this reproof sounds harsh; the story sounds like an invention.
(v. t.) To causse to make a noise; to play on; as, to sound a trumpet or a horn.
(v. t.) To cause to exit as a sound; as, to sound a note with the voice, or on an instrument.
(v. t.) To order, direct, indicate, or proclain by a sound, or sounds; to give a signal for by a certain sound; as, to sound a retreat; to sound a parley.
(v. t.) To celebrate or honor by sounds; to cause to be reported; to publish or proclaim; as, to sound the praises of fame of a great man or a great exploit.
(v. t.) To examine the condition of (anything) by causing the same to emit sounds and noting their character; as, to sound a piece of timber; to sound a vase; to sound the lungs of a patient.
(v. t.) To signify; to import; to denote.
Example Sentences:
(1) The sound of the ambulance frightened us, especially us children, and panic gripped the entire community: people believe that whoever is taken into the ambulance to the hospital will die – you so often don’t see them again.
(2) Here, we review the nature of the heart sound signal and the various signal-processing techniques that have been applied to PCG analysis.
(3) Our experience indicates that lateral rhinotomy is a safe, repeatable and cosmetically sound procedure that provides and excellent surgical approach to the nasal cavity and sinuses.
(4) Compared with conservative management, better long-term success (determined by return of athletic soundness and less evidence of degenerative joint disease) was achieved with surgical curettage of elbow subchondral cystic lesions.
(5) Respiratory alteration in the intensity of heart sounds is one of the commonest auscultatory pitfalls.
(6) I usually use them as a rag with which to clean the toilet but I didn’t have anything else to wear today because I’m so fat.” While this exchange will sound baffling to outsiders, to Brits it actually sounds like this: “You like my dress?
(7) It is felt that otologic surgery should be done before the pinna reconstruction as it is very important to try and introduce sound into these children at an early age.
(8) To evaluate the relationship between the motion pattern and degree of organic change of the anterior mitral leaflet (AML) and the features of the mitral component of the first heart sound (M1) or the opening snap (OS), 37 patients with mitral stenosis (MS) were studied by auscultation, phonocardiography and echocardiography.
(9) The talent base in the UK – not just producers and actors but camera and sound – is unparalleled, so I think creativity will continue unabated.” Lee does recognise “massive” cultural differences between the US and UK.
(10) Among the epileptic patients investigated by the stereotactic E. E. G. (Talairach) whose electrodes were introduced at or around the auditory cortex (Area 41, 42), the topography of the auditory responses by the electrical bipolar stimulation and that of the auditory evoked potential by the bilateral click sound stimulation were studied in relation to the ac--pc line (Talairach).
(11) Seconds later the camera turns away as what sounds like at least 15 gunshots are fired amid bystanders’ screams.
(12) Not making a sound for 24 hours pretty nearly killed me.
(13) The decision of the editors to solicit a review for the Medical Progress series of this journal devoted to current concepts of the renal handling of salt and water is sound in that this important topic in kidney physiology has recently been the object of a number of new, exciting and, in some instances, quite unexpected insights into the mechanisms governing sodium excretion.
(14) Reduced mineral absorption is fairly well documented and has sound theoretical support from basic chemistry.
(15) Endogenous sound-induced (binaural) inhibition which is suggested to be GABA-mediated is also significantly reduced in IC neurons of the GEPR.
(16) Five horses raced successfully and lowered the lifetime race records, 1 horse was sound and trained successfully, but died of colic, and 1 horse was not lame in early training.
(17) This paper reports two experiments concerned with verbal representation in the test stage of recognition memory for naturalistic sounds.
(18) Although sound pressure levels are high, they are probably reduced before reaching the cochlea of the fetus because of the surrounding amniotic fluid and the fluid in the middle ear.
(19) The purpose of the present study was to investigate the effects of listening experience on the perception of intraphonemic differences in the absence of specific training with the synthetic speech sounds being tested.
(20) Digital respirosonography provides an easy way to assess lung sound amplitudes, frequencies and timing over several breaths.